Detalhe da pesquisa
1.
A Universal Eluent System for Method Scouting and Separation of Biotherapeutic Proteins by Ion-Exchange, Size-Exclusion, and Hydrophobic Interaction Chromatography.
Anal Chem
; 94(47): 16369-16375, 2022 11 29.
Artigo
Inglês
| MEDLINE | ID: mdl-36383642
2.
Characterization and Sequence Mapping of Large RNA and mRNA Therapeutics Using Mass Spectrometry.
Anal Chem
; 94(20): 7339-7349, 2022 05 24.
Artigo
Inglês
| MEDLINE | ID: mdl-35549087
3.
Rapid Highly-Efficient Digestion and Peptide Mapping of Adeno-Associated Viruses.
Anal Chem
; 93(30): 10403-10410, 2021 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34291903
4.
Inline electrochemical reduction of NISTmAb for middle-up subunit liquid chromatography-mass spectrometry analysis.
Analyst
; 146(21): 6547-6555, 2021 Oct 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34585175
5.
New Insights into the Chromatography Mechanisms of Ion-Exchange Charge Variant Analysis: Dispelling Myths and Providing Guidance for Robust Method Optimization.
Anal Chem
; 92(19): 13411-13419, 2020 10 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32970410
6.
Inter-laboratory study of an optimised peptide mapping workflow using automated trypsin digestion for monitoring monoclonal antibody product quality attributes.
Anal Bioanal Chem
; 412(25): 6833-6848, 2020 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-32710279
7.
Cracking Proteoform Complexity of Ovalbumin with Anion-Exchange Chromatography-High-Resolution Mass Spectrometry under Native Conditions.
J Proteome Res
; 18(10): 3689-3702, 2019 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31478673
8.
Charge Variant Analysis of Monoclonal Antibodies Using Direct Coupled pH Gradient Cation Exchange Chromatography to High-Resolution Native Mass Spectrometry.
Anal Chem
; 90(7): 4669-4676, 2018 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29494133
9.
A Novel Lipidomics Workflow for Improved Human Plasma Identification and Quantification Using RPLC-MSn Methods and Isotope Dilution Strategies.
Anal Chem
; 90(11): 6494-6501, 2018 06 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29708737
10.
Generic approach to the method development of intact protein separations using hydrophobic interaction chromatography.
J Sep Sci
; 41(5): 1017-1024, 2018 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-29178450
11.
Correction to Rapid Highly-Efficient Digestion and Peptide Mapping of Adeno-Associated Viruses.
Anal Chem
; 93(49): 16734, 2021 Dec 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34850630
12.
Anion exchange HPLC monitoring of mRNA in vitro transcription reactions to support mRNA manufacturing process development.
Front Mol Biosci
; 11: 1250833, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38516194
13.
Hydrophilic strong anion exchange (hSAX) chromatography for highly orthogonal peptide separation of complex proteomes.
J Proteome Res
; 12(6): 2449-57, 2013 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23294059
14.
Degradation of polysorbate investigated by a high-performance liquid chromatography multi-detector system with charged aerosol and mass detection.
J Chromatogr A
; 1710: 464405, 2023 Nov 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37769426
15.
Intact multi-attribute method (iMAM): A flexible tool for the analysis of monoclonal antibodies.
Eur J Pharm Biopharm
; 177: 241-248, 2022 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-35840072
16.
Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry.
Rapid Commun Mass Spectrom
; 25(22): 3447-52, 2011 Nov 30.
Artigo
Inglês
| MEDLINE | ID: mdl-22002700
17.
Optimisation of the use of sliding window deconvolution for comprehensive characterisation of trastuzumab and adalimumab charge variants by native high resolution mass spectrometry.
Eur J Pharm Biopharm
; 158: 83-95, 2021 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-33212184
18.
Proteomic Profiling of IgG1 Producing CHO Cells Using LC/LC-SPS-MS3: The Effects of Bioprocessing Conditions on Productivity and Product Quality.
Front Bioeng Biotechnol
; 9: 569045, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33898396
19.
Rational selection of reverse phase columns for high throughput LC-MS lipidomics.
Chem Phys Lipids
; 221: 120-127, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30940444
20.
Comprehensive characterisation of the heterogeneity of adalimumab via charge variant analysis hyphenated on-line to native high resolution Orbitrap mass spectrometry.
MAbs
; 11(1): 116-128, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30296204