Detalhe da pesquisa
1.
Structural basis for FGF hormone signalling.
Nature
; 618(7966): 862-870, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37286607
2.
C-terminal fragment of fibroblast growth factor 23 improves heart function in murine models of high intact fibroblast growth factor 23.
Am J Physiol Renal Physiol
; 326(4): F584-F599, 2024 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38299214
3.
Hypericin Alleviates Chronic Kidney Disease-induced Left Ventricular Hypertrophy by Regulation of FGF23-FGFR4 Signaling Pathway.
J Cardiovasc Pharmacol
; 83(6): 588-601, 2024 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38547517
4.
α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.
Nature
; 553(7689): 461-466, 2018 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-29342138
5.
A novel indazole derivative, compound Cyy-272, attenuates LPS-induced acute lung injury by inhibiting JNK phosphorylation.
Toxicol Appl Pharmacol
; 428: 115648, 2021 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34280409
6.
C-FGF23 peptide alleviates hypoferremia during acute inflammation.
Haematologica
; 106(2): 391-403, 2021 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32193252
7.
Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy.
Acta Pharmacol Sin
; 41(8): 1093-1101, 2020 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-32341464
8.
Myeloid differentiation protein 2-dependent mechanisms in retinal ischemia-reperfusion injury.
Toxicol Appl Pharmacol
; 317: 1-11, 2017 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28063877
9.
Inhibition of inflammation and oxidative stress by an imidazopyridine derivative X22 prevents heart injury from obesity.
J Cell Mol Med
; 20(8): 1427-42, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27019072
10.
Curcumin Analog L48H37 Prevents Lipopolysaccharide-Induced TLR4 Signaling Pathway Activation and Sepsis via Targeting MD2.
J Pharmacol Exp Ther
; 353(3): 539-50, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25862641
11.
A peptide derivative serves as a fibroblast growth factor 2 antagonist in human gastric cancer.
Tumour Biol
; 36(9): 7233-41, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-25894376
12.
Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents.
Bioorg Med Chem
; 22(24): 6953-60, 2014 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25456085
13.
Chalcone-derivative L6H21 attenuates the OVA-induced asthma by targeting MD2.
Eur J Med Res
; 29(1): 65, 2024 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38245791
14.
Compound SJ-12 attenuates streptozocin-induced diabetic cardiomyopathy by stabilizing SERCA2a.
Biochim Biophys Acta Mol Basis Dis
; 1870(5): 167140, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38548092
15.
3''-(2-Fluoro-benzyl-idene)-4'-(2-fluoro-phen-yl)-1'-methyl-dispiro-[acenaphthyl-ene-1,2'-pyrrolidine-3',1''-cyclo-penta-ne]-2,2''-dione.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 2): o249-50, 2013 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23424528
16.
Identification of linderalactone as a natural inhibitor of SHP2 to ameliorate CCl4-induced liver fibrosis.
Front Pharmacol
; 14: 1098463, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36843936
17.
Determine the enzymatic kinetic characteristics of CYP3A4 variants utilizing artemether-lumefantrine.
Food Chem Toxicol
; 181: 114065, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37769895
18.
Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen.
J Med Chem
; 66(10): 6938-6958, 2023 05 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37130331
19.
Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis.
Int Immunopharmacol
; 120: 110292, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-37182452
20.
Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis.
Eur J Med Chem
; 249: 115144, 2023 Mar 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36708679