Point diffraction interferometer based on a silicon nitride waveguide spherical wave source.

A point diffraction interferometer based on silicon nitride waveguide (WG-PDI), adopting a silicon nitride waveguide spherical wave source (WG-SWS) with Si substrate and SiO2 cladding, is proposed for spherical surface testing. The WG-SWS is used to overcome the drawbacks of the existing spherical wave sources, which can generate high accuracy and high numerical aperture spherical reference wave. In this paper, the theory of the WG-PDI is described, and the possible errors introduced by the device are analyzed. In addition, the lateral deviation between the curvature center of the test wave and the curvature center of the reference wave cannot be eliminated in the reflected configuration of the pinhole diffraction interferometer. After analyzing the influence of the systematic error introduced by the lateral deviation, the semi-reflective film was coated on the output facet of the waveguide spherical wave source to realize point diffraction interference without lateral deviation. Finally, the surface error of a spherical surface was measured by WG-PDI. The experimental results agree well with those measured by the ZYGO interferometer.

Three new cassane-type diterpenoids from Caesalpinia sinensis.

Three new cassane-type diterpenoids, namely, (4S)-6ß,12α,19-trihydroxy-cass-13(15)-en-16,12-olide (1), cass-13(15)-en-​16,12-olide (2), and 12α-hydroxy-cass-13(15)-en-16,12-olide (3), were isolated from the seeds of Caesalpinia sinensis. The structures of 1-3 were established by extensive spectroscopic analysis, and their absolute configurations were assigned by electronic circular dichroism (ECD) calculations. The inhibitory activities against PTP1B of the isolated compounds were evaluated. The results showed that compound 2 possessed PTP1B inhibitory activity with an IC50 value of 217.45 ± 36.4 µM.

Reference wave source based on silicon nitride waveguide in point diffraction interferometer.

Reference wave source (RWS) is the key component of the point diffraction interferometer, which determines the quality of the reference wave. The silicon nitride waveguide RWS is proposed to efficiently overcome the drawbacks of the existing RWSs, aimed at providing a spherical reference wave with high numerical aperture (NA) and high accuracy. The waveguide RWS consists of the straight waveguide, the bend waveguide, and the Y-branch edge coupler. The straight waveguide determines the accuracy and the NA of the reference wave, whereas the latter two determine the light transmittance of the RWS. Simulation results show that the peak-to-valley (PV) and the rms of the deviation from an ideal spherical wave are 2.86×10-4λ (λ=532nm) and 4.83×10-5λ, respectively, and the maximum light transmittance could reach 24%. Experiment results show that the NA of the reference wave reaches up to 0.58, its spot has a good circular symmetry, and its intensity has Gaussian distribution. Although the light transmittance is only 0.2%, it is expected to improve with the development of experimental conditions and waveguide fabrication technology.

Characterization of the pinhole diffraction based on the waveguide effect in a point diffraction interferometer.

The nearly ideal spherical wavefront generated by pinhole diffraction is the key factor determining the achievable accuracy in point diffraction interferometers (PDIs), as it is employed as the reference wavefront. A comprehensive characterization of the diffraction of a pinhole at the operating-wavelength scale that is normally adopted in PDI is given. The incident light is coupled into the pinhole, which functions as a cylindrical waveguide, and is diffracted in the end. The field in the pinhole is analyzed based on mode theory and the diffraction wave in the far field is derived from the field equivalence principle. The diffraction wave is characterized by the light transmittance, the polarization, and the wavefront aberration, which are all determined by the properties of the mode in the pinhole. The diameter of the pinhole should not be smaller than 0.6λ to make the transmittance sufficient. With a linearly polarized incident light, the diffraction wave is elliptically polarized, and the wavefront aberration is dominated by the astigmatic component. The method explicitly reveals the physical mechanism of pinhole diffraction. The analytic solutions are fast to compute, easy to analyze, and intuitively show the diffractive properties of the pinhole. The conclusions are significant for insight into the nature of pinhole diffraction and provide theoretical reference for analysis of numerical results and the design of PDI systems.

Comprehensive design and calibration of an even aspheric quarter-wave plate for polarization point diffraction interferometry.

A polarization point diffraction interferometry (PPDI) system, adopting a specially designed even aspheric quarter-wave plate (EAQWP) in the test path, is proposed for low-reflectivity and high-numerical-aperture spherical surface testing. In terms of the low-reflectivity mirror measurement, the obtained poor fringes contrast, which can significantly affect the measurement accuracy, can be improved by the polarization characteristic of the EAQWP. Simultaneously, the wavefront distortion, especially larger in high-numerical apperture (NA) measurement, can be greatly reduced attributable to the even aspheric surface design instead of the plane. In addition, the pose error introduced by EAQWP is demonstrated in detail, and a difference restoration model is built to calibrate it. Consequently, the location of the EAQWP is fixed in the test path after calibrating the pose error, having no need to be adjusted with the change of the spherical mirror under test, which facilitates the system alignment in practical optical shop testing. Ultimately, the surface error of a spherical mirror with a low-reflectivity of 0.04 and a high NA of 0.5 is measured with PPDI. The experimental results are validated to be in good agreement with that of a ZYGO interferometer.

Two new norcassane-type diterpenoids from Mezonevron sinense Hemsl.

Two new norcassane-type diterpenoids, named 6ß-hydroxy-bisnorcass-13-en-12-one (1) and 6ß-hydroxy-bisnorcassan-12-one (2), were isolated from the seeds of Mezonevron sinense Hemsl. The structures of compounds 1-2 were determined by extensive spectroscopic analysis. Two compounds exhibited immunosuppressive activity with the IC50 values of 19.35 ± 0.87 µM and 18.69 ± 0.88 µM in the ConA induced T cell model and 65.04 ± 0.83 µM and 48.06 ± 0.76 µM in LPS induced B cell model, respectively.

Synthesis, thermal behaviors, and energetic properties of asymmetrically substituted tetrazine-based energetic materials.

1,2,4,5-tetrazine ring is a common structure for the construction of energy-containing compounds, and its high nitrogen content and large conjugation effect give it the advantage of a good balance between energy and mechanical stability as a high-nitrogen energy-containing material. However, most of the reported works about tetrazine energetic materials (EMs) are symmetrically substituted tetrazines due to their easy accessibility. A small number of reports show that asymmetrically substituted tetrazines also have good properties, such as high density and generation of enthalpy and energy. Herein, two asymmetrically substituted tetrazines and their five energetic salts were prepared and fully characterized by IR spectroscopy, NMR spectra, elemental analysis, and differential scanning calorimetry (DSC). The structure of the two compounds was further confirmed by single-crystal X-ray diffraction studies. The thermal behaviors and thermodynamic parameters were determined and calculated. In addition, the energetic properties and impact sensitivities of all the compounds were obtained to assess their application potential. The results show that compounds 2-4 and 7-9 show higher detonation velocities than TNT, and the hydrazinium salt 9 possesses the best detonation properties (D = 8,232 m s-1 and p = 23.6 GPa). Except for 4 and 3, all the other compounds are insensitive, which may be applied as insensitive explosives. Noncovalent interaction analysis was further carried out, and the result shows that the strong and high proportion of hydrogen bonds may contribute to the low-impact sensitivity.

Chronic REM-sleep deprivation induced laryngopharyngeal reflux in rats: A preliminary study.

OBJECTIVE: The aim of this study was to investigate the relationship of chronic REM-sleep deprivation with laryngopharyngeal reflux (LPR) and its mechanism. METHODS: Forty healthy male SD rats (body weight 250-280 g) were randomly divided into four groups. The first three ones were test group, which underwent REM-sleep deprivation with different duration of time by modified multiplatform water surface method. The last group was the control one having normal sleep. All the animals were performed Dx-pH monitoring when finishing sleep deprivation, and sacrificed to study the gastric residual rate (GRR) and small intestine peristalsis (SPR) rate by charcoal meal method. RESULTS: At prone position, the reflux incidence in the test groups fairly increased with the duration of sleep deprivation (p<0.05). The total number of reflux episodes at prone position in the test group rats with 3 months duration of sleep deprivation was significantly increased compared with that in the control ones (p<0.05). GRR in rats experiencing sleep deficiency for different duration all reduced significantly when compared to the control group (p<0.05). GRR and SPR presented continuous decline tendency with the duration of sleep deprivation (p>0.05). CONCLUSIONS: It is suggested that chronic sleep deficiency could cause LPR in rats, which might result from the uncoordinated digestive tract motility caused by dysfunction of central nervous system after chronic REM-sleep deprivation. Our results implied that chronic REM-sleep deprivation might be one of the causes of LPR. Addressing sleep problems might help to decrease the prevalence of LPR and enhance its treatment efficacy.

Narrow-wide row planting pattern improves the light environment and seed yields of intercrop species in relay intercropping system.

Different planting patterns affect the light interception of intercrops under intercropping conditions. Here we revealed that narrow-wide-row relay-intercropping improves the light interception across maize leaves in wide rows (60cm) and narrow rows (40cm), accelerated the biomass production of intercrop-species and compensated the slight maize yield loss by considerably increasing the soybean yield. In a two-year experiment, maize was planted with soybean in different planting patterns (1M1S, 50:50cm and 2M2S, 40:60cm) of relay-intercropping, both planting patterns were compared with sole cropping of maize (M) and soybean (S). As compared to M and 1M1S, 2M2S increased the total light interception of maize leaves in wide rows (WR) by 27% and 23%, 20% and 10%, 16% and 9% which in turn significantly enhanced the photosynthetic rate of WR maize leaves by 7% and 5%, 12% and 9%, and 19% and 4%, at tasseling, grain-filling and maturity stage of maize, respectively. Similarly, the light transmittance at soybean canopy increased by 218%, 160% and 172% at V2, V5 and R1 stage in 2M2S compared with 1M1S. The improved light environment at soybean canopy in 2M2S considerably enhanced the mean biomass accumulation, and allocation to stem and leaves of soybean by 168%, and 131% and 207%, respectively, while it decreased the mean biomass accumulation, and distribution to stem, leaves and seed of maize by 4%, and 4%, 6% and 5%, respectively than 1M1S. Compared to 1M1S, 2M2S also increased the CR values of soybean (by 157%) but decreased the CR values of maize (by 61%). Overall, under 2M2S, relay-cropped maize and soybean produced 94% and 69% of the sole cropping yield, and the 2M2S achieved LER of 1.7 with net income of 1387.7 US $ ha-1 in 2016 and 1434.4 US $ ha-1 in 2017. Our findings implied that selection of optimum planting pattern (2M2S) may increase the light interception and influence the light distribution between maize and soybean rows under relay-intercropping conditions which will significantly increase the intercrops productivity. Therefore, more attention should be paid to the light environment when considering the sustainability of maize-soybean relay-intercropping via appropriate planting pattern selection.

The Influence of Light Intensity and Leaf Movement on Photosynthesis Characteristics and Carbon Balance of Soybean.

In intercropping systems shading conditions significantly impair the seed yield and quality of soybean, and rarely someone investigated the minimum amount of light requirement for soybean growth and development. Therefore, it is an urgent need to determine the threshold light intensity to ensure sustainable soybean production under these systems. An integrated approach combining morphology, physiology, biochemistry and genetic analysis was undertaken to study the light intensity effects on soybean growth and development. A pot experiment was set up in a growth chamber under increasing light intensity treatments of 100 (L100), 200 (L200), 300 (L300), 400 (L400), and 500 (L500) µmol m-2 s-1. Compared with L100, plant height, hypocotyl length, and abaxial leaf petiole angle were decreased, biomass, root:shoot ratio, and stem diameter were increased, extremum was almost observed in L400 and L500. Leaf petiole movement and leaf hyponasty in each treatment has presented a tendency to decrease the leaf angle from L500 to L100. In addition, the cytochrome content (Chl a, Chl b, Car), net photosynthetic rate, chlorophyll fluorescence values of F v/F m, F v ' / F m ' , ETR, ΦPSII, and qP were increased as the light intensity increased, and higher values were noted under L400. Leaf microstructure and chloroplast ultrastructure positively improved with increasing light intensity, and leaf-thickness, palisade, and spongy tissues-thickness were increased by 105, 90, and 370%, under L500 than L100. Moreover, the cross-sectional area of chloroplast (C) outer membrane and starch grains (S), and sectional area ratio (S:C) was highest under L400 and L500, respectively. Compared to L100, the content of starch granules increased by 35.5, 122.0, 157.6, and 145.5%, respectively in L400. The same trends were observed in the enzyme activity of sucrose-synthase, sucrose phosphate synthase, starch synthase, rubisco, phosphoenol pyruvate carboxykinase, and phosphoenol pyruvate phosphatase. Furthermore, sucrose synthesis-related genes were also up-regulated by increasing light intensity, and the highest seed yield and yield related parameters were recorded in the L400. Overall, these results suggested that 400 and 500 µmol m-2 s-1 is the optimum light intensity which positively changed the leaf orientation and adjusts leaf angle to perpendicular to coming light, consequently, soybean plants grow well under prevailing conditions.