Detalhe da pesquisa
1.
Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: observation of extensive dynamics in an enzyme/inhibitor complex.
Bioorg Med Chem Lett
; 23(14): 4107-11, 2013 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23747226
2.
NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein.
J Med Chem
; 49(16): 5013-7, 2006 Aug 10.
Artigo
Inglês
| MEDLINE | ID: mdl-16884313
3.
Structural and functional characterization of CFE88: evidence that a conserved and essential bacterial protein is a methyltransferase.
Protein Sci
; 14(6): 1472-84, 2005 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-15929997
4.
Eleven amino acid glucagon-like peptide-1 receptor agonists with antidiabetic activity.
J Med Chem
; 52(23): 7788-99, 2009 Dec 10.
Artigo
Inglês
| MEDLINE | ID: mdl-19702274
5.
Multiple and single binding modes of fragment-like kinase inhibitors revealed by molecular modeling, residue type-selective protonation, and nuclear overhauser effects.
J Med Chem
; 51(19): 6225-9, 2008 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-18771253
6.
Observation of O-H...N scalar coupling across a hydrogen bond in nocathiacin I.
Magn Reson Chem
; 45(6): 447-50, 2007 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-17431856
7.
Protein-ligand NOE matching: a high-throughput method for binding pose evaluation that does not require protein NMR resonance assignments.
J Am Chem Soc
; 128(22): 7252-63, 2006 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-16734479
8.
Conformation and absolute configuration of nocathiacin I determined by NMR spectroscopy and chiral capillary electrophoresis.
J Am Chem Soc
; 124(25): 7284-5, 2002 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-12071733