RESUMO
The authors report a case of angiosarcoma of the descending thoracic aorta presenting with a metastasis of the small intestine. This is a very rare tumour in this localisation, two cases having been described among the 28 cases of aortic tumour reported in the literature.
Assuntos
Aorta Torácica , Hemangiossarcoma , Neoplasias Intestinais/secundário , Diagnóstico por Imagem , Humanos , Neoplasias Intestinais/patologia , Masculino , Pessoa de Meia-IdadeRESUMO
We report a case of aortic endothelioma revealed by intestinal metastasis in a man who was admitted for severe anemia, left heart failure, and fatal ileo-mesenteric infarction. This is the 13th published case of aortic endothelioma, and the first case revealed by intestinal metastasis. It illustrates the value of the magnetic resonance imaging for the detection of an aortic tumor when intestinal angiosarcoma has been diagnosed. The surgical treatment could improve an otherwise very poor prognosis.
Assuntos
Aorta Torácica , Hemangiossarcoma/diagnóstico , Neoplasias do Íleo/secundário , Hemangiossarcoma/patologia , Hemangiossarcoma/secundário , Hemangiossarcoma/cirurgia , Humanos , Neoplasias do Íleo/patologia , Neoplasias do Íleo/cirurgia , Masculino , Pessoa de Meia-Idade , Doenças Vasculares/diagnóstico , Doenças Vasculares/patologia , Doenças Vasculares/cirurgiaRESUMO
The authors report 2 cases of primary melanoma of the esophagus, and describes the clinical, endoscopical, radiological and histological features from these exceptional tumors. Prognosis is very poor, despite various therapeutical possibilities.
Assuntos
Neoplasias Esofágicas/diagnóstico por imagem , Melanoma/diagnóstico por imagem , Idoso , Neoplasias Ósseas/secundário , Neoplasias Ósseas/terapia , Endoscopia do Sistema Digestório , Neoplasias Esofágicas/patologia , Neoplasias Esofágicas/cirurgia , Neoplasias Esofágicas/ultraestrutura , Esofagectomia , Evolução Fatal , Humanos , Neoplasias Pulmonares/secundário , Neoplasias Pulmonares/terapia , Masculino , Melanoma/patologia , Melanoma/cirurgia , Melanoma/ultraestrutura , Microscopia , Pessoa de Meia-Idade , RadiografiaRESUMO
Neoplastic meningitis as the presentation of occult primitive neuroectodermal tumor (PNET) is occasionally described in children. We report the case of an 64 year old-man who presented a meningo-radiculopathy with progressive injury of the cauda equina and then the ocular motor nerves, revealing an occult medulloblastoma-PNET.
Assuntos
Neoplasias Cerebelares/diagnóstico , Meduloblastoma/diagnóstico , Meningite/etiologia , Tumores Neuroectodérmicos Primitivos/diagnóstico , Polirradiculopatia/etiologia , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasias Cerebelares/tratamento farmacológico , Neoplasias Cerebelares/patologia , Cisplatino/administração & dosagem , Etoposídeo/administração & dosagem , Humanos , Imageamento por Ressonância Magnética , Masculino , Meduloblastoma/tratamento farmacológico , Meduloblastoma/patologia , Meningite/patologia , Metotrexato/administração & dosagem , Pessoa de Meia-Idade , Tumores Neuroectodérmicos Primitivos/tratamento farmacológico , Tumores Neuroectodérmicos Primitivos/patologia , Nervo Oculomotor/patologia , Polirradiculopatia/patologiaRESUMO
We report a case of a 68 years old male patient treated for chronic lymphocytic leukaemia, presenting a right inguino-crural tender lymphadenopathy with periadenitis. The histologic changes associated with adenitis were large foci of necrosis with regular crown of epithelioid cells, without giant cell. The presence of Herpes simplex virus 2 was confirmed by immunohistochemistry and culture. Occurrence, physiopathology, clinical and histological aspects of Herpes simplex lymphadenitis in patients with haematologic disorders, are discussed.
Assuntos
Herpes Simples/complicações , Leucemia Linfocítica Crônica de Células B/complicações , Linfadenite/etiologia , Idoso , Azul Alciano , Técnicas de Cultura , Imunofluorescência , Humanos , Imuno-Histoquímica , Linfadenite/patologia , Linfócitos/imunologia , Masculino , NecroseRESUMO
We report a case of perforated infectious crystalline keratopathy in a 88-year-old woman. Corneal surgery like keratoplasty and topical corticosteroids are the main causative factors present in the rare reported cases. Clinically, the anterior layers of cornea exhibit slowly progressive stellate infiltrates. "Viridans streptococci" are the most common micro-organisms involved but their culture for identification is difficult. As compared to cultures, histologic examination is more sensitive for diagnosis, by showing clusters of bacteria in the corneal stroma with no inflammatory response.
Assuntos
Doenças da Córnea/microbiologia , Doenças da Córnea/patologia , Administração Tópica , Idoso , Idoso de 80 Anos ou mais , Anti-Inflamatórios/efeitos adversos , Doenças da Córnea/etiologia , Feminino , Glucocorticoides , Bactérias Gram-Positivas/isolamento & purificação , HumanosRESUMO
Often mentioned and not much documented, the lipoblastic meningioma is an unusual extra-axial benign tumor. It has spontaneously hypodensity in CT and appears with a high signal in MRI in T1-weighted sequence. Its vascularisation is rich and shows a strong contrast intake. Its resection is known as easy and its prognosis is excellent. The authors report here the observation of a 65 year old women having a lipoblastic meningioma. Literature is gone through and differential diagnoses are considered.
Assuntos
Neoplasias Meníngeas/diagnóstico por imagem , Meningioma/diagnóstico por imagem , Idoso , Diagnóstico Diferencial , Feminino , Humanos , Imageamento por Ressonância Magnética , Neoplasias Meníngeas/diagnóstico , Neoplasias Meníngeas/patologia , Meningioma/diagnóstico , Meningioma/patologia , Tomografia Computadorizada por Raios XRESUMO
We report a new case of multiple trichoepitheliomas, milia and cylindromas syndrome. This new case differed from the others in that it was complicated by the occurrence of a basal cell carcinoma presenting as an ulcus rodens affecting the nasal pyramid. In such cases, the main differential diagnosis to be excluded is basal cell naevomatosis.
Assuntos
Carcinoma Adenoide Cístico/complicações , Dermatoses Faciais/complicações , Miliária/complicações , Neoplasias Primárias Múltiplas , Dermatoses do Couro Cabeludo/complicações , Neoplasias Cutâneas/complicações , Idoso , Carcinoma Adenoide Cístico/patologia , Carcinoma Basocelular/complicações , Carcinoma Basocelular/patologia , Dermatoses Faciais/patologia , Feminino , Humanos , Neoplasias Nasais/complicações , Neoplasias Nasais/patologia , Dermatoses do Couro Cabeludo/patologia , Neoplasias Cutâneas/patologia , SíndromeRESUMO
Hard plaques located in pressure areas were observed in an HIV-infected male patient at the AIDS stage. Histological examination of the skin showed necrosis of the eccrine sweat glands. The relationship between this disease and eccrine neutrophilic hidradenitis observed in HIV infection is discussed. The authors propose a concept of eccrine sweat gland lesion spectrum.
Assuntos
Síndrome da Imunodeficiência Adquirida/complicações , Úlcera Cutânea/etiologia , Doenças das Glândulas Sudoríparas/etiologia , Adulto , Diagnóstico Diferencial , Glândulas Écrinas , Hidradenite/patologia , Humanos , Masculino , Entorpecentes/intoxicação , Necrose , Úlcera Cutânea/patologia , Doenças das Glândulas Sudoríparas/patologiaRESUMO
INTRODUCTION: Headache opposite to a blue nevus of the scalp can reveal intra cranial melanotic lesions. CASE REPORT: A 25-year-old man caucasian was admitted to hospital for a first generalized tonic-clonic seizure. For six months, he has had episodic frontal-temporal right headache opposite to a blue pigmentary cutaneous congenital lesion in frontal territory (histology confirmed benign blue nevus). Neurologic examination noted a right congenital hereditary ophtalmoplegia. Cerebral MRI showed a right rolandic tumor with diffuse leptomeninge infiltration. This patient was operated of a meningeal melanocytoma with leptomeninges melanosis. DISCUSSION: The apparition of headache related to a blue nevus must lead to realize a cerebral MRI to look for a neuroectodermic hamartoma: melanotic tumor (in particular melanoma), or leptomeninges melanosis with high potential of degeneration. Meningeal melanocytoma is a rare benign spinal or intra cranial melanotic tumor.
Assuntos
Melanoma/patologia , Neoplasias Meníngeas/patologia , Segunda Neoplasia Primária/patologia , Nevo Azul/congênito , Couro Cabeludo , Neoplasias Cutâneas/congênito , Adulto , Biópsia , Epilepsia Tônico-Clônica/etiologia , Cefaleia/etiologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Melanoma/complicações , Melanoma/cirurgia , Neoplasias Meníngeas/complicações , Neoplasias Meníngeas/cirurgia , Segunda Neoplasia Primária/complicações , Segunda Neoplasia Primária/cirurgiaRESUMO
When interpreting smears and specimens, histologist and cytopathologists can be misled by images mimicking micro-organisms especially parasites such as protozoa, mycotic agents or helminths. Although some of these pitfalls are well-known, others can be problematic especially if nature of the contaminant is the same as that of the parasite that it mimics. False protozoa parasites can correspond either to exogenous agents such as spores, remnants of human cells, or inert exogenous particles. Pseudo-yeast images can be due to pollen, starch or soot but especially to cells such as macrophages, spermatozoids, and neurons or to various inert bodies such as pigments or calcifications. Pseudomycotic filaments can result from vegetable silk, asbestos bodies, radiate granules or fibrin. Curschmann's spirals and vegetable fibers can be confused with helminths and bacterial particles or pollen with helminth eggs.
Assuntos
Doenças Parasitárias/patologia , Doenças Parasitárias/parasitologia , Diagnóstico Diferencial , Técnicas de Preparação Histocitológica , HumanosRESUMO
Most publications devoted to diagnosis of helminths emphasize characteristic parasitological features. Histological feature are seldom described in detail. The purpose of this study was to propose a diagnostic method suitable for use by histologists who, unlike parasitologists, do not visualize the whole worm but rather pieces randomly scattered over a slide. It is relatively easy to distinguish helminths which have smooth muscle, no respiratory or circulatory system, and no coelom from arthropods which have striated muscle, both respiratory and circulatory systems, and coelom. At the adult stage, roundworms or nemathelminths present an external cuticle that may have patterned markings. The visceral cavity is empty. Adults can dwell either in the intestine in which case they are oviparous (oxyuris, ascaris, Ancylostoma, Strongyloides stercoralis, Trichuris...) or in tissue in which case they are viviparous (filaria). Larva of some species can be found in tissues. Adult tape-worms are devoid of cuticle and have a mesenchymatous visceral cavity. Cestodes which are segmented and have no digestive tract (taenias) are readily distinguishable from trematodes which are not segmented and have a digestive tract (faciolasis) Some cestodes unable thrive in man can cause cyst formation (hydatidosis, sparganosis, cysticercosis, coenurosis). On the basis of symptoms and histological features, it is usually possible to diagnose the genus and even the species of the offending helminth provided that the parasite has not been excessively damaged and that a sufficient number of sections are available.
Assuntos
Helmintíase/patologia , Helmintos/anatomia & histologia , Animais , Cestoides/anatomia & histologia , Nematoides/anatomia & histologia , Platelmintos/anatomia & histologia , Trematódeos/anatomia & histologiaRESUMO
Extensive bone marrow necrosis is a rare but severe complication of sickle cell disease. A formerly healthy man was admitted for bone pain, fever, and jaundice with severe aregenerative anemia. Bone marrow aspiration and biopsy showed extensive bone marrow necrosis while hemoglobin electrophoresis demonstrated homozygotic sickle cell disease. Despite early onset of septic arthritis of the right shoulder, outcome after blood transfusion and nonspecific treatment was favorable. Six months later, hemoglobin level remained stable up to 97 g/L. This first African case report illustrates typical features and good prognosis of extensive bone marrow necrosis in sickle cell disease. Extensive bone marrow necrosis is a highly unusual presenting manifestation of sickle cell in an adult.