Detalhe da pesquisa
1.
Using Dynamic Oral Dosing of Rifapentine and Rifabutin to Simulate Exposure Profiles of Long-Acting Formulations in a Mouse Model of Tuberculosis Preventive Therapy.
Antimicrob Agents Chemother
; 67(7): e0048123, 2023 07 18.
Artigo
Inglês
| MEDLINE | ID: mdl-37338374
2.
Preserved Efficacy and Reduced Toxicity with Intermittent Linezolid Dosing in Combination with Bedaquiline and Pretomanid in a Murine Tuberculosis Model.
Antimicrob Agents Chemother
; 64(10)2020 09 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32690647
3.
Polymeric nanofiber coating with tunable combinatorial antibiotic delivery prevents biofilm-associated infection in vivo.
Proc Natl Acad Sci U S A
; 113(45): E6919-E6928, 2016 Nov 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27791154
4.
Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.
Proc Natl Acad Sci U S A
; 110(36): E3445-54, 2013 Sep 03.
Artigo
Inglês
| MEDLINE | ID: mdl-23946421
5.
Using dynamic oral dosing of rifapentine and rifabutin to simulate exposure profiles of long-acting formulations in a mouse model of tuberculosis preventive therapy.
bioRxiv
; 2023 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37090528
6.
Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.
J Med Chem
; 66(14): 9401-9417, 2023 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37439511
7.
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.
Nat Commun
; 13(1): 5992, 2022 10 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36220877
8.
Adjunct antibody administration with standard treatment reduces relapse rates in a murine tuberculosis model of necrotic granulomas.
PLoS One
; 13(5): e0197474, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29758082
9.
Noninvasive 11C-rifampin positron emission tomography reveals drug biodistribution in tuberculous meningitis.
Sci Transl Med
; 10(470)2018 12 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30518610
10.
Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models.
Cancer Chemother Pharmacol
; 59(5): 561-74, 2007 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-17160391
11.
The biodistribution of 5-[18F]fluoropyrazinamide in Mycobacterium tuberculosis-infected mice determined by positron emission tomography.
PLoS One
; 12(2): e0170871, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28151985
12.
A Systematic Approach for Developing Bacteria-Specific Imaging Tracers.
J Nucl Med
; 58(1): 144-150, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-27635025
13.
A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors.
Cancer Res
; 76(2): 480-90, 2016 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26744529
14.
Targeting the insulin-like growth factor axis for the development of novel therapeutics in oncology.
Cancer Res
; 72(1): 3-12, 2012 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22215692
15.
Therapeutic mechanism and efficacy of the antibody-drug conjugate BAY 79-4620 targeting human carbonic anhydrase 9.
Mol Cancer Ther
; 11(2): 340-9, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22147747
16.
Dual IGF-I/II-neutralizing antibody MEDI-573 potently inhibits IGF signaling and tumor growth.
Cancer Res
; 71(3): 1029-40, 2011 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21245093