Detalhe da pesquisa
1.
Targeting Epigenetic Regulators with HDAC and BET Inhibitors to Modulate Muscle Wasting.
Int J Mol Sci
; 24(22)2023 Nov 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38003594
2.
DCLK1, a Putative Stem Cell Marker in Human Cholangiocarcinoma.
Hepatology
; 73(1): 144-159, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32978808
3.
Exercise and Exercise Mimetics for the Treatment of Musculoskeletal Disorders.
Curr Osteoporos Rep
; 20(5): 249-259, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35881303
4.
SMYD3 promotes the epithelial-mesenchymal transition in breast cancer.
Nucleic Acids Res
; 47(3): 1278-1293, 2019 02 20.
Artigo
Inglês
| MEDLINE | ID: mdl-30544196
5.
The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy.
Genes Dev
; 27(11): 1299-312, 2013 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23752591
6.
Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins by JQ1 Unravels a Novel Epigenetic Modulation to Control Lipid Homeostasis.
Int J Mol Sci
; 21(4)2020 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32075110
7.
A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth.
J Cell Physiol
; 230(10): 2447-2460, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25728514
8.
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity.
J Adv Res
; 2024 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38365172
9.
Tackling skeletal muscle cells epigenome in the next-generation sequencing era.
Comp Funct Genomics
; 2012: 979168, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22701348
10.
Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3.
Eur J Med Chem
; 243: 114683, 2022 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36116234
11.
The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.
Dev Cell
; 11(4): 547-60, 2006 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17011493
12.
In vitro profiling of epigenetic modifications underlying heavy metal toxicity of tungsten-alloy and its components.
Toxicol Appl Pharmacol
; 253(3): 178-87, 2011 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21513724
13.
The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development.
Cells
; 10(5)2021 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34069776
14.
Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool.
Diagnostics (Basel)
; 11(11)2021 Nov 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34829505
15.
SMYD3: An Oncogenic Driver Targeting Epigenetic Regulation and Signaling Pathways.
Cancers (Basel)
; 12(1)2020 Jan 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31935919
16.
BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy.
Nat Commun
; 11(1): 6108, 2020 11 30.
Artigo
Inglês
| MEDLINE | ID: mdl-33257646
17.
Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality.
iScience
; 23(10): 101604, 2020 Oct 23.
Artigo
Inglês
| MEDLINE | ID: mdl-33205017
18.
Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin.
Dev Cell
; 6(5): 673-84, 2004 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15130492
19.
Mechanisms underlying the transcriptional regulation of skeletal myogenesis.
Curr Opin Genet Dev
; 15(5): 528-35, 2005 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-16055324
20.
Interplay between Metabolites and the Epigenome in Regulating Embryonic and Adult Stem Cell Potency and Maintenance.
Stem Cell Reports
; 13(4): 573-589, 2019 10 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31597110