Detalhe da pesquisa
1.
Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins.
Cell
; 153(1): 206-15, 2013 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23453757
2.
FOXM1 drives HPV+ HNSCC sensitivity to WEE1 inhibition.
Proc Natl Acad Sci U S A
; 117(45): 28287-28296, 2020 11 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33093209
3.
Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and ß-TrCP.
PLoS Pathog
; 15(1): e1007543, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30689667
4.
Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.
Proc Natl Acad Sci U S A
; 115(21): 5462-5467, 2018 05 22.
Artigo
Inglês
| MEDLINE | ID: mdl-29735700
5.
Fbw7 dimerization determines the specificity and robustness of substrate degradation.
Genes Dev
; 27(23): 2531-6, 2013 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24298052
6.
The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator.
Genes Dev
; 27(2): 151-6, 2013 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23322298
7.
NUP50 is necessary for the survival of primordial germ cells in mouse embryos.
Reproduction
; 151(1): 51-8, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26515778
8.
Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.
PLoS Biol
; 11(6): e1001586, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23776410
9.
Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation.
Proc Natl Acad Sci U S A
; 110(22): 8954-9, 2013 May 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23671119
10.
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
J Exp Med
; 204(8): 1813-24, 2007 Aug 06.
Artigo
Inglês
| MEDLINE | ID: mdl-17646409
11.
A mouse model for cyclin E-dependent genetic instability and tumorigenesis.
Cancer Cell
; 8(1): 35-47, 2005 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-16023597
12.
Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor.
Sci Adv
; 8(4): eabl7872, 2022 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35089787
13.
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.
Elife
; 112022 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35225231
14.
Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.
Nat Commun
; 12(1): 2043, 2021 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33824312
15.
A mechanism misregulating p27 in tumors discovered in a functional genomic screen.
PLoS Genet
; 3(12): e219, 2007 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-18069898
16.
A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation.
Sci Adv
; 6(16): eaaz9899, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32494624
17.
Cycling without CDK2?
Trends Cell Biol
; 13(8): 396-9, 2003 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-12888290
18.
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma.
J Cell Biol
; 167(5): 925-34, 2004 Dec 06.
Artigo
Inglês
| MEDLINE | ID: mdl-15583032
19.
Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice.
Sci Rep
; 9(1): 5488, 2019 04 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30940846
20.
RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions.
Nat Commun
; 9(1): 34, 2018 01 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29295984