Detalhe da pesquisa
1.
Structure-activity relationships of tubulysin analogues.
Bioorg Med Chem Lett
; 30(14): 127241, 2020 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32527543
2.
CD4 mimetics sensitize HIV-1-infected cells to ADCC.
Proc Natl Acad Sci U S A
; 112(20): E2687-94, 2015 May 19.
Artigo
Inglês
| MEDLINE | ID: mdl-25941367
3.
Antibody-Dependent Cellular Cytotoxicity against Reactivated HIV-1-Infected Cells.
J Virol
; 90(4): 2021-30, 2016 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26656700
4.
Nonequilibrium dynamics of helix reorganization observed by transient 2D IR spectroscopy.
Proc Natl Acad Sci U S A
; 110(43): 17314-9, 2013 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24106309
5.
CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies.
J Virol
; 88(12): 6542-55, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24696475
6.
Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist.
Acc Chem Res
; 47(4): 1228-37, 2014 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24502450
7.
The design and synthesis of alanine-rich α-helical peptides constrained by an S,S-tetrazine photochemical trigger: a fragment union approach.
J Org Chem
; 79(2): 759-68, 2014 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-24359446
8.
Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity.
PLoS Pathog
; 7(6): e1002101, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21731494
9.
Di-Cysteine S,S-Tetrazine: A Potential Ultra-fast Photochemical Trigger to Explore the Early Events of Peptide/Protein Folding.
J Photochem Photobiol A Chem
; 234: 156-163, 2012 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22577259
10.
Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18.
Biochemistry
; 50(14): 2756-68, 2011 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-21351734
11.
Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state.
PLoS Pathog
; 5(4): e1000360, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19343205
12.
Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening.
Bioorg Med Chem
; 19(1): 91-101, 2011 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21169023
13.
Identification of a human immunodeficiency virus type 1 envelope glycoprotein variant resistant to cold inactivation.
J Virol
; 83(9): 4476-88, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-19211747
14.
Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.
Structure
; 16(11): 1689-701, 2008 Nov 12.
Artigo
Inglês
| MEDLINE | ID: mdl-19000821
15.
Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.
ACS Med Chem Lett
; 7(3): 330-4, 2016 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26985324
16.
Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity.
EBioMedicine
; 3: 122-134, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26870823
17.
Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.
EBioMedicine
; 12: 208-218, 2016 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-27633463
18.
Tetrazine phototriggers: probes for peptide dynamics.
Angew Chem Int Ed Engl
; 49(21): 3612-6, 2010 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-20391451
19.
Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions.
Science
; 346(6210): 759-63, 2014 Nov 07.
Artigo
Inglês
| MEDLINE | ID: mdl-25298114
20.
Crystal structures of HIV-1 gp120 envelope glycoprotein in complex with NBD analogues that target the CD4-binding site.
PLoS One
; 9(1): e85940, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24489681