Detalhe da pesquisa
1.
Aberrant splicing of mutant huntingtin in Huntington's disease knock-in pigs.
Neurobiol Dis
; 187: 106291, 2023 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37716514
2.
Lack of association of somatic CAG repeat expansion with striatal neurodegeneration in HD knock-in animal models.
Hum Mol Genet
; 30(16): 1497-1508, 2021 07 28.
Artigo
Inglês
| MEDLINE | ID: mdl-33949657
3.
Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains.
Cell Mol Life Sci
; 79(11): 554, 2022 Oct 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36251080
4.
HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice.
Cell Death Dis
; 15(5): 337, 2024 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38744826
5.
TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington's disease.
Sci Adv
; 10(20): eadl2036, 2024 May 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38758800
6.
Loss of TDP-43 promotes somatic CAG repeat expansion in Huntington's disease knock-in mice.
Prog Neurobiol
; 227: 102484, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37315918
7.
Mutant HTT does not affect glial development but impairs myelination in the early disease stage.
Front Neurosci
; 17: 1238306, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37539389
8.
Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice.
Front Cell Neurosci
; 16: 1021592, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36439204
9.
SQSTM1-mediated clearance of cytoplasmic mutant TARDBP/TDP-43 in the monkey brain.
Autophagy
; 18(8): 1955-1968, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34936539
10.
Cytoplasmic TDP-43 impairs the activity of the ubiquitin-proteasome system.
Exp Neurol
; 345: 113833, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34363810
11.
Mutant Ahi1 Affects Retinal Axon Projection in Zebrafish via Toxic Gain of Function.
Front Cell Neurosci
; 13: 81, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30949029