Detalhe da pesquisa
1.
Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis.
Cell
; 174(4): 897-907.e14, 2018 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30078705
2.
Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome.
Cell
; 174(1): 231-244.e12, 2018 06 28.
Artigo
Inglês
| MEDLINE | ID: mdl-29804834
3.
An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing.
Mol Cell
; 2024 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38870936
4.
A central role for regulated protein stability in the control of TFE3 and MITF by nutrients.
Mol Cell
; 83(1): 57-73.e9, 2023 01 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36608670
5.
NEDD4L intramolecular interactions regulate its auto and substrate NaV1.5 ubiquitination.
J Biol Chem
; 300(3): 105715, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38309503
6.
CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II.
Mol Cell
; 68(3): 491-503.e5, 2017 Nov 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29056321
7.
A Tunable Brake for HECT Ubiquitin Ligases.
Mol Cell
; 66(3): 345-357.e6, 2017 May 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28475870
8.
The chemical biology of protein phosphorylation.
Annu Rev Biochem
; 78: 797-825, 2009.
Artigo
Inglês
| MEDLINE | ID: mdl-19489734
9.
Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Nature
; 558(7710): E1, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29769713
10.
Enzymatic analysis of WWP2 E3 ubiquitin ligase using protein microarrays identifies autophagy-related substrates.
J Biol Chem
; 298(5): 101854, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35331737
11.
Semisynthetic Approach to the Analysis of Tumor Suppressor PTEN Ubiquitination.
J Am Chem Soc
; 145(11): 6039-6044, 2023 03 22.
Artigo
Inglês
| MEDLINE | ID: mdl-36897111
12.
Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation.
J Am Chem Soc
; 145(12): 6811-6822, 2023 03 29.
Artigo
Inglês
| MEDLINE | ID: mdl-36930461
13.
Structural basis for the recognition of c-Src by its inactivator Csk.
Cell
; 134(1): 124-34, 2008 Jul 11.
Artigo
Inglês
| MEDLINE | ID: mdl-18614016
14.
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Nature
; 550(7674): 128-132, 2017 10 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28953875
15.
Histone H2B Deacylation Selectivity: Exploring Chromatin's Dark Matter with an Engineered Sortase.
J Am Chem Soc
; 144(8): 3360-3364, 2022 03 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35175758
16.
Ubiquitin Ligase Activities of WWP1 Germline Variants K740N and N745S.
Biochemistry
; 60(5): 357-364, 2021 02 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33470109
17.
Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases.
Bioorg Med Chem Lett
; 39: 127854, 2021 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33631370
18.
Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells.
Mol Cell
; 52(3): 314-24, 2013 Nov 07.
Artigo
Inglês
| MEDLINE | ID: mdl-24207025
19.
Site-Specific 5-Formyl Cytosine Mediated DNA-Histone Cross-Links: Synthesis and Polymerase Bypass by Human DNA Polymerase η.
Angew Chem Int Ed Engl
; 60(51): 26489-26494, 2021 12 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34634172
20.
Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases.
J Biol Chem
; 294(46): 17421-17436, 2019 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31578285