Detalhe da pesquisa
1.
Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as a therapeutic strategy in CLL.
Blood
; 141(26): 3166-3183, 2023 06 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37084385
2.
Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3.
Mol Pharmacol
; 105(4): 301-312, 2024 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38346795
3.
G protein-receptor kinases 5/6 are the key regulators of G protein-coupled receptor 35-arrestin interactions.
J Biol Chem
; 299(10): 105218, 2023 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-37660910
4.
Systematic assessment of chemokine ligand bias at the human chemokine receptor CXCR2 indicates G protein bias over ß-arrestin recruitment and receptor internalization.
Cell Commun Signal
; 22(1): 43, 2024 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38233929
5.
Cannabidiol negatively modulates adenosine A2A receptor functioning in living cells.
Acta Neuropsychiatr
; : 1-5, 2023 Aug 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37605951
6.
CXCR4-Binding Positron Emission Tomography Tracers Link Monocyte Recruitment and Endothelial Injury in Murine Atherosclerosis.
Arterioscler Thromb Vasc Biol
; 41(2): 822-836, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33327748
7.
Active Components from Cassia abbreviata Prevent HIV-1 Entry by Distinct Mechanisms of Action.
Int J Mol Sci
; 22(9)2021 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34068829
8.
Structural Features of an Extended C-Terminal Tail Modulate the Function of the Chemokine CCL21.
Biochemistry
; 59(13): 1338-1350, 2020 04 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32182428
9.
Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes ß-Arrestin 2 Recruitment.
Mol Pharmacol
; 91(6): 595-608, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28314853
10.
Profiling the Extended Cleavage Specificity of the House Dust Mite Protease Allergens Der p 1, Der p 3 and Der p 6 for the Prediction of New Cell Surface Protein Substrates.
Int J Mol Sci
; 18(7)2017 Jun 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28654001
11.
The Lys-Asp-Tyr Triad within the Mite Allergen Der p 1 Propeptide Is a Critical Structural Element for the pH-Dependent Initiation of the Protease Maturation.
Int J Mol Sci
; 18(5)2017 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-28531096
12.
Neutralising properties of peptides derived from CXCR4 extracellular loops towards CXCL12 binding and HIV-1 infection.
Biochim Biophys Acta
; 1843(5): 1031-41, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24480462
13.
Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus.
Biochim Biophys Acta
; 1840(3): 1117-24, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24291687
14.
Allosteric inhibition of VIM metallo-ß-lactamases by a camelid nanobody.
Biochem J
; 450(3): 477-86, 2013 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23289540
15.
Emerging roles of the protease allergen Der p 1 in house dust mite-induced airway inflammation.
J Allergy Clin Immunol
; 142(2): 398-400, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29906529
16.
Systematic Assessment of Human CCR7 Signalling Using NanoBRET Biosensors Points towards the Importance of the Cellular Context.
Biosensors (Basel)
; 14(3)2024 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38534251
17.
New pairings and deorphanization among the atypical chemokine receptor family - physiological and clinical relevance.
Front Immunol
; 14: 1133394, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37153591
18.
Nanoluciferase-based complementation assays to monitor activation, modulation and signaling of receptor tyrosine kinases (RTKs).
Methods Enzymol
; 682: 1-16, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36948698
19.
GPR182 is a broadly scavenging atypical chemokine receptor influencing T-independent immunity.
Front Immunol
; 14: 1242531, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37554323
20.
Reduced G protein signaling despite impaired internalization and ß-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.
JCI Insight
; 8(5)2023 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36883568