Detalhe da pesquisa
1.
Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency.
Nat Immunol
; 25(5): 764-777, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38609546
2.
Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis.
Nat Immunol
; 21(8): 857-867, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32601469
3.
Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS.
Nat Immunol
; 17(8): 914-21, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27270401
4.
Control of the innate immune response by the mevalonate pathway.
Nat Immunol
; 17(8): 922-9, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27270400
5.
Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.
Nature
; 577(7788): 103-108, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31827281
6.
Interrupting an IFN-γ-dependent feedback loop in the syndrome of pyogenic arthritis with pyoderma gangrenosum and acne.
Ann Rheum Dis
; 83(6): 787-798, 2024 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38408849
7.
Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever.
J Allergy Clin Immunol
; 152(1): 230-243, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36822481
8.
Galantamine attenuates autoinflammation in a mouse model of familial mediterranean fever.
Mol Med
; 28(1): 148, 2022 12 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36494621
9.
Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1ß activation and severe autoinflammation in mice.
Immunity
; 34(5): 755-68, 2011 May 27.
Artigo
Inglês
| MEDLINE | ID: mdl-21600797
10.
NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy.
Proc Natl Acad Sci U S A
; 114(37): E7766-E7775, 2017 09 12.
Artigo
Inglês
| MEDLINE | ID: mdl-28847925
11.
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease.
Proc Natl Acad Sci U S A
; 113(36): 10127-32, 2016 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27559085
12.
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.
Nature
; 492(7427): 123-7, 2012 Dec 06.
Artigo
Inglês
| MEDLINE | ID: mdl-23143333
13.
Early-onset stroke and vasculopathy associated with mutations in ADA2.
N Engl J Med
; 370(10): 911-20, 2014 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-24552284
14.
Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.
J Immunol
; 194(11): 5472-5487, 2015 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25917098
15.
The inflammasome pyrin contributes to pertussis toxin-induced IL-1ß synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis.
PLoS Pathog
; 10(5): e1004150, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24875775
16.
The systemic autoinflammatory diseases: Coming of age with the human genome.
J Allergy Clin Immunol
; 146(5): 997-1001, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32987090
17.
Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases.
J Allergy Clin Immunol
; 136(5): 1337-45, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26025129
18.
Microarray-based gene expression profiling in patients with cryopyrin-associated periodic syndromes defines a disease-related signature and IL-1-responsive transcripts.
Ann Rheum Dis
; 72(6): 1064-70, 2013 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-23223423
19.
Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome.
Proc Natl Acad Sci U S A
; 107(21): 9801-6, 2010 May 25.
Artigo
Inglês
| MEDLINE | ID: mdl-20457915
20.
Excess Serum Interleukin-18 Distinguishes Patients With Pathogenic Mutations in PSTPIP1.
Arthritis Rheumatol
; 74(2): 353-357, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34492165