Detalhe da pesquisa
1.
Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment.
Genomics
; 102(3): 157-62, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23434628
2.
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.
Cell Chem Biol
; 30(10): 1191-1210.e20, 2023 10 19.
Artigo
Inglês
| MEDLINE | ID: mdl-37557181
3.
HIV capsid is a tractable target for small molecule therapeutic intervention.
PLoS Pathog
; 6(12): e1001220, 2010 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-21170360
4.
Comparative biomarker analysis of PALOMA-2/3 trials for palbociclib.
NPJ Precis Oncol
; 6(1): 56, 2022 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35974168
5.
New small-molecule inhibitor class targeting human immunodeficiency virus type 1 virion maturation.
Antimicrob Agents Chemother
; 53(12): 5080-7, 2009 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-19805571
6.
Combining CDK4/6 inhibition with taxanes enhances anti-tumor efficacy by sustained impairment of pRB-E2F pathways in squamous cell lung cancer.
Oncogene
; 38(21): 4125-4141, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30700828
7.
A novel HIV-1 antiviral high throughput screening approach for the discovery of HIV-1 inhibitors.
Antiviral Res
; 65(2): 107-16, 2005 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-15708637
8.
Molecular predictors of sensitivity to the insulin-like growth factor 1 receptor inhibitor Figitumumab (CP-751,871).
Mol Cancer Ther
; 12(12): 2929-39, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24107449
9.
Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line.
Front Med
; 7(4): 462-76, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23820871
10.
Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation.
PLoS One
; 8(6): e67258, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23826249
11.
An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735.
Mol Cancer Ther
; 11(3): 710-9, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22222631
12.
Identification and characterization of UK-201844, a novel inhibitor that interferes with human immunodeficiency virus type 1 gp160 processing.
Antimicrob Agents Chemother
; 51(10): 3554-61, 2007 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17646410
13.
High-throughput human immunodeficiency virus type 1 (HIV-1) full replication assay that includes HIV-1 Vif as an antiviral target.
Antimicrob Agents Chemother
; 49(9): 3833-41, 2005 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-16127060