Detalhe da pesquisa
1.
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.
Nature
; 593(7859): 429-434, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34012082
2.
Distinct functions and temporal regulation of methylated histone H3 during early embryogenesis.
Development
; 146(19)2019 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31540912
3.
Cracking the cytotoxicity code: apoptotic induction of 10-acetylirciformonin B is mediated through ROS generation and mitochondrial dysfunction.
Mar Drugs
; 12(5): 3072-90, 2014 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24857964
4.
10-acetylirciformonin B, a sponge furanoterpenoid, induces DNA damage and apoptosis in leukemia cells.
Molecules
; 17(10): 11839-48, 2012 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-23047484
5.
Molecular characterization of precise in vivo targeted gene integration in human cells using AAVHSC15.
PLoS One
; 15(5): e0233373, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32453743
6.
Regulated nuclear accumulation of a histone methyltransferase times the onset of heterochromatin formation in C. elegans embryos.
Sci Adv
; 4(8): eaat6224, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30140741
7.
Resistance enhancement of transgenic tomato to bacterial pathogens by the heterologous expression of sweet pepper ferredoxin-I protein.
Phytopathology
; 97(8): 900-6, 2007 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-18943629
8.
Cloning and characterization of a plant defensin VaD1 from azuki bean.
J Agric Food Chem
; 53(4): 982-8, 2005 Feb 23.
Artigo
Inglês
| MEDLINE | ID: mdl-15713009
9.
Lack of type VI adenylyl cyclase (AC6) leads to abnormal sympathetic tone in neonatal mice.
Exp Neurol
; 248: 10-5, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23726959
10.
Repression of meiotic genes by antisense transcription and by Fkh2 transcription factor in Schizosaccharomyces pombe.
PLoS One
; 7(1): e29917, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22238674
11.
A conserved regulatory role for antisense RNA in meiotic gene expression in yeast.
Curr Opin Microbiol
; 14(6): 655-9, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21963111
12.
The fission yeast RNA binding protein Mmi1 regulates meiotic genes by controlling intron specific splicing and polyadenylation coupled RNA turnover.
PLoS One
; 6(10): e26804, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-22046364
13.
A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species.
Free Radic Biol Med
; 50(9): 1151-62, 2011 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21256211
14.
Comparative functional genomics of the fission yeasts.
Science
; 332(6032): 930-6, 2011 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-21511999
15.
A complex gene regulatory mechanism that operates at the nexus of multiple RNA processing decisions.
Nat Struct Mol Biol
; 16(3): 255-64, 2009 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19198588
16.
Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells.
Cancer Lett
; 286(2): 161-71, 2009 Dec 28.
Artigo
Inglês
| MEDLINE | ID: mdl-19589639