Detalhe da pesquisa
1.
Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET.
J Biol Chem
; 296: 100641, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33839159
2.
Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor.
J Pharmacol Exp Ther
; 372(3): 339-353, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31818916
3.
The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL).
Bioorg Med Chem Lett
; 30(12): 127198, 2020 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32334914
4.
The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors.
Bioorg Med Chem Lett
; 30(14): 127243, 2020 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32527545
5.
Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity.
J Lipid Res
; 56(6): 1153-71, 2015 06.
Artigo
Inglês
| MEDLINE | ID: mdl-25842377
6.
Erratum: Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity.
J Lipid Res
; 60(3): 717, 2019 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-30824679
7.
Amivantamab (JNJ-61186372), an Fc Enhanced EGFR/cMet Bispecific Antibody, Induces Receptor Downmodulation and Antitumor Activity by Monocyte/Macrophage Trogocytosis.
Mol Cancer Ther
; 19(10): 2044-2056, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32747419
8.
Triazinediones as prokineticin 1 receptor antagonists. Part 1: SAR, synthesis and biological evaluation.
Bioorg Med Chem Lett
; 19(10): 2661-3, 2009 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19375913
9.
A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors.
Cancer Res
; 76(13): 3942-53, 2016 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27216193
10.
Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range.
Pharmacol Biochem Behav
; 96(2): 130-5, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-20438745
11.
Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.
Toxicol Sci
; 117(2): 493-504, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20616206