RESUMO
A thoracic paravertebral mass in an asymptomatic woman with type 1 Gaucher's disease proved to be due to extramedullary hematopoiesis. This is, to our knowledge, the first case of intrathoracic extramedullary hematopoiesis reported with Gaucher's disease.
Assuntos
Doença de Gaucher/complicações , Hematopoese Extramedular , Tórax , Idoso , Feminino , Doença de Gaucher/diagnóstico por imagem , Doença de Gaucher/fisiopatologia , Humanos , Radiografia Torácica , Tomografia Computadorizada por Raios XRESUMO
RATIONALE AND OBJECTIVES: The authors tested the hypothesis that changes in oxygen saturation (%HbO2) in the superior mesenteric vein (SMV), as measured with in vivo magnetic resonance (MR) oximetry, correlate with the degree of acute superior mesenteric artery (SMA) flow reduction. METHODS: Ten mongrel dogs were studied. A catheter was inserted into the SMV, and a perivascular ultrasonic flow probe and an adjustable mechanical occluder were placed around the SMA. MR oximetry was carried out at the resting state and after the SMA was constricted to predetermined levels (0%-75% of initial flow). In seven dogs, SMV blood samples were obtained immediately before and after each MR measurement; %HbO2 was measured simultaneously by using an oximeter. With linear regression analysis, the SMV %HbO2 measurements obtained at MR imaging were compared with those obtained at oximetry. With a logistic model, MR imaging changes in SMV %HbO2 were compared with the degree of SMA flow reduction. RESULTS: SMV %HbO2 measurements obtained with MR imaging correlated well with those obtained with oximetry (r = .97). Changes in SMV %HbO2 measured at MR imaging also correlated well with the degree of SMA flow reduction, as determined with a logistic model (P = .01). CONCLUSION: Noninvasive in vivo MR measurements of SMV %HbO2 can be used to determine the degree of acute SMA flow reduction with a high degree of accuracy in a canine model.
Assuntos
Veias Mesentéricas/fisiologia , Oxigênio/sangue , Animais , Cães , Isquemia/fisiopatologia , Modelos Logísticos , Angiografia por Ressonância Magnética , Veias Mesentéricas/fisiopatologia , Oximetria/métodos , Fluxo Sanguíneo RegionalRESUMO
OBJECTIVE: The purpose of this study was to determine whether recently described criteria, including hyperintense T2-weighted signal or other abnormalities revealed by MR imaging within deep fascial planes, are specific for necrotizing soft-tissue infections. MATERIALS AND METHODS: We reviewed 22 MR imaging examinations that revealed abnormally high signal intensity within deep fascial planes on T2-weighted images. Twenty-one of the patients had clinical diagnoses other than necrotizing soft-tissue infection, including nonnecrotizing cellulitis (n = 4), abscess without evidence of necrotizing fasciitis (n = 5), and cellulitis with accompanying vascular thrombosis (n = 2). MR imaging was performed using T1-weighted spin-echo (range of TRs/range of TEs, 300-800/9-30) and fat-saturated T2-weighted fast spin-echo (3000-5000/76-108) sequences. Gadolinium-enhanced T1-weighted spin-echo MR images with fat saturation were obtained for 14 patients. Two reviewers, unaware of clinical diagnoses, evaluated each study for abnormalities in superficial and deep soft tissues and submitted a consensus diagnosis. RESULTS: Using only the described MR imaging criteria, we interpreted all cases as necrotizing cellulitis, including the cases of 21 patients who had nonnecrotizing conditions. CONCLUSION: Hyperintense T2-weighted signal within deep fascial planes and muscle, with or without contrast enhancement, is not specific for necrotizing soft-tissue infection. A variety of conditions exhibited similar findings and were indistinguishable from necrotizing soft-tissue infection.
Assuntos
Celulite (Flegmão)/diagnóstico , Fasciite Necrosante/diagnóstico , Imageamento por Ressonância Magnética/métodos , Infecções dos Tecidos Moles/diagnóstico , Adulto , Meios de Contraste , Diagnóstico Diferencial , Fáscia/patologia , Feminino , Gadolínio , Humanos , Masculino , Estudos RetrospectivosRESUMO
We report two cases of scrotal cystocele. In patients suspected of having a scrotal cystocele, we believe that ultrasonography is the initial examination of choice. Emptying of a scrotal cystocele with voiding is an important diagnostic feature. Failure to show a direct communication between the bladder and scrotal cystocele with ultrasonography should not exclude the diagnosis. Scrotal cystocele should be considered in the differential diagnosis of the fluidfilled scrotum. The preoperative detection of massive inguinoscrotal bladder herniation is important to avoid bladder injury during herniorrhaphy.
Assuntos
Escroto/diagnóstico por imagem , Doenças da Bexiga Urinária/diagnóstico por imagem , Idoso , Hérnia/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , UltrassonografiaRESUMO
PURPOSE: To determine if dogs and humans with chronic mesenteric ischemia demonstrate a decrease in the percentage of oxygenated hemoglobin (%HbO2) in the superior mesenteric vein (SMV) after a meal. MATERIALS AND METHODS: In 10 dogs, ameroid rings were surgically implanted around the superior mesenteric arteries to create gradual stenosis. Pre- and postoperative angiograms and pre- and postprandial magnetic resonance (MR) oximetry measurements of the SMV %HbO2, with flow-independent T2 measurements of venous blood, were obtained at different times. In 10 patients with atherosclerotic disease and six patients with symptomatic chronic mesenteric ischemia, the same measurements were obtained after at least 6 hours of fasting and at 15, 35, and 45 minutes after ingestion of a liquid nutritional supplement. RESULTS: In seven dogs, the postprandial SMV %HbO2 increased an average of 2.5% +/- 0.8 before surgery and decreased an average of 6.3% +/- 2.1 when hemodynamically significant (>70%) stenosis of the superior mesenteric artery developed 7-14 days after surgery. In the 10 patients without ischemia, the SMV %HbO2 increased by 4.6% +/- 0.6, whereas in the symptomatic patients a postprandial decrease of 8.8% +/- 0.7 occurred (P < .0001). CONCLUSION: Measurement of the SMV %HbO2 with MR oximetry is a promising test for diagnosis of chronic mesenteric ischemia.
Assuntos
Ingestão de Alimentos , Angiografia por Ressonância Magnética , Oclusão Vascular Mesentérica/diagnóstico , Oclusão Vascular Mesentérica/metabolismo , Oxiemoglobinas/metabolismo , Adulto , Idoso , Idoso de 80 Anos ou mais , Animais , Estudos de Casos e Controles , Doença Crônica , Cães , Jejum , Feminino , Seguimentos , Humanos , Masculino , Artérias Mesentéricas , Oclusão Vascular Mesentérica/cirurgia , Veias Mesentéricas , Pessoa de Meia-Idade , Oximetria , Fatores de TempoRESUMO
PURPOSE: Virtual colonoscopy is a new method of colon examination in which computer-aided 3D visualization of spiral CT simulates fiberoptic colonoscopy. We used a colon phantom containing various-sized spheres to determine the influence of CT acquisition parameters on lesion detectability and sizing. METHOD: Spherical plastic beads with diameters of 2.5, 4, 6, 8 and 10 mm were randomly attached to the inner wall of segments of plastic tubing. Groups of three sealed tubes were scanned at 3/1, 3/2, 5/1 collimation (mm)/pitch settings in orientations perpendicular and parallel to the scanner gantry. For each acquisition, image sets were reconstructed at intervals from 0.5 to 5.0 mm. Two blinded reviewers assessed transverse cross-sections of the phantoms for bead detection, using source CT images for images for acquisitions obtained with the tubes oriented perpendicular to the gantry and using orthogonal reformatted images for scans oriented parallel to the gantry. RESULTS: Detection of beads of > or = 4 mm was 100% for both tube orientations and for all collimator/pitch settings and reconstruction intervals. For the 2.5 mm beads, detection decreased to 78-94% for 5 mm collimation/pitch 2 scans when the phantom sections were oriented parallel to the gantry (p = 0.01). Apparent elongation of beads in the slice direction occurred as the collimation and pitch increased. The majority of the elongation (approximately 75%) was attributable to changing the collimator from 3 to 5 mm, with the remainder of the elongation due to doubling the pitch from 1 to 2. CONCLUSION: CT scanning at 5 mm collimation and up to pitch 2 is adequate for detection of high contrast lesions as small as 4 mm in this model. However, lesion size and geometry are less accurately depicted than at narrower collimation and lower pitch settings.
Assuntos
Pólipos do Colo/diagnóstico , Colonoscopia/métodos , Imagens de Fantasmas , Interface Usuário-Computador , Colo/diagnóstico por imagem , Colonoscopia/estatística & dados numéricos , Intervalos de Confiança , Desenho de Equipamento , Tecnologia de Fibra Óptica , Humanos , Imagens de Fantasmas/estatística & dados numéricos , Distribuição de Poisson , Sensibilidade e Especificidade , Tomografia Computadorizada por Raios X/métodos , Tomografia Computadorizada por Raios X/estatística & dados numéricosRESUMO
OBJECTIVE: Our objective was to evaluate the accuracy of MR imaging strategy that uses primarily fast spin-echo sequences for the diagnosis of anterior cruciate ligament tears. MATERIALS AND METHODS: The original clinical interpretations of MR images of 217 examinations of the knee joint were correlated with subsequent arthroscopic results. Each MR examination included a double-echo fast spin-echo sequence as the only imaging sequence in the sagittal plane. Subsequent discordant MR and arthroscopic examinations were then subjected to reanalysis by two observers who were unaware of arthroscopic results to determine if misinterpretations were observer or image dependent. Two hundred sixteen patients who underwent MR imaging for suspected internal derangement of the knee subsequently underwent arthroscopic surgery. Two patients had both knees evaluated. One patient was excluded because he was referred for evaluation for osteomyelitis, not internal derangement. This yielded a total number of 217 MR examinations for suspected internal derangement of the knee. RESULTS: For 56 arthroscopically proven tears, the sensitivity of MR imaging was 96%. The specificity was 98%, yielding an overall accuracy rate of 98%. The positive and negative predictive values were 95% and 99%, respectively. These values are within the ranges of previously reported MR imaging strategies using conventional spin-echo sequences. CONCLUSION: Fast spin-echo MR imaging of the knee can be an alternative to conventional spin-echo imaging for the detection of anterior cruciate ligament tears.
Assuntos
Lesões do Ligamento Cruzado Anterior , Artroscopia , Aumento da Imagem/métodos , Imageamento por Ressonância Magnética/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Ligamento Cruzado Anterior/patologia , Criança , Feminino , Humanos , Luxações Articulares/diagnóstico , Luxações Articulares/patologia , Traumatismos do Joelho/diagnóstico , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Osteomielite/diagnóstico , Valor Preditivo dos Testes , Ruptura , Sensibilidade e Especificidade , Método Simples-Cego , Entorses e Distensões/diagnóstico , Entorses e Distensões/patologiaRESUMO
PURPOSE: We assessed the utility of power Doppler imaging (PDI) in preoperative planning and postoperative evaluation of microvascular tissue transfers. METHODS: Twenty-five PDI studies were performed on 23 patients using a 5-10-MHz linear-array transducer. Thirteen patients were assessed preoperatively for patency of the desired donor vessel; 8 of them had surgical scars overlying the desired vascular territory. Twelve patients (including 2 from the first group) were evaluated postoperatively for patency of the vascular anastomoses and adequacy of the blood supply to the transferred tissue. RESULTS: Twelve of the 13 patients assessed preoperatively had successful flap transfers. Four of the 8 patients with scars over the desired vascular territories had absent or aberrant arteries, necessitating a change in the operative plan. None of these patients had operative complications. Eight of the 12 patients scanned postoperatively had patent anastomoses. In 2 of these patients, impending surgery was averted when the adequacy of the tissue blood supply was established with PDI. In 4 patients, PDI showed arterial or venous compromise, which was confirmed at surgery. CONCLUSIONS: PDI is a useful technique in microsurgical tissue transfer for assessing the patency of desired donor vessels preoperatively and for postoperative evaluation of blood supply.
Assuntos
Artérias Epigástricas/diagnóstico por imagem , Cuidados Pós-Operatórios/métodos , Cuidados Pré-Operatórios/métodos , Retalhos Cirúrgicos/irrigação sanguínea , Ultrassonografia Doppler , Adulto , Idoso , Velocidade do Fluxo Sanguíneo , Cicatriz/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Monitorização Fisiológica , Valor Preditivo dos Testes , Estudos Prospectivos , Procedimentos de Cirurgia Plástica/métodos , Reto do Abdome/irrigação sanguínea , Reto do Abdome/cirurgiaRESUMO
The purpose of this study was to examine hepatic lesions with a sequence designed to yield improved T2 measurements and evaluate the clinical utility of these measurements in distinguishing malignant from benign disease. Using a modified Carr-Purcell sequence incorporating features designed to compensate for imperfections in the imaging system, including a train of refocusing pulses emitted in an MLEV pattern oriented in composite fashion along all three coordinate axes, and a single spatially selective pulse placed immediately before a spiral readout, 14 benign lesions and 13 malignant lesions were evaluated prospectively with a conventional 1.5 T imager. The maximum, minimum, and mean T2 values of malignant lesions, hemangiomas, and cysts exceeded corresponding published values from spin-echo and echoplanar studies. The mean T2 value of the malignant lesions differed significantly (P < 0.0001) from those of hemangiomas and cysts. All malignant lesions and all benign lesions were distinguishable by their T2 values, which had ranges of no greater than 118.6 msec and no less than 134.3 msec, respectively. This early experience suggests that improved T2 measurements can facilitate the differentiation of hepatic malignancies from hemangiomas and cysts.
Assuntos
Cistos/diagnóstico , Hemangioma/diagnóstico , Neoplasias Hepáticas/diagnóstico , Imageamento por Ressonância Magnética/métodos , Carcinoma Hepatocelular/diagnóstico , Diagnóstico Diferencial , Humanos , Hepatopatias/diagnóstico , Neoplasias Hepáticas/secundário , Estudos ProspectivosRESUMO
Our goal was to determine if arterial phase images from dual phase helical CT improve either the detection or the characterization of hepatic metastases in patients with colorectal carcinoma. Sixty-two patients with known colorectal cancer underwent 65 dual phase helical CT examinations to evaluate for possible liver metastases. Three blinded reviewers independently evaluated the portal venous phase images alone to determine if hepatic metastases were present or absent. Arterial phase images were then analyzed to determine if they identified additional lesions or aided in characterizing small hepatic lesions. Scores of the two methods for diagnosing metastases were compared with the "gold standard" established by a consensus panel of three other radiologists who reviewed all images together with clinical, pathologic, and other imaging data. The addition of arterial phase imaging did not detect any new metastases. However, in 6 of the 64 technically adequate examinations, hepatic arterial phase images increased lesion conspicuity and significantly increased diagnostic confidence when compared with portal vein phase scans alone. In patients with colorectal cancer, the addition of arterial phase imaging does not increase sensitivity, but improves the specificity in diagnosing liver metastases in a small number of cases. Dual phase helical CT does not appear to be indicated in the evaluation of liver metastases from colorectal cancer.