Detalhe da pesquisa
1.
Phosphatases maintain low catalytic activity of SGK1: DNA damage resets the balance in favor of phosphorylation.
J Biol Chem
; 299(8): 104941, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37343701
2.
Lipid droplets and autophagosomes together with chaperones fine-tune expression of SGK1.
J Cell Mol Med
; 26(10): 2852-2865, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35393773
3.
A method for activation of endogenous acid-sensing ion channel 1a (ASIC1a) in the nervous system with high spatial and temporal precision.
J Biol Chem
; 289(22): 15441-8, 2014 May 30.
Artigo
Inglês
| MEDLINE | ID: mdl-24727474
4.
The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression.
Int J Mol Sci
; 16(4): 7462-77, 2015 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-25849655
5.
Impact of recovery from desensitization on acid-sensing ion channel-1a (ASIC1a) current and response to high frequency stimulation.
J Biol Chem
; 287(48): 40680-9, 2012 Nov 23.
Artigo
Inglês
| MEDLINE | ID: mdl-23048040
6.
Heterogeneous nuclear ribonucleoprotein A2/B1 is a tissue-specific aldosterone target gene with prominent induction in the rat distal colon.
Am J Physiol Gastrointest Liver Physiol
; 304(2): G122-31, 2013 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23139218
7.
A flexible GAS belt responds to pore mutations changing the ion selectivity of proton-gated channels.
J Gen Physiol
; 154(1)2022 01 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34766968
8.
Asn415 in the beta11-beta12 linker decreases proton-dependent desensitization of ASIC1.
J Biol Chem
; 285(41): 31285-91, 2010 Oct 08.
Artigo
Inglês
| MEDLINE | ID: mdl-20675379
9.
Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation.
J Biol Chem
; 285(29): 22706-12, 2010 Jul 16.
Artigo
Inglês
| MEDLINE | ID: mdl-20479002
10.
A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons.
Proc Natl Acad Sci U S A
; 105(11): 4459-64, 2008 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-18334630
11.
An arginine residue in the outer segment of hASIC1a TM1 affects both proton affinity and channel desensitization.
J Gen Physiol
; 153(5)2021 05 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33851970
12.
Structure and analysis of nanobody binding to the human ASIC1a ion channel.
Elife
; 102021 07 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34319232
13.
Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel.
Am J Physiol Cell Physiol
; 299(1): C66-73, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20427715
14.
Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1.
Mol Biol Cell
; 18(6): 2072-80, 2007 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-17377066
15.
Simple chordates exhibit a proton-independent function of acid-sensing ion channels.
FASEB J
; 22(6): 1914-23, 2008 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-18211956
16.
A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels.
Elife
; 82019 05 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31045491
17.
Structural biology: unexpected opening.
Nature
; 449(7160): 293-4, 2007 Sep 20.
Artigo
Inglês
| MEDLINE | ID: mdl-17882209
18.
Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism.
J Gen Physiol
; 127(2): 109-17, 2006 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-16418400
19.
Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes.
J Gen Physiol
; 120(4): 553-66, 2002 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-12356856
20.
Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells.
J Gen Physiol
; 119(5): 427-42, 2002 May.
Artigo
Inglês
| MEDLINE | ID: mdl-11981022