Detalhe da pesquisa
1.
The crosstalk between gut barrier impairment, mitochondrial dysfunction, and microbiota alterations in people living with HIV.
J Med Virol
; 95(1): e28402, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36515414
2.
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy.
FASEB J
; 35(1): e21271, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33368684
3.
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics.
J Chem Inf Model
; 62(1): 196-209, 2022 01 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34914393
4.
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity.
J Immunol
; 204(9): 2535-2551, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32213564
5.
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR).
Bioorg Chem
; 111: 104897, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33901797
6.
Bile Acid Signaling in Inflammatory Bowel Diseases.
Dig Dis Sci
; 66(3): 674-693, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33289902
7.
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis.
FASEB J
; 33(2): 2809-2822, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30303744
8.
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.
J Immunol
; 199(2): 718-733, 2017 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28607110
9.
Signaling from Intestine to the Host: How Bile Acids Regulate Intestinal and Liver Immunity.
Handb Exp Pharmacol
; 256: 95-108, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31119464
10.
Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties.
Molecules
; 24(6)2019 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-30884797
11.
Disruption of TFGß-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand.
Pharmacol Res
; 131: 17-31, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29530598
12.
Phallusiasterol C, A New Disulfated Steroid from the Mediterranean Tunicate Phallusia fumigata.
Mar Drugs
; 14(6)2016 Jun 18.
Artigo
Inglês
| MEDLINE | ID: mdl-27322293
13.
Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.
Am J Physiol Heart Circ Physiol
; 309(1): H114-26, 2015 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25934094
14.
FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents.
Pharmacol Res
; 77: 1-10, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24004655
15.
Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis.
Mar Drugs
; 12(1): 36-53, 2013 Dec 24.
Artigo
Inglês
| MEDLINE | ID: mdl-24368568
16.
HIV-1 infection is associated with changes in nuclear receptor transcriptome, pro-inflammatory and lipid profile of monocytes.
BMC Infect Dis
; 12: 274, 2012 Oct 29.
Artigo
Inglês
| MEDLINE | ID: mdl-23106848
17.
Bile acids and their receptors in metabolic disorders.
Prog Lipid Res
; 82: 101094, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33636214
18.
Bile Acids Activated Receptors in Inflammatory Bowel Disease.
Cells
; 10(6)2021 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34064187
19.
Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential.
Front Oncol
; 11: 663771, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34012923
20.
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction.
Biochem Pharmacol
; 188: 114564, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33872570