Detalhe da pesquisa
1.
Biographical Feature: Marc S. Collett (23 May 1951-11 June 2022): the Battle against Viral Disease Has Lost a Valiant Warrior, and the World Has Lost a Splendid Human Being.
J Virol
; 97(1): e0164322, 2023 01 31.
Artigo
Inglês
| MEDLINE | ID: mdl-36468860
2.
Negative feedback regulation of NF-κB-inducing kinase is proteasome-dependent but does not require cellular inhibitors of apoptosis.
Biochem Biophys Res Commun
; 450(1): 341-6, 2014 Jul 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24942881
3.
Smac mimetics activate the E3 ligase activity of cIAP1 protein by promoting RING domain dimerization.
J Biol Chem
; 286(19): 17015-28, 2011 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-21393245
4.
The discovery and structure-activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 21(11): 3227-31, 2011 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21550237
5.
Tilsotolimod with Ipilimumab Drives Tumor Responses in Anti-PD-1 Refractory Melanoma.
Cancer Discov
; 11(8): 1996-2013, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33707233
6.
The discovery and structure-activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 20(9): 2968-73, 2010 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20347591
7.
Molecular mechanism of hepatitis C virus replicon variants with reduced susceptibility to a benzofuran inhibitor, HCV-796.
Antimicrob Agents Chemother
; 52(9): 3327-38, 2008 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-18559648
8.
Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways.
Cell Death Differ
; 24(3): 481-491, 2017 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28106882
9.
Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models.
Mol Cancer Ther
; 13(4): 867-79, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24563541
10.
Birinapant, a smac-mimetic with improved tolerability for the treatment of solid tumors and hematological malignancies.
J Med Chem
; 57(9): 3666-77, 2014 May 08.
Artigo
Inglês
| MEDLINE | ID: mdl-24684347
11.
The novel SMAC mimetic birinapant exhibits potent activity against human melanoma cells.
Clin Cancer Res
; 19(7): 1784-94, 2013 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23403634
12.
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.
J Cell Biol
; 182(1): 171-84, 2008 Jul 14.
Artigo
Inglês
| MEDLINE | ID: mdl-18606850
13.
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.
Cell
; 131(4): 682-93, 2007 Nov 16.
Artigo
Inglês
| MEDLINE | ID: mdl-18022363
14.
Molecular mechanism of a thumb domain hepatitis C virus nonnucleoside RNA-dependent RNA polymerase inhibitor.
Antimicrob Agents Chemother
; 50(12): 4103-13, 2006 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-16940072
15.
Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymerase.
Antimicrob Agents Chemother
; 48(12): 4813-21, 2004 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-15561861
16.
The discovery of pyrano[3,4-b]indole-based allosteric inhibitors of HCV NS5B polymerase with in vivo activity.
ChemMedChem
; 3(10): 1508-15, 2008 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-18729128