Detalhe da pesquisa
1.
Single-Nucleus RNA-Seq Reveals Dysregulation of Striatal Cell Identity Due to Huntington's Disease Mutations.
J Neurosci
; 41(25): 5534-5552, 2021 06 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34011527
2.
Transcriptional regulatory networks underlying gene expression changes in Huntington's disease.
Mol Syst Biol
; 14(3): e7435, 2018 03 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29581148
3.
Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation.
Life Sci Alliance
; 6(11)2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37684045
4.
Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation.
bioRxiv
; 2023 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-37425835
5.
Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration.
J Neurosci
; 31(22): 8306-19, 2011 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21632951
6.
Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease.
Cell Syst
; 13(4): 304-320.e5, 2022 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35148841
7.
Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice.
Neuron
; 110(7): 1173-1192.e7, 2022 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35114102
8.
Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1.
Commun Biol
; 4(1): 1374, 2021 12 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34880419
9.
Early Detection of Apathetic Phenotypes in Huntington's Disease Knock-in Mice Using Open Source Tools.
Sci Rep
; 8(1): 2304, 2018 02 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29396492
10.
Common and divergent structural features of a series of corticotropin releasing factor-related peptides.
J Am Chem Soc
; 129(51): 16102-14, 2007 Dec 26.
Artigo
Inglês
| MEDLINE | ID: mdl-18052377
11.
Stressin1-A, a potent corticotropin releasing factor receptor 1 (CRF1)-selective peptide agonist.
J Med Chem
; 50(7): 1668-74, 2007 Apr 05.
Artigo
Inglês
| MEDLINE | ID: mdl-17335188
12.
Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease.
PLoS One
; 12(4): e0175968, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28453524
13.
Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.
Sci Rep
; 7: 41570, 2017 02 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28176805
14.
Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Nat Neurosci
; 19(4): 623-33, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26900923
15.
N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice.
Neuron
; 85(4): 726-41, 2015 Feb 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25661181
16.
Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
Nat Med
; 20(5): 536-41, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24784230
17.
Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis.
FEBS J
; 280(18): 4382-94, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23829302
18.
Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.
Sci Rep
; 7: 44960, 2017 03 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28350386
19.
Fate of cajal-retzius neurons in the postnatal mouse neocortex.
Front Neuroanat
; 4: 10, 2010.
Artigo
Inglês
| MEDLINE | ID: mdl-20339484
20.
Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand.
Proc Natl Acad Sci U S A
; 104(12): 4858-63, 2007 Mar 20.
Artigo
Inglês
| MEDLINE | ID: mdl-17360332