Detalhe da pesquisa
1.
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.
Nature
; 593(7859): 429-434, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34012082
2.
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.
Nature
; 518(7537): 107-10, 2015 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25409146
3.
Exercise and weight loss interventions and miRNA expression in women with breast cancer.
Breast Cancer Res Treat
; 170(1): 55-67, 2018 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-29511965
4.
Arginase I mRNA therapy - a novel approach to rescue arginase 1 enzyme deficiency.
RNA Biol
; 15(7): 914-922, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29923457
5.
Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA.
RNA Biol
; 15(6): 756-762, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29578372
6.
Enhancing potency of siRNA targeting fusion genes by optimization outside of target sequence.
Proc Natl Acad Sci U S A
; 112(48): E6597-605, 2015 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26627251
7.
Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A.
Proc Natl Acad Sci U S A
; 111(30): E3062-71, 2014 Jul 29.
Artigo
Inglês
| MEDLINE | ID: mdl-25024194
8.
miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction.
J Neurosci
; 35(26): 9764-81, 2015 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26134658
9.
Sustained delivery of proangiogenic microRNA-132 by nanoparticle transfection improves endothelial cell transplantation.
FASEB J
; 28(2): 908-22, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24221087
10.
Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma.
Proc Natl Acad Sci U S A
; 109(26): E1695-704, 2012 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-22685206
11.
Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer.
Nanomedicine
; 9(8): 1124-34, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23764660
12.
Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery.
Nat Mater
; 11(1): 82-90, 2011 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-22138789
13.
Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing.
Mol Pharm
; 9(5): 1481-8, 2012 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-22482958
14.
Improved CRISPR genome editing using small highly active and specific engineered RNA-guided nucleases.
Nat Commun
; 12(1): 4219, 2021 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34244505
15.
miR-155 drives oncogenesis by promoting and cooperating with mutations in the c-Kit oncogene.
Oncogene
; 38(12): 2151-2161, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30459357
16.
A "top-down" approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery.
Biomaterials
; 176: 122-130, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29879653
17.
Leveraging Rational Protein Engineering to Improve mRNA Therapeutics.
Nucleic Acid Ther
; 28(2): 74-85, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29437538
18.
Addendum to: Improved CRISPR genome editing using small highly active and specific engineered RNA-guided nucleases.
Nat Commun
; 14(1): 3503, 2023 06 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37311765
19.
miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer.
Cancer Res
; 76(4): 927-39, 2016 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26676753
20.
In vivo correction of anaemia in ß-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery.
Nat Commun
; 7: 13304, 2016 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-27782131