Detalhe da pesquisa
1.
Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor.
Cell
; 175(6): 1520-1532.e15, 2018 11 29.
Artigo
Inglês
| MEDLINE | ID: mdl-30500536
2.
A molecular framework for temperature-dependent gating of ion channels.
Cell
; 158(5): 1148-1158, 2014 Aug 28.
Artigo
Inglês
| MEDLINE | ID: mdl-25156949
3.
cAMP binding to closed pacemaker ion channels is non-cooperative.
Nature
; 595(7868): 606-610, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34194042
4.
Targeted Protein Degradation via Lysosomes.
Biochemistry
; 62(3): 564-579, 2023 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36130224
5.
Elongation Factor P Modulates the Incorporation of Structurally Diverse Noncanonical Amino Acids into Escherichia coli Dihydrofolate Reductase.
J Am Chem Soc
; 145(43): 23600-23608, 2023 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37871253
6.
Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments.
Bioorg Med Chem Lett
; 29(1): 36-39, 2019 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30455147
7.
Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia.
Bioorg Med Chem
; 26(12): 3359-3369, 2018 07 23.
Artigo
Inglês
| MEDLINE | ID: mdl-29773347
8.
Lipophilic methylene violet analogues as modulators of mitochondrial function and dysfunction.
Bioorg Med Chem
; 25(20): 5537-5547, 2017 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28927904
9.
Synthesis and Evaluation of a Library of Fluorescent Dipeptidomimetic Analogues as Substrates for Modified Bacterial Ribosomes.
Biochemistry
; 55(17): 2427-40, 2016 May 03.
Artigo
Inglês
| MEDLINE | ID: mdl-27050631
10.
Protein Synthesis with Ribosomes Selected for the Incorporation of ß-Amino Acids.
Biochemistry
; 54(23): 3694-706, 2015 Jun 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25982410
11.
Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro.
J Am Chem Soc
; 137(35): 11206-9, 2015 Sep 09.
Artigo
Inglês
| MEDLINE | ID: mdl-26301427
12.
Synthesis of fluorescent dipeptidomimetics and their ribosomal incorporation into green fluorescent protein.
Bioorg Med Chem Lett
; 25(21): 4715-4718, 2015 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26351043
13.
Development of a PROTAC Targeting Chk1.
bioRxiv
; 2024 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38260247
14.
Lead Compound Development of SRC-3 Inhibitors with Improved Pharmacokinetic Properties and Anticancer Efficacy.
J Med Chem
; 67(7): 5333-5350, 2024 Apr 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38551814
15.
Incorporation of ß-amino acids into dihydrofolate reductase by ribosomes having modifications in the peptidyltransferase center.
Bioorg Med Chem
; 21(5): 1088-96, 2013 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23375097
16.
Deconstructing thermodynamic parameters of a coupled system from site-specific observables.
Proc Natl Acad Sci U S A
; 107(44): 18856-61, 2010 Nov 02.
Artigo
Inglês
| MEDLINE | ID: mdl-20944067
17.
Architecture and rearrangements of a sperm-specific Na+/H+ exchanger.
Res Sq
; 2023 Oct 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37886505
18.
High-resolution structures illuminate key principles underlying voltage and LRRC26 regulation of Slo1 channels.
bioRxiv
; 2023 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38187713
19.
Preclinical validation and treatment of volumetric modulated arc therapy based total bone marrow irradiation in Halcyon™ ring gantry linear accelerator.
Radiat Oncol
; 17(1): 145, 2022 Aug 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35986327
20.
Activation of the archaeal ion channel MthK is exquisitely regulated by temperature.
Elife
; 92020 12 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33274718