Detalhe da pesquisa
1.
Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT).
Bioorg Med Chem
; 41: 116216, 2021 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34023664
2.
Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry.
Bioorg Med Chem
; 42: 116223, 2021 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34091303
3.
Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical Library.
Chembiochem
; 18(9): 864-871, 2017 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28056160
4.
Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.
ACS Infect Dis
; 10(5): 1561-1575, 2024 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38577994
5.
Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen.
J Med Chem
; 67(4): 3039-3065, 2024 Feb 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38306405
6.
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds.
J Med Chem
; 67(8): 6456-6494, 2024 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38574366
7.
Metabolites of PPI-2458, a selective, irreversible inhibitor of methionine aminopeptidase-2: structure determination and in vivo activity.
Drug Metab Dispos
; 41(4): 814-26, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23355637
8.
Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning.
J Med Chem
; 66(23): 16051-16061, 2023 12 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37996079
9.
Corrigendum: Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNAEncoded Chemical Library.
Chembiochem
; 18(24): 2441, 2017 12 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29239533
10.
Design, synthesis and selection of DNA-encoded small-molecule libraries.
Nat Chem Biol
; 5(9): 647-54, 2009 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-19648931
11.
Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa.
J Med Chem
; 64(19): 14377-14425, 2021 10 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34569791
12.
Antiparasitic activities of novel, orally available fumagillin analogs.
Bioorg Med Chem Lett
; 19(17): 5128-31, 2009 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19648008
13.
Development and Synthesis of DNA-Encoded Benzimidazole Library.
ACS Comb Sci
; 20(5): 251-255, 2018 05 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29648439
14.
Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.
Nat Commun
; 9: 16227, 2018 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-30004092
15.
Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.
ACS Med Chem Lett
; 8(2): 239-244, 2017 Feb 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28197319
16.
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action.
ACS Chem Biol
; 12(11): 2730-2736, 2017 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29043777
17.
Correction to "Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors".
ACS Med Chem Lett
; 8(11): 1204, 2017 11 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29152055
18.
Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.
Nat Commun
; 8: 16081, 2017 07 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28714473
19.
Design and Synthesis of Biaryl DNA-Encoded Libraries.
ACS Comb Sci
; 18(10): 625-629, 2016 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27571034
20.
Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor.
ACS Comb Sci
; 17(12): 722-31, 2015 Dec 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26562224