Detalhe da pesquisa
1.
Regulation of ferroptotic cancer cell death by GPX4.
Cell
; 156(1-2): 317-331, 2014 Jan 16.
Artigo
Inglês
| MEDLINE | ID: mdl-24439385
2.
An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.
Cell
; 154(5): 1151-1161, 2013 Aug 29.
Artigo
Inglês
| MEDLINE | ID: mdl-23993102
3.
Drinkable in situ-forming tough hydrogels for gastrointestinal therapeutics.
Nat Mater
; 2024 Feb 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38413810
4.
Transcriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFB1-TBXT Network.
Am J Pathol
; 193(5): 532-547, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36804377
5.
Synthesis of Potent Cytotoxic Epidithiodiketopiperazines Designed for Derivatization.
J Org Chem
; 85(7): 4648-4662, 2020 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32126173
6.
Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives.
J Am Chem Soc
; 141(36): 14411-14420, 2019 09 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31422662
7.
A High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production.
Biochemistry
; 57(19): 2814-2827, 2018 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29676157
8.
Correlating chemical sensitivity and basal gene expression reveals mechanism of action.
Nat Chem Biol
; 12(2): 109-16, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26656090
9.
Discovery of a Small-Molecule Probe for V-ATPase Function.
J Am Chem Soc
; 137(16): 5563-8, 2015 Apr 29.
Artigo
Inglês
| MEDLINE | ID: mdl-25860544
10.
Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity.
J Neurosci
; 33(8): 3582-7, 2013 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-23426685
11.
Compressed phenotypic screens for complex multicellular models and high-content assays.
bioRxiv
; 2023 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36747859
12.
Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
bioRxiv
; 2023 Feb 27.
Artigo
Inglês
| MEDLINE | ID: mdl-36909640
13.
Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
Cell Chem Biol
; 30(9): 1156-1168.e7, 2023 09 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37689063
14.
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding.
Nat Cell Biol
; 7(7): 665-74, 2005 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-15951807
15.
Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.
Cell Metab
; 34(4): 564-580.e8, 2022 04 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35385705
16.
Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery.
Science
; 377(6604): eabm5551, 2022 07 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35862544
17.
Computationally guided high-throughput design of self-assembling drug nanoparticles.
Nat Nanotechnol
; 16(6): 725-733, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33767382
18.
NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1.
Neuron
; 51(4): 431-40, 2006 Aug 17.
Artigo
Inglês
| MEDLINE | ID: mdl-16908409
19.
Identification and local delivery of vasodilators for the reduction of ureteral contractions.
Nat Biomed Eng
; 4(1): 28-39, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31792422
20.
Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors.
Cell Rep
; 28(9): 2331-2344.e8, 2019 08 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31461650