Detalhe da pesquisa
1.
Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation.
Proc Natl Acad Sci U S A
; 121(1): e2307086120, 2024 Jan 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38147543
2.
IL-23 regulation of myeloid cell biology during inflammation.
Cytokine
; 179: 156619, 2024 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38669908
3.
An Association between OXPHOS-Related Gene Expression and Malignant Hyperthermia Susceptibility in Human Skeletal Muscle Biopsies.
Int J Mol Sci
; 25(6)2024 Mar 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38542460
4.
Comparison of Transcriptomic Changes in Survivors of Exertional Heat Illness with Malignant Hyperthermia Susceptible Patients.
Int J Mol Sci
; 24(22)2023 Nov 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38003313
5.
Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia.
J Biol Chem
; 295(45): 15226-15235, 2020 11 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32826313
6.
Heteroarylureas with fused bicyclic diamine cores as inhibitors of fatty acid amide hydrolase.
Bioorg Med Chem Lett
; 30(20): 127463, 2020 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32784090
7.
Anti-MDA5-associated dermatomyositis.
Intern Med J
; 50(4): 484-487, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32270621
8.
Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals.
Br J Anaesth
; 122(5): 613-621, 2019 May.
Artigo
Inglês
| MEDLINE | ID: mdl-30916033
9.
A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors.
J Biol Chem
; 291(24): 12724-12731, 2016 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27129215
10.
Unravelling the unseen metabolic changes in patients with malignant hyperthermia.
Can J Anaesth
; 68(6): 751-754, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33532996
11.
Safety of stereotactic laser ablations performed as treatment for glioblastomas in a conventional magnetic resonance imaging suite.
Neurosurg Focus
; 41(4): E7, 2016 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-27690648
12.
Stereotactic laser ablation as treatment for brain metastases that recur after stereotactic radiosurgery: a multiinstitutional experience.
Neurosurg Focus
; 41(4): E11, 2016 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-27690654
13.
Phenotyping drug polypharmacology via eicosanoid profiling of blood.
J Lipid Res
; 56(8): 1492-500, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26022804
14.
Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase.
Bioorg Med Chem Lett
; 24(3): 737-41, 2014 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24433863
15.
1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.
Bioorg Med Chem Lett
; 24(5): 1280-4, 2014 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24513048
16.
Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
J Med Chem
; 65(21): 14326-14336, 2022 11 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36314537
17.
Discovery of a Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase with Oral Anti-Inflammatory Activity.
ACS Med Chem Lett
; 12(5): 782-790, 2021 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34055226
18.
Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase.
Anesth Analg
; 108(1): 316-29, 2009 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19095868
19.
Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH).
Bioorg Med Chem Lett
; 18(6): 2109-13, 2008 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18289847
20.
Real-time Magnetic Resonance Imaging-Guided Biopsy Using SmartFrame® Stereotaxis in the Setting of a Conventional Diagnostic Magnetic Resonance Imaging Suite.
Oper Neurosurg (Hagerstown)
; 13(3): 329-337, 2017 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28521346