Detalhe da pesquisa
1.
Omicron-specific mRNA vaccine induced cross-protective immunity against ancestral SARS-CoV-2 infection with low neutralizing antibodies.
J Med Virol
; 95(1): e28370, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36458553
2.
Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone.
Bioorg Chem
; 128: 105905, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35710525
3.
BPR0C261, An Analogous of Microtubule Disrupting Agent D-24851 Enhances the Radiosensitivity of Human Non-Small Cell Lung Cancer Cells via p53-Dependent and p53-Independent Pathways.
Int J Mol Sci
; 23(22)2022 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36430560
4.
Protective Effect of CXCR4 Antagonist DBPR807 against Ischemia-Reperfusion Injury in a Rat and Porcine Model of Myocardial Infarction: Potential Adjunctive Therapy for Percutaneous Coronary Intervention.
Int J Mol Sci
; 23(19)2022 Oct 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36233031
5.
Discovery of M Protease Inhibitors Encoded by SARS-CoV-2.
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32669265
6.
Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from mice.
Pharmacol Res
; 161: 105183, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32896579
7.
CSC-3436 inhibits TWIST-induced epithelial-mesenchymal transition via the suppression of Twist/Bmi1/Akt pathway in head and neck squamous cell carcinoma.
J Cell Physiol
; 234(6): 9118-9129, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30341909
8.
Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular interactions within the N-terminus of NS4A.
J Gen Virol
; 100(3): 457-470, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30707666
9.
Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors.
Bioorg Chem
; 83: 520-525, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30469144
10.
BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor.
Cancer Sci
; 109(11): 3591-3601, 2018 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-30142229
11.
Correction to "Oral Delivery of Peptide Drugs Using Nanoparticles Self-Assembled by Poly(γ-glutamic acid) and a Chitosan Derivative Functionalized by Trimethylation".
Bioconjug Chem
; 33(4): 747, 2022 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35275486
12.
Targeting Tumor Associated Phosphatidylserine with New Zinc Dipicolylamine-Based Drug Conjugates.
Bioconjug Chem
; 28(7): 1878-1892, 2017 07 19.
Artigo
Inglês
| MEDLINE | ID: mdl-28581724
13.
1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine.
Anesthesiology
; 126(5): 952-966, 2017 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28212204
14.
N-Indolylglycosides bearing modifications at the glucose C6-position as sodium-dependent glucose co-transporter 2 inhibitors.
Bioorg Med Chem
; 24(10): 2242-50, 2016 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27075813
15.
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.
Proc Natl Acad Sci U S A
; 110(19): E1779-87, 2013 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23610398
16.
IL-1ß promotes malignant transformation and tumor aggressiveness in oral cancer.
J Cell Physiol
; 230(4): 875-84, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25204733
17.
Novel Nrf2/ARE activator, trans-Coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38α/MAPKAPK-2 and PK-N3 signaling pathway.
Chem Res Toxicol
; 28(9): 1681-92, 2015 Sep 21.
Artigo
Inglês
| MEDLINE | ID: mdl-26275128
18.
Discovery of a Long Half-Life AURKA Inhibitor to Treat MYC-Amplified Solid Tumors as a Monotherapy and in Combination with Everolimus.
Mol Cancer Ther
; 23(6): 766-779, 2024 Jun 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38592383
19.
In vivo imaging of brain infarct with the novel fluorescent probe PSVue 794 in a rat middle cerebral artery occlusion-reperfusion model.
Mol Imaging
; 12(1): 8-16, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23348787
20.
BPR0C305, an orally active microtubule-disrupting anticancer agent.
Anticancer Drugs
; 24(10): 1047-57, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24025560