Detalhe da pesquisa
1.
Improved Durability to SARS-CoV-2 Vaccine Immunity following Coimmunization with Molecular Adjuvant Adenosine Deaminase-1.
J Immunol
; 209(1): 118-127, 2022 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35750334
2.
Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators.
Retrovirology
; 18(1): 31, 2021 10 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34627310
3.
Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer.
Biochemistry
; 55(44): 6100-6114, 2016 Nov 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27731975
4.
Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist.
Acc Chem Res
; 47(4): 1228-37, 2014 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24502450
5.
Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancy.
Biochemistry
; 53(21): 3403-14, 2014 Jun 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24801282
6.
Abasic phosphorothioate oligomers inhibit HIV-1 reverse transcription and block virus transmission across polarized ectocervical organ cultures.
Antimicrob Agents Chemother
; 58(12): 7056-71, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25224013
7.
A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption.
Biochemistry
; 52(13): 2245-61, 2013 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-23470147
8.
Monoclonal antibody m18 paratope leading to dual receptor antagonism of HIV-1 gp120.
Biochemistry
; 50(14): 2769-79, 2011 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-21417283
9.
Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18.
Biochemistry
; 50(14): 2756-68, 2011 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-21351734
10.
Peptide Triazole Thiol Irreversibly Inactivates Metastable HIV-1 Env by Accessing Conformational Triggers Intrinsic to Virus-Cell Entry.
Microorganisms
; 9(6)2021 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34204725
11.
Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120.
Anal Bioanal Chem
; 396(3): 1143-52, 2010 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-20016882
12.
Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm.
Curr Protein Pept Sci
; 5(1): 1-8, 2004 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-14965316
13.
Peptide-small molecule hybrids via orthogonal deprotection-chemoselective conjugation to cysteine-anchored scaffolds. A model study.
Org Lett
; 4(23): 4041-4, 2002 Nov 14.
Artigo
Inglês
| MEDLINE | ID: mdl-12423081
14.
Non-natural peptide triazole antagonists of HIV-1 envelope gp120.
ChemMedChem
; 8(2): 322-8, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23239505
15.
Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120.
J Mol Recognit
; 22(2): 169-74, 2009.
Artigo
Inglês
| MEDLINE | ID: mdl-18498083
16.
Interleukin-5 receptor subunit oligomerization and rearrangement revealed by fluorescence resonance energy transfer imaging.
J Biol Chem
; 283(19): 13398-406, 2008 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-18326494
17.
Broad-spectrum anti-human immunodeficiency virus (HIV) potential of a peptide HIV type 1 entry inhibitor.
J Virol
; 81(7): 3645-8, 2007 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-17251295
18.
Recombinant-protein production in insect cells utilizing a hollow-fibre bioreactor.
Biotechnol Appl Biochem
; 45(Pt 3): 167-72, 2006 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-16872272
19.
Real-time monitoring of the membrane-binding and insertion properties of the cholesterol-dependent cytolysin anthrolysin O from Bacillus anthracis.
J Mol Recognit
; 19(4): 354-62, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-16775845
20.
Interaction with CD4 and antibodies to CD4-induced epitopes of the envelope gp120 from a microglial cell-adapted human immunodeficiency virus type 1 isolate.
J Virol
; 79(11): 6703-13, 2005 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-15890908