Detalhe da pesquisa
1.
Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents.
Cell
; 186(5): 1013-1025.e24, 2023 03 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36827973
2.
Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria.
Malar J
; 22(1): 2, 2023 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36597076
3.
A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria.
Malar J
; 20(1): 222, 2021 May 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34011358
4.
Safety and efficacy of the choline analogue SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter trials in African patients.
Malar J
; 16(1): 188, 2017 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28472957
5.
A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study.
Malar J
; 15: 469, 2016 Sep 13.
Artigo
Inglês
| MEDLINE | ID: mdl-27624471
6.
Safety, pharmacokinetics, and target engagement of a brain penetrant RIPK1 inhibitor, SAR443820 (DNL788), in healthy adult participants.
Clin Transl Sci
; 17(1): e13690, 2024 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38010108
7.
Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Malaria.
Am J Trop Med Hyg
; 97(2): 514-525, 2017 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-28722611
8.
Ferroquine and artesunate in African adults and children with Plasmodium falciparum malaria: a phase 2, multicentre, randomised, double-blind, dose-ranging, non-inferiority study.
Lancet Infect Dis
; 15(12): 1409-19, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26342427