Pesquisa | Secretaria de Estado da Saúde

1.

Predictors of bleeding and thrombotic events among patients admitted to the hospital with COVID-19 and elevated D-dimer: insights from the ACTION randomized clinical trial.

de Barros E Silva, Pedro Gabriel Melo; Furtado, Remo H M; de Alcântara Chaud, Mariana Silveira; Macedo, Ariane Vieira Scarlatelli; Bronhara, Bruna; Damiani, Lucas Petri; Barbosa, Lilian Mazza; Suiama, Mayra Akimi; Ramacciotti, Eduardo; de Aquino Martins, Priscilla; de Oliveira, Aryadne Lyrio; Nunes, Vinicius Santana; Ritt, Luiz Eduardo Fonteles; Rocha, Ana Thereza; Tramujas, Lucas; Santos, Sueli V; Diaz, Dario Rafael Abregu; Viana, Lorena Souza; Melro, Lívia Maria Garcia; Figueiredo, Estêvão Lanna; Neuenschwander, Fernando Carvalho; Dracoulakis, Marianna Deway Andrade; Lima, Rodolfo Godinho Souza Dourado; de Souza Dantas, Vicente Cés; Fernandes, Anne Cristine Silva; Gebara, Otávio Celso Eluf; Hernandes, Mauro Esteves; Queiroz, Diego Aparecido Rios; Veiga, Viviane C; Canesin, Manoel Fernandes; de Faria, Leonardo Meira; Feitosa-Filho, Gilson Soares; Gazzana, Marcelo Basso; Liporace, Idelzuíta Leandro; de Oliveira Twardowsky, Aline; Maia, Lilia Nigro; Machado, Flávia Ribeiro; de Matos Soeiro, Alexandre; Conceição-Souza, Germano Emílio; Armaganijan, Luciana; Guimarães, Patrícia O; Rosa, Regis G; Azevedo, Luciano C P; Alexander, John H; Avezum, Alvaro; Berwanger, Otávio; Cavalcanti, Alexandre B; Lopes, Renato D.

J Thromb Thrombolysis ; 2024 May 18.

Artigo Inglês | MEDLINE | ID: mdl-38762708

2.

Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve.

Guimarães, Helio P; Lopes, Renato D; de Barros E Silva, Pedro G M; Liporace, Idelzuita L; Sampaio, Roney O; Tarasoutchi, Flávio; Hoffmann-Filho, Conrado R; de Lemos Soares Patriota, Rodrigo; Leiria, Tiago L L; Lamprea, Diana; Precoma, Dalton B; Atik, Fernando A; Silveira, Fabio S; Farias, Fabio R; Barreto, Diogo O; Almeida, Adail P; Zilli, Alexandre C; de Souza Neto, João D; Cavalcante, Margaret A; Figueira, Fernando A M S; Kojima, Flávia C S; Damiani, Lucas; Santos, Renato H N; Valeis, Nanci; Campos, Viviane B; Saraiva, Jose F K; Fonseca, Francisco H; Pinto, Ibraim M; Magalhães, Carlos C; Ferreira, Joao F M; Alexander, John H; Pavanello, Ricardo; Cavalcanti, Alexandre B; Berwanger, Otavio.

N Engl J Med ; 383(22): 2117-2126, 2020 11 26.

Artigo Inglês | MEDLINE | ID: mdl-33196155

3.

Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19.

Cavalcanti, Alexandre B; Zampieri, Fernando G; Rosa, Regis G; Azevedo, Luciano C P; Veiga, Viviane C; Avezum, Alvaro; Damiani, Lucas P; Marcadenti, Aline; Kawano-Dourado, Letícia; Lisboa, Thiago; Junqueira, Debora L M; de Barros E Silva, Pedro G M; Tramujas, Lucas; Abreu-Silva, Erlon O; Laranjeira, Ligia N; Soares, Aline T; Echenique, Leandro S; Pereira, Adriano J; Freitas, Flávio G R; Gebara, Otávio C E; Dantas, Vicente C S; Furtado, Remo H M; Milan, Eveline P; Golin, Nicole A; Cardoso, Fábio F; Maia, Israel S; Hoffmann Filho, Conrado R; Kormann, Adrian P M; Amazonas, Roberto B; Bocchi de Oliveira, Monalisa F; Serpa-Neto, Ary; Falavigna, Maicon; Lopes, Renato D; Machado, Flávia R; Berwanger, Otavio.

N Engl J Med ; 383(21): 2041-2052, 2020 11 19.

Artigo Inglês | MEDLINE | ID: mdl-32706953

4.

Association between Type of Fluid Received Prior to Enrollment, Type of Admission, and Effect of Balanced Crystalloid in Critically Ill Adults: A Secondary Exploratory Analysis of the BaSICS Clinical Trial.

Zampieri, Fernando G; Machado, Flávia R; Biondi, Rodrigo S; Freitas, Flávio G R; Veiga, Viviane C; Figueiredo, Rodrigo C; Lovato, Wilson J; Amêndola, Cristina P; Serpa-Neto, Ary; Paranhos, Jorge L R; Lúcio, Eraldo A; Oliveira-Júnior, Lúcio C; Lisboa, Thiago C; Lacerda, Fábio H; Maia, Israel S; Grion, Cintia M C; Assunção, Murillo S C; Manoel, Airton L O; Corrêa, Thiago D; Guedes, Marco Antonio V A; Azevedo, Luciano C P; Miranda, Tamiris A; Damiani, Lucas P; Brandão da Silva, Nilton; Cavalcanti, Alexandre B.

Am J Respir Crit Care Med ; 205(12): 1419-1428, 2022 06 15.

Artigo Inglês | MEDLINE | ID: mdl-35349397

5.

Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial.

Lopes, Renato D; de Barros E Silva, Pedro Gabriel Melo; Furtado, Remo H M; Macedo, Ariane Vieira Scarlatelli; Bronhara, Bruna; Damiani, Lucas Petri; Barbosa, Lilian Mazza; de Aveiro Morata, Júlia; Ramacciotti, Eduardo; de Aquino Martins, Priscilla; de Oliveira, Aryadne Lyrio; Nunes, Vinicius Santana; Ritt, Luiz Eduardo Fonteles; Rocha, Ana Thereza; Tramujas, Lucas; Santos, Sueli V; Diaz, Dario Rafael Abregu; Viana, Lorena Souza; Melro, Lívia Maria Garcia; de Alcântara Chaud, Mariana Silveira; Figueiredo, Estêvão Lanna; Neuenschwander, Fernando Carvalho; Dracoulakis, Marianna Deway Andrade; Lima, Rodolfo Godinho Souza Dourado; de Souza Dantas, Vicente Cés; Fernandes, Anne Cristine Silva; Gebara, Otávio Celso Eluf; Hernandes, Mauro Esteves; Queiroz, Diego Aparecido Rios; Veiga, Viviane C; Canesin, Manoel Fernandes; de Faria, Leonardo Meira; Feitosa-Filho, Gilson Soares; Gazzana, Marcelo Basso; Liporace, Idelzuíta Leandro; de Oliveira Twardowsky, Aline; Maia, Lilia Nigro; Machado, Flávia Ribeiro; de Matos Soeiro, Alexandre; Conceição-Souza, Germano Emílio; Armaganijan, Luciana; Guimarães, Patrícia O; Rosa, Regis G; Azevedo, Luciano C P; Alexander, John H; Avezum, Alvaro; Cavalcanti, Alexandre B; Berwanger, Otavio.

Lancet ; 397(10291): 2253-2263, 2021 06 12.

Artigo Inglês | MEDLINE | ID: mdl-34097856

6.

Ventilatory Variables and Mechanical Power in Patients with Acute Respiratory Distress Syndrome.

Costa, Eduardo L V; Slutsky, Arthur S; Brochard, Laurent J; Brower, Roy; Serpa-Neto, Ary; Cavalcanti, Alexandre B; Mercat, Alain; Meade, Maureen; Morais, Caio C A; Goligher, Ewan; Carvalho, Carlos R R; Amato, Marcelo B P.

Am J Respir Crit Care Med ; 204(3): 303-311, 2021 08 01.

Artigo Inglês | MEDLINE | ID: mdl-33784486

7.

Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial.

Furtado, Remo H M; Berwanger, Otavio; Fonseca, Henrique A; Corrêa, Thiago D; Ferraz, Leonardo R; Lapa, Maura G; Zampieri, Fernando G; Veiga, Viviane C; Azevedo, Luciano C P; Rosa, Regis G; Lopes, Renato D; Avezum, Alvaro; Manoel, Airton L O; Piza, Felipe M T; Martins, Priscilla A; Lisboa, Thiago C; Pereira, Adriano J; Olivato, Guilherme B; Dantas, Vicente C S; Milan, Eveline P; Gebara, Otavio C E; Amazonas, Roberto B; Oliveira, Monalisa B; Soares, Ronaldo V P; Moia, Diogo D F; Piano, Luciana P A; Castilho, Kleber; Momesso, Roberta G R A P; Schettino, Guilherme P P; Rizzo, Luiz Vicente; Neto, Ary Serpa; Machado, Flávia R; Cavalcanti, Alexandre B.

Lancet ; 396(10256): 959-967, 2020 10 03.

Artigo Inglês | MEDLINE | ID: mdl-32896292

8.

Randomized clinical trial to evaluate a routine full anticoagulation Strategy in Patients with Coronavirus Infection (SARS-CoV2) admitted to hospital: Rationale and design of the ACTION (AntiCoagulaTlon cOroNavirus)-Coalition IV trial.

Lopes, Renato D; de Barros E Silva, Pedro Gabriel Melo; Furtado, Remo H M; Macedo, Ariane Vieira Scarlatelli; Ramacciotti, Eduardo; Damini, Lucas Petri; Bronhara, Bruna; Cavalcanti, Alexandre B; Rosa, Regis G; Azevedo, Luciano C P; Veiga, Viviane C; Machado, Flávia R; Ritt, Luiz Eduardo; Martins, Priscilla de Aquino; Alexander, John H; Avezum, Alvaro; Berwanger, Otavio.

Am Heart J ; 238: 1-11, 2021 08.

Artigo Inglês | MEDLINE | ID: mdl-33891907

9.

A randomized clinical trial to evaluate the efficacy and safety of rivaroxaban in patients with bioprosthetic mitral valve and atrial fibrillation or flutter: Rationale and design of the RIVER trial.

Guimarães, Helio P; de Barros E Silva, Pedro G M; Liporace, Idelzuita L; Sampaio, Roney O; Tarasoutchi, Flávio; Paixão, Milena; Hoffmann-Filho, Conrado R; Patriota, Rodrigo; Leiria, Tiago L L; Lamprea, Diana; Precoma, Dalton B; Atik, Fernando A; Silveira, Fabio S; Farias, Fabio R; Barreto, Diogo O; Almeida, Adail P; Zilli, Alexandre C; de Souza Neto, João D; Cavalcante, Margaret A; Figueira, Fernando A M S; Junior, Roque A; Moisés, Valdir A; Mesas, Cezar E; Ardito, Roberto V; Kalil, Paulo S A; Paiva, Maria S M O; Maldonado, Jaime G A; de Lima, Carlos E B; D'Oliveira Vieira, Ricardo; Laranjeira, Ligia; Kojima, Flávia; Damiani, Lucas; Nakagawa, Renato H; Dos Santos, Juliana R Y; Sampaio, Bruna S; Campos, Viviane B; Saraiva, Jose F K; Fonseca, Francisco H; Pinto, Ibraim M; Magalhães, Carlos C; Ferreira, Joao F M; Lopes, Renato D; Pavanello, Ricardo; Cavalcanti, Alexandre B; Berwanger, Otavio.

Am Heart J ; 231: 128-136, 2021 01.

Artigo Inglês | MEDLINE | ID: mdl-33045224

10.

Three-year effects of bariatric surgery on obstructive sleep apnea in patients with obesity grade 1 and 2: a sub-analysis of the GATEWAY trial.

Furlan, Sofia F; Drager, Luciano F; Santos, Renato Nakagawa; Damiani, Lucas P; Bersch-Ferreira, Angela Cristine; Miranda, Tamiris A; Machado, Rachel Helena V; Santucci, Eliana V; Bortolotto, Luiz A; Lorenzi-Filho, Geraldo; Berwanger, Otavio; Cavalcanti, Alexandre B; Schiavon, Carlos A.

Int J Obes (Lond) ; 45(4): 914-917, 2021 04.

Artigo Inglês | MEDLINE | ID: mdl-33589771

11.

Effects of a Resuscitation Strategy Targeting Peripheral Perfusion Status versus Serum Lactate Levels among Patients with Septic Shock. A Bayesian Reanalysis of the ANDROMEDA-SHOCK Trial.

Zampieri, Fernando G; Damiani, Lucas P; Bakker, Jan; Ospina-Tascón, Gustavo A; Castro, Ricardo; Cavalcanti, Alexandre B; Hernandez, Glenn.

Am J Respir Crit Care Med ; 201(4): 423-429, 2020 02 15.

Artigo Inglês | MEDLINE | ID: mdl-31574228

12.

Predictive Accuracy of the Quick Sepsis-related Organ Failure Assessment Score in Brazil. A Prospective Multicenter Study.

Machado, Flavia R; Cavalcanti, Alexandre B; Monteiro, Mariana B; Sousa, Juliana L; Bossa, Aline; Bafi, Antonio T; Dal-Pizzol, Felipe; Freitas, Flavio G R; Lisboa, Thiago; Westphal, Glauco A; Japiassu, Andre M; Azevedo, Luciano C P.

Am J Respir Crit Care Med ; 201(7): 789-798, 2020 04 01.

Artigo Inglês | MEDLINE | ID: mdl-31910037

13.

Three-Year Outcomes of Bariatric Surgery in Patients With Obesity and Hypertension : A Randomized Clinical Trial.

Schiavon, Carlos A; Bhatt, Deepak L; Ikeoka, Dimas; Santucci, Eliana V; Santos, Renato Nakagawa; Damiani, Lucas P; Oliveira, Juliana D; Machado, Rachel Helena V; Halpern, Helio; Monteiro, Frederico L J; Noujaim, Patricia M; Cohen, Ricardo V; de Souza, Marcio G; Amodeo, Celso; Bortolotto, Luiz A; Berwanger, Otavio; Cavalcanti, Alexandre B; Drager, Luciano F.

Ann Intern Med ; 173(9): 685-693, 2020 11 03.

Artigo Inglês | MEDLINE | ID: mdl-32805133

14.

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19: A Randomized Clinical Trial.

Ospina-Tascón, Gustavo A; Calderón-Tapia, Luis Eduardo; García, Alberto F; Zarama, Virginia; Gómez-Álvarez, Freddy; Álvarez-Saa, Tatiana; Pardo-Otálvaro, Stephania; Bautista-Rincón, Diego F; Vargas, Mónica P; Aldana-Díaz, José L; Marulanda, Ángela; Gutiérrez, Alejandro; Varón, Janer; Gómez, Mónica; Ochoa, María E; Escobar, Elena; Umaña, Mauricio; Díez, Julio; Tobón, Gabriel J; Albornoz, Ludwig L; Celemín Flórez, Carlos Augusto; Ruiz, Guillermo Ortiz; Cáceres, Eder Leonardo; Reyes, Luis Felipe; Damiani, Lucas Petri; Cavalcanti, Alexandre B.

JAMA ; 326(21): 2161-2171, 2021 Dec 07.

Artigo Inglês | MEDLINE | ID: mdl-34874419

15.

Effect of Slower vs Faster Intravenous Fluid Bolus Rates on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial.

Zampieri, Fernando G; Machado, Flávia R; Biondi, Rodrigo S; Freitas, Flávio G R; Veiga, Viviane C; Figueiredo, Rodrigo C; Lovato, Wilson J; Amêndola, Cristina P; Assunção, Murillo S C; Serpa-Neto, Ary; Paranhos, Jorge L R; Andrade, José; Godoy, Michele M G; Romano, Edson; Dal Pizzol, Felipe; Silva, Emerson B; Silva, Miqueias M L; Machado, Miriam C V; Malbouisson, Luiz Marcelo S; Manoel, Airton L O; Thompson, Marlus M; Figueiredo, Lanese M; Soares, Rafael M; Miranda, Tamiris A; de Lima, Lucas M; Santucci, Eliana V; Corrêa, Thiago D; Azevedo, Luciano C P; Kellum, John A; Damiani, Lucas P; Silva, Nilton B; Cavalcanti, Alexandre B.

JAMA ; 326(9): 830-838, 2021 09 07.

Artigo Inglês | MEDLINE | ID: mdl-34547081

16.

Effect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial.

Zampieri, Fernando G; Machado, Flávia R; Biondi, Rodrigo S; Freitas, Flávio G R; Veiga, Viviane C; Figueiredo, Rodrigo C; Lovato, Wilson J; Amêndola, Cristina P; Serpa-Neto, Ary; Paranhos, Jorge L R; Guedes, Marco A V; Lúcio, Eraldo A; Oliveira-Júnior, Lúcio C; Lisboa, Thiago C; Lacerda, Fábio H; Maia, Israel S; Grion, Cintia M C; Assunção, Murillo S C; Manoel, Airton L O; Silva-Junior, João M; Duarte, Péricles; Soares, Rafael M; Miranda, Tamiris A; de Lima, Lucas M; Gurgel, Rodrigo M; Paisani, Denise M; Corrêa, Thiago D; Azevedo, Luciano C P; Kellum, John A; Damiani, Lucas P; Brandão da Silva, Nilton; Cavalcanti, Alexandre B.

JAMA ; 2021 Aug 10.

Artigo Inglês | MEDLINE | ID: mdl-34375394

17.

From Berlin to Global: The Need for Syndromic Definitions of Acute Respiratory Distress Syndrome.

Alipanah-Lechner, Narges; Cavalcanti, Alexandre B; Diaz, Janet; Ferguson, Niall D; Myatra, Sheila N; Calfee, Carolyn S.

Am J Respir Crit Care Med ; 209(1): 21-23, 2024 Jan 01.

Artigo Inglês | MEDLINE | ID: mdl-37816094

18.

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis.

Sterne, Jonathan A C; Murthy, Srinivas; Diaz, Janet V; Slutsky, Arthur S; Villar, Jesús; Angus, Derek C; Annane, Djillali; Azevedo, Luciano Cesar Pontes; Berwanger, Otavio; Cavalcanti, Alexandre B; Dequin, Pierre-Francois; Du, Bin; Emberson, Jonathan; Fisher, David; Giraudeau, Bruno; Gordon, Anthony C; Granholm, Anders; Green, Cameron; Haynes, Richard; Heming, Nicholas; Higgins, Julian P T; Horby, Peter; Jüni, Peter; Landray, Martin J; Le Gouge, Amelie; Leclerc, Marie; Lim, Wei Shen; Machado, Flávia R; McArthur, Colin; Meziani, Ferhat; Møller, Morten Hylander; Perner, Anders; Petersen, Marie Warrer; Savovic, Jelena; Tomazini, Bruno; Veiga, Viviane C; Webb, Steve; Marshall, John C.

JAMA ; 324(13): 1330-1341, 2020 10 06.

Artigo Inglês | MEDLINE | ID: mdl-32876694

19.

Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial.

Tomazini, Bruno M; Maia, Israel S; Cavalcanti, Alexandre B; Berwanger, Otavio; Rosa, Regis G; Veiga, Viviane C; Avezum, Alvaro; Lopes, Renato D; Bueno, Flavia R; Silva, Maria Vitoria A O; Baldassare, Franca P; Costa, Eduardo L V; Moura, Ricardo A B; Honorato, Michele O; Costa, Andre N; Damiani, Lucas P; Lisboa, Thiago; Kawano-Dourado, Letícia; Zampieri, Fernando G; Olivato, Guilherme B; Righy, Cassia; Amendola, Cristina P; Roepke, Roberta M L; Freitas, Daniela H M; Forte, Daniel N; Freitas, Flávio G R; Fernandes, Caio C F; Melro, Livia M G; Junior, Gedealvares F S; Morais, Douglas Costa; Zung, Stevin; Machado, Flávia R; Azevedo, Luciano C P.

JAMA ; 324(13): 1307-1316, 2020 10 06.

Artigo Inglês | MEDLINE | ID: mdl-32876695

20.

Hydroxychloroquine with or without Azithromycin in Covid-19. Reply.

Cavalcanti, Alexandre B; Berwanger, Otávio; Zampieri, Fernando G.

N Engl J Med ; 384(2): 191, 2021 01 14.

Artigo Inglês | MEDLINE | ID: mdl-33264542

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