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1.
Lung India ; 41(2): 151-167, 2024 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-38700413

RESUMO

ABSTRACT: Medical Thoracoscopy (MT) is commonly performed by respiratory physicians for diagnostic as well as therapeutic purposes. The aim of the study was to provide evidence-based information regarding all aspects of MT, both as a diagnostic tool and therapeutic aid for pulmonologists across India. The consensus-based guidelines were formulated based on a multistep process using a set of 31 questions. A systematic search of published randomized controlled clinical trials, open labelled studies, case reports and guidelines from electronic databases, like PubMed, EmBase and Cochrane, was performed. The modified grade system was used (1, 2, 3 or usual practice point) to classify the quality of available evidence. Then, a multitude of factors were taken into account, such as volume of evidence, applicability and practicality for implementation to the target population and then strength of recommendation was finalized. MT helps to improve diagnosis and patient management, with reduced risk of post procedure complications. Trainees should perform at least 20 medical thoracoscopy procedures. The diagnostic yield of both rigid and semirigid techniques is comparable. Sterile-graded talc is the ideal agent for chemical pleurodesis. The consensus statement will help pulmonologists to adopt best evidence-based practices during MT for diagnostic and therapeutic purposes.

2.
Proc (Bayl Univ Med Cent) ; 35(6): 854-855, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36304625

RESUMO

Small bowel diverticulum, though rare, can result in complications including diverticulitis, hemorrhage, intussusception, fistula, perforation, or bacterial overgrowth. Here, we present a case of gastrointestinal bleeding as a complication of jejunal diverticulum, resulting in hemorrhagic shock. The patient had a negative endoscopy and colonoscopy, prompting computed tomography angiogram, which identified one jejunal diverticulum with active contrast extravasation into the lumen of the small bowel. She underwent successful coil embolization, resulting in cessation of bleeding. This case demonstrates the difficult but successful identification of nonsteroidal antiinflammatory drug-induced jejunal diverticular bleeding in the acute emergent setting.

3.
ACG Case Rep J ; 4: e23, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28286789

RESUMO

Herpes simplex virus (HSV) hepatitis is a rare cause of acute liver failure (ALF). It carries a mortality rate of 80% if untreated, thus early identification and treatment are critical. Without high clinical suspicion, HSV hepatitis is difficult to diagnose. A 48-year-old Hispanic female presented with a 4-day history of abdominal pain and a vaginal cuff tear requiring laparoscopic repair. She subsequently developed postsurgical disseminated HSV, resulting in ALF. Acyclovir was initiated, but she was resistant to treatment. She was given additional foscarnet and responded without requiring a liver transplant.

4.
BMJ Case Rep ; 20172017 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-28137904

RESUMO

Methicillin-resistant Staphylococcus aureus (MRSA) necrotising fasciitis (NF) is rare and constitutes a medical and surgical emergency. We report a case of a 53-year-old man with type-2 diabetes mellitus and newly diagnosed HIV infection who presented with 1 week of progressively worsening bilateral sharp thigh pain. On presentation, he was febrile, tachycardic and had bilateral thigh erythema and mild tenderness without open wounds. He had leucocytosis, lactic acidosis and acute kidney injury. Urgent incision and drainage (I&D) was performed for suspected NF. Blood cultures and I&D were positive for MRSA. Biopsy of bilateral thighs showed NF. He was treated with wound washout and 6 weeks of intravenous antibiotics. After undergoing skin graft for wounds, he was discharged to physical rehabilitation. Here we report severe sepsis from bilateral thigh MRSA NF in a patient with newly diagnosed HIV.


Assuntos
Diabetes Mellitus Tipo 2/complicações , Fasciite Necrosante/complicações , Infecções por HIV/complicações , Sepse/complicações , Infecções Estafilocócicas/complicações , Administração Intravenosa , Antibacterianos/uso terapêutico , Terapia Antirretroviral de Alta Atividade , Drenagem , Fasciite Necrosante/diagnóstico , Fasciite Necrosante/patologia , Fasciite Necrosante/terapia , Infecções por HIV/tratamento farmacológico , Humanos , Hipertensão/complicações , Masculino , Staphylococcus aureus Resistente à Meticilina , Pessoa de Meia-Idade , Sepse/terapia , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/patologia , Infecções Estafilocócicas/terapia , Irrigação Terapêutica , Coxa da Perna
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