Detalhe da pesquisa
1.
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
Nat Chem Biol
; 17(9): 954-963, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33972797
2.
Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Mol Cancer
; 21(1): 126, 2022 06 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35689207
3.
Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity.
Blood
; 136(10): 1155-1160, 2020 09 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32573723
4.
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-ß-OTX2-SNAIL via PTEN inhibition.
Brain
; 141(5): 1300-1319, 2018 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29490009
5.
Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors.
Proc Natl Acad Sci U S A
; 113(48): 13726-13731, 2016 11 29.
Artigo
Inglês
| MEDLINE | ID: mdl-27837025
6.
Pleiotropic role for MYCN in medulloblastoma.
Genes Dev
; 24(10): 1059-72, 2010 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20478998
7.
From class waivers to precision medicine in paediatric oncology.
Lancet Oncol
; 18(7): e394-e404, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28677575
8.
Pre-clinical imaging of transgenic mouse models of neuroblastoma using a dedicated 3-element solenoid coil on a clinical 3T platform.
Br J Cancer
; 117(6): 791-800, 2017 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28787429
9.
Better translation via collaboration: The MRC National Mouse Genetics Network.
Cell Genom
; 4(2): 100483, 2024 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38359786
10.
Precision Medicine for Childhood Cancer: Current Limitations and Future Perspectives.
JCO Precis Oncol
; 8: e2300117, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38207228
11.
A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations.
Nat Commun
; 15(1): 3745, 2024 May 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38702304
12.
Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy.
Cancer Cell
; 42(2): 283-300.e8, 2024 02 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38181797
13.
Bevacizumab, Irinotecan, or Topotecan Added to Temozolomide for Children With Relapsed and Refractory Neuroblastoma: Results of the ITCC-SIOPEN BEACON-Neuroblastoma Trial.
J Clin Oncol
; 42(10): 1135-1145, 2024 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38190578
14.
Evaluation of clinically translatable MR imaging biomarkers of therapeutic response in the TH-MYCN transgenic mouse model of neuroblastoma.
Radiology
; 266(1): 130-40, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23169794
15.
Genetically engineered murine models--contribution to our understanding of the genetics, molecular pathology and therapeutic targeting of neuroblastoma.
Semin Cancer Biol
; 21(4): 245-55, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21958944
16.
Palbociclib releases the latent differentiation capacity of neuroblastoma cells.
Dev Cell
; 58(19): 1967-1982.e8, 2023 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37734383
17.
Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models.
Clin Cancer Res
; 29(7): 1317-1331, 2023 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36602782
18.
Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results.
Nat Med
; 29(5): 1092-1102, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37012551
19.
Liquid biopsy for children with central nervous system tumours: Clinical integration and technical considerations.
Front Pediatr
; 10: 957944, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36467471
20.
The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme.
Cancer Gene Ther
; 29(7): 940-950, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34522028