Pesquisa | Secretaria de Estado da Saúde

1.

Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.

Pan, Liqiang; Fu, Tian-Min; Zhao, Wenbin; Zhao, Linlin; Chen, Wen; Qiu, Chixiao; Liu, Wenhui; Liu, Zhijun; Piai, Alessandro; Fu, Qingshan; Chen, Shuqing; Wu, Hao; Chou, James J.

Cell ; 176(6): 1477-1489.e14, 2019 03 07.

Artigo Inglês | MEDLINE | ID: mdl-30827683

2.

Molecular basis for interaction of let-7 microRNAs with Lin28.

Nam, Yunsun; Chen, Casandra; Gregory, Richard I; Chou, James J; Sliz, Piotr.

Cell ; 147(5): 1080-91, 2011 Nov 23.

Artigo Inglês | MEDLINE | ID: mdl-22078496

3.

An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrialâ£membrane.

Lv, Fujiao; Qi, Fei; Zhang, Zhi; Wen, Maorong; Kale, Justin; Piai, Alessandro; Du, Lingyu; Wang, Shuqing; Zhou, Liujuan; Yang, Yaqing; Wu, Bin; Liu, Zhijun; Del Rosario, Juan; Pogmore, Justin; Chou, James J; Andrews, David W; Lin, Jialing; OuYang, Bo.

EMBO J ; 40(14): e106438, 2021 07 15.

Artigo Inglês | MEDLINE | ID: mdl-34101209

4.

Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.

Fu, Qingshan; Fu, Tian-Min; Cruz, Anthony C; Sengupta, Prabuddha; Thomas, Stacy K; Wang, Shuqing; Siegel, Richard M; Wu, Hao; Chou, James J.

Mol Cell ; 61(4): 602-613, 2016 Feb 18.

Artigo Inglês | MEDLINE | ID: mdl-26853147

5.

Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif.

Xu, Chenqi; Gagnon, Etienne; Call, Matthew E; Schnell, Jason R; Schwieters, Charles D; Carman, Christopher V; Chou, James J; Wucherpfennig, Kai W.

Cell ; 135(4): 702-13, 2008 Nov 14.

Artigo Inglês | MEDLINE | ID: mdl-19013279

6.

Self-Assembled L-DNA Linkers for Rapid Construction of Multi-Specific Antibody-Drug Conjugates Library.

Zhou, Liujuan; Yang, Fan; Bai, Zhaoshuai; Zhou, Xiaohui; Zhang, Zhihai; Li, Zhihang; Gong, Junyuan; Yu, Junqi; Pan, Liqiang; Cao, Chan; Chou, James J.

Angew Chem Int Ed Engl ; 62(27): e202302805, 2023 07 03.

Artigo Inglês | MEDLINE | ID: mdl-36961368

7.

Structure of the Streptococcus pyogenes NAD⁺ Glycohydrolase Translocation Domain and Its Essential Role in Toxin Binding to Oropharyngeal Keratinocytes.

Velarde, Jorge J; Piai, Alessandro; Lichtenstein, Ian J; Lynskey, Nicola N; Chou, James J; Wessels, Michael R.

J Bacteriol ; 204(1): e0036621, 2022 01 18.

Artigo Inglês | MEDLINE | ID: mdl-34694903

8.

The structural basis for intramembrane assembly of an activating immunoreceptor complex.

Call, Matthew E; Wucherpfennig, Kai W; Chou, James J.

Nat Immunol ; 11(11): 1023-9, 2010 Nov.

Artigo Inglês | MEDLINE | ID: mdl-20890284

9.

HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes.

Xiao, Tianshu; Frey, Gary; Fu, Qingshan; Lavine, Christy L; Scott, David A; Seaman, Michael S; Chou, James J; Chen, Bing.

Nat Chem Biol ; 16(5): 529-537, 2020 05.

Artigo Inglês | MEDLINE | ID: mdl-32152540

10.

Architecture of the mitochondrial calcium uniporter.

Oxenoid, Kirill; Dong, Ying; Cao, Chan; Cui, Tanxing; Sancak, Yasemin; Markhard, Andrew L; Grabarek, Zenon; Kong, Liangliang; Liu, Zhijun; Ouyang, Bo; Cong, Yao; Mootha, Vamsi K; Chou, James J.

Nature ; 533(7602): 269-73, 2016 05 12.

Artigo Inglês | MEDLINE | ID: mdl-27135929

11.

A Trimeric Hydrophobic Zipper Mediates the Intramembrane Assembly of SARS-CoV-2 Spike.

Fu, Qingshan; Chou, James J.

J Am Chem Soc ; 143(23): 8543-8546, 2021 06 16.

Artigo Inglês | MEDLINE | ID: mdl-34086443

12.

NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology.

Piai, Alessandro; Fu, Qingshan; Sharp, Amanda K; Bighi, Beatrice; Brown, Anne M; Chou, James J.

J Am Chem Soc ; 143(17): 6609-6615, 2021 05 05.

Artigo Inglês | MEDLINE | ID: mdl-33882664

13.

Structure of the membrane proximal external region of HIV-1 envelope glycoprotein.

Fu, Qingshan; Shaik, Md Munan; Cai, Yongfei; Ghantous, Fadi; Piai, Alessandro; Peng, Hanqin; Rits-Volloch, Sophia; Liu, Zhijun; Harrison, Stephen C; Seaman, Michael S; Chen, Bing; Chou, James J.

Proc Natl Acad Sci U S A ; 115(38): E8892-E8899, 2018 09 18.

Artigo Inglês | MEDLINE | ID: mdl-30185554

14.

Inhibitor Development against p7 Channel in Hepatitis C Virus.

Wei, Shukun; Hu, Xiaoyou; Du, Lingyu; Zhao, Linlin; Xue, Hongjuan; Liu, Chaolun; Chou, James J; Zhong, Jin; Tong, Yimin; Wang, Shuqing; OuYang, Bo.

Molecules ; 26(5)2021 Mar 03.

Artigo Inglês | MEDLINE | ID: mdl-33802584

15.

Response multilayered control of T cell receptor phosphorylation.

Gagnon, Etienne; Xu, Chenqi; Yang, Wei; Chu, H Hamlet; Call, Matthew E; Chou, James J; Wucherpfennig, Kai W.

Cell ; 142(5): 669-71, 2010 Sep 03.

Artigo Inglês | MEDLINE | ID: mdl-20813252

16.

Ion and inhibitor binding of the double-ring ion selectivity filter of the mitochondrial calcium uniporter.

Cao, Chan; Wang, Shuqing; Cui, Tanxing; Su, Xun-Cheng; Chou, James J.

Proc Natl Acad Sci U S A ; 114(14): E2846-E2851, 2017 04 04.

Artigo Inglês | MEDLINE | ID: mdl-28325874

17.

Critical Effect of the Detergent:Protein Ratio on the Formation of the Hepatitis C Virus p7 Channel.

Chen, Wen; OuYang, Bo; Chou, James J.

Biochemistry ; 58(37): 3834-3837, 2019 09 17.

Artigo Inglês | MEDLINE | ID: mdl-31468972

18.

Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain.

Peng, Ling; Zhang, Fengjuan; Shang, Renfu; Wang, Xueyan; Chen, Jiayi; Chou, James J; Ma, Jinbiao; Wu, Ligang; Huang, Ying.

J Biol Chem ; 293(26): 9981-9994, 2018 06 29.

Artigo Inglês | MEDLINE | ID: mdl-29703750

19.

Chen et al. reply.

Chen, Wen; OuYang, Bo; Chou, James J.

Nature ; 562(7727): E19-E20, 2018 10.

Artigo Inglês | MEDLINE | ID: mdl-30333581

20.

Unusual architecture of the p7 channel from hepatitis C virus.

OuYang, Bo; Xie, Shiqi; Berardi, Marcelo J; Zhao, Xinhao; Dev, Jyoti; Yu, Wenjing; Sun, Bing; Chou, James J.

Nature ; 498(7455): 521-5, 2013 Jun 27.

Artigo Inglês | MEDLINE | ID: mdl-23739335

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