RESUMO
Pilonidal sinus is a common disease that causes the loss of many working hours, but treatment is variable and problematic. The effect of gentamicin-absorbed collagen on healing, infection and recurrence, and length of hospital stay were examined after pilonidal sinus surgery. Patients undergoing surgical treatment for pilonidal sinus were randomly assigned into two groups each of 40 patients. Both groups were treated with excision and primary closure under local anaesthesia. Group 1 (control) received oral antibiotics for 7 days post-operatively. In group 2, prior to wound closure, gentamicin-absorbed collagen sponges were placed on the sacral fascia and these patients did not receive oral post-operative antibiotic therapy. Patients in group 2 had a significantly shorter mean wound healing time, significantly lower infection and recurrence rates, and a significantly shorter hospital stay than those in group 1. It is concluded that implantation of a gentamicin-containing collagen sponge on the wound area in pilonidal sinus decreased the rates of infection and recurrence, and shortened the hospital stay.
Assuntos
Antibacterianos/administração & dosagem , Colágeno , Gentamicinas/administração & dosagem , Seio Pilonidal/tratamento farmacológico , Tampões de Gaze Cirúrgicos , Administração Oral , Administração Tópica , Implantes de Medicamento , Humanos , Tempo de Internação , Seio Pilonidal/patologia , Seio Pilonidal/cirurgia , Estudos Prospectivos , Infecção da Ferida Cirúrgica/prevenção & controle , Resultado do Tratamento , CicatrizaçãoRESUMO
This study investigated the effects of Gentacoll implants on healing in patients (n = 44) undergoing modified radical mastectomy and axillary dissection. Group I, the Gentacoll group (n = 22), underwent surgery followed by insertion of 10 × 10 × 0.5 cm Gentacoll implants (280 mg collagen sponge plus 200 mg gentamicin sulphate) into the axillary area and under the flap area of the breast before wound closure. Group II, the control group (n = 22), underwent surgery without the application of Gentacoll. Neither group received oral or parenteral post-operative antibiotic therapy. Outcome measures included wound infection, seroma formation, total drainage volumes, drain removal time and duration of hospital stay. Post-operative infection rate, seroma formation, drainage volumes and duration of hospital stay were significantly reduced in the Gentacoll group compared with the control group. In conclusion, the application of Gentacoll significantly improved post-operative outcomes in patients undergoing modified radical mastectomy.
Assuntos
Antibacterianos/farmacologia , Antibacterianos/uso terapêutico , Gentamicinas/farmacologia , Gentamicinas/uso terapêutico , Mastectomia Radical Modificada , Infecção da Ferida Cirúrgica/tratamento farmacológico , Cicatrização/efeitos dos fármacos , Implantes de Mama , Drenagem , Feminino , Gentamicinas/administração & dosagem , Humanos , Linfonodos/efeitos dos fármacos , Linfonodos/patologia , Pessoa de Meia-Idade , Cuidados Pós-Operatórios , Estudos Prospectivos , Resultado do TratamentoRESUMO
A femoral hernia is the protrusion of the abdominal contents through the femoral canal. It accounts for less than 1% of all groin hernias in children and is often confused with inguinal hernia or other inguinal pathologies. Preoperative misdiagnosis has been reported to be between 40 and 75%. We believe that misdiagnosis and mistreatment usually occur due to insufficient physical examination, knowledge and experience about childhood femoral hernias. Here, we report and discuss the clinical appearance and treatment approach of three patients operated with the diagnosis of femoral hernias.