1.
Int J Biol Macromol
; 121: 643-649, 2019 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30339993
RESUMO
In this study, a new alkaloid was isolated from methanolic extract of Coccinea cordifolia root using flash chromatography and was subjected to spectral analysis like 1H NMR, 13C NMR, FTIR analysis and GCMS for confirming the structure of the isolated alkaloid. The isolated alkaloid was also subjected to immunomodulatory assays to verify its role in the claims against the plant. It was found that the isolated compound at a dose of 2.5â¯mg/kg has shown competitive immunomodulatory potential when evaluated by carbon clearance, delayed type hypersensitivity and haemagglutination titer models and using Levamisole at a dose of 50â¯mg/kg as the standard drug.