Detalhe da pesquisa
1.
Mitomycin C inhibits ribosomal RNA: a novel cytotoxic mechanism for bioreductive drugs.
J Biol Chem
; 285(25): 19068-75, 2010 Jun 18.
Artigo
Inglês
| MEDLINE | ID: mdl-20418373
2.
The antitumor agent imexon activates antioxidant gene expression: evidence for an oxidative stress response.
Clin Cancer Res
; 13(11): 3388-94, 2007 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17545547
3.
Specific inhibition of the Akt1 pleckstrin homology domain by D-3-deoxy-phosphatidyl-myo-inositol analogues.
Mol Cancer Ther
; 2(4): 389-99, 2003 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-12700283
4.
Molecular and cellular characterization of imexon-resistant RPMI8226/I myeloma cells.
Mol Cancer Ther
; 1(3): 185-95, 2002 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-12467213
5.
In vivo molecular pharmacology and antitumor activity of the targeted Akt inhibitor PX-316.
Oncol Res
; 14(10): 513-27, 2004.
Artigo
Inglês
| MEDLINE | ID: mdl-15559765
6.
Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase.
Cancer Chemother Pharmacol
; 68(2): 405-13, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21069338
7.
Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity.
Arch Biochem Biophys
; 429(2): 123-33, 2004 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15313215