Detalhe da pesquisa
1.
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.
Nature
; 586(7830): 560-566, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32854108
2.
Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.
Nature
; 590(7844): E22, 2021 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-33469219
3.
Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors.
Bioorg Med Chem Lett
; 20(14): 4060-4, 2010 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20541404
4.
A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures.
bioRxiv
; 2020 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32511406
5.
A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties.
Bioorg Med Chem Lett
; 18(21): 5763-5, 2008 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18842409
6.
Modifications of the isonipecotic acid fragment of SNS-032: analogs with improved permeability and lower efflux ratio.
Bioorg Med Chem Lett
; 18(23): 6236-9, 2008 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18926699
7.
Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.
Bioorg Med Chem Lett
; 18(20): 5648-52, 2008 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18793847
8.
In situ assembly of enzyme inhibitors using extended tethering.
Nat Biotechnol
; 21(3): 308-14, 2003 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-12563278
9.
Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design.
J Med Chem
; 45(23): 5005-22, 2002 Nov 07.
Artigo
Inglês
| MEDLINE | ID: mdl-12408711
10.
Synthesis of Alkoxylamines by Alkoxide Amination with 3,3'-Di-tert-butyloxaziridine.
J Org Chem
; 64(18): 6528-6529, 1999 Sep 03.
Artigo
Inglês
| MEDLINE | ID: mdl-11674653
11.
Small-molecule inhibition of TNF-alpha.
Science
; 310(5750): 1022-5, 2005 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-16284179
12.
Identification of potent and novel small-molecule inhibitors of caspase-3.
Bioorg Med Chem Lett
; 13(21): 3651-5, 2003 Nov 03.
Artigo
Inglês
| MEDLINE | ID: mdl-14552750