Detalhe da pesquisa
1.
Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination.
EMBO J
; 42(3): e111898, 2023 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36385258
2.
Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation.
EMBO J
; 37(23)2018 12 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30446597
3.
Allosteric mechanism for site-specific ubiquitination of FANCD2.
Nat Chem Biol
; 16(3): 291-301, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31873223
4.
Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA.
EMBO Rep
; 21(7): e50133, 2020 07 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32510829
5.
Ubc9 sumoylation controls SUMO chain formation and meiotic synapsis in Saccharomyces cerevisiae.
Mol Cell
; 50(5): 625-36, 2013 Jun 06.
Artigo
Inglês
| MEDLINE | ID: mdl-23644018
6.
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
EMBO J
; 34(20): 2506-21, 2015 Oct 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26254304
7.
The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL.
J Biol Chem
; 290(34): 20995-21006, 2015 Aug 21.
Artigo
Inglês
| MEDLINE | ID: mdl-26149689
8.
Specificity and disease in the ubiquitin system.
Biochem Soc Trans
; 44(1): 212-27, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26862208
9.
Autoregulation of Parkin activity through its ubiquitin-like domain.
EMBO J
; 30(14): 2853-67, 2011 Jun 21.
Artigo
Inglês
| MEDLINE | ID: mdl-21694720
10.
Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity.
J Cell Biol
; 223(1)2024 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38032389
11.
Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site.
Sci Adv
; 8(39): eabq6353, 2022 Sep 30.
Artigo
Inglês
| MEDLINE | ID: mdl-36170365
12.
Structural basis of FANCD2 deubiquitination by USP1-UAF1.
Nat Struct Mol Biol
; 28(4): 356-364, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33795880
13.
Modes of allosteric regulation of the ubiquitination machinery.
Curr Opin Struct Biol
; 62: 189-196, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32305021
14.
Enzymatic preparation of monoubiquitinated FANCD2 and FANCI proteins.
Methods Enzymol
; 618: 73-104, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30850063
15.
Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1.
Life Sci Alliance
; 1(5): e201800162, 2018 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-30456385
16.
DHX15 regulates CMTR1-dependent gene expression and cell proliferation.
Life Sci Alliance
; 1(3): e201800092, 2018 Jun 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30079402
17.
RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation.
Cell Rep
; 23(6): 1599-1611, 2018 05 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29742418
18.
Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements.
J Med Chem
; 60(19): 8183-8191, 2017 10 12.
Artigo
Inglês
| MEDLINE | ID: mdl-28933844
19.
Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening.
J Med Chem
; 60(9): 4093-4098, 2017 05 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28437106
20.
Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat Struct Mol Biol
; 24(5): 475-483, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-28414322