Detalhe da pesquisa
1.
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.
N Engl J Med
; 387(12): 1099-1110, 2022 09 22.
Artigo
Inglês
| MEDLINE | ID: mdl-36129998
2.
Design and Statistical Innovations in a Platform Trial for Amyotrophic Lateral Sclerosis.
Ann Neurol
; 94(3): 547-560, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37245090
3.
Identification of gene fusions associated with amyotrophic lateral sclerosis.
Muscle Nerve
; 69(4): 477-489, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38305586
4.
Debamestrocel multimodal effects on biomarker pathways in amyotrophic lateral sclerosis are linked to clinical outcomes.
Muscle Nerve
; 69(6): 719-729, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38593477
5.
SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS.
N Engl J Med
; 383(2): 151-158, 2020 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32640133
6.
Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.
N Engl J Med
; 383(2): 109-119, 2020 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32640130
7.
Antibody Response to HML-2 May Be Protective in Amyotrophic Lateral Sclerosis.
Ann Neurol
; 92(5): 782-792, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36053951
8.
Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development.
Ann Neurol
; 91(2): 165-175, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34935174
9.
Effect of sodium phenylbutyrate and taurursodiol on plasma concentrations of neuroinflammatory biomarkers in amyotrophic lateral sclerosis: results from the CENTAUR trial.
J Neurol Neurosurg Psychiatry
; 2023 Dec 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38050066
10.
Safety and activity of anti-CD14 antibody IC14 (atibuclimab) in ALS: Experience with expanded access protocol.
Muscle Nerve
; 67(5): 354-362, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36533976
11.
Expanded access protocol (EAP) program for access to investigational products for amyotrophic lateral sclerosis (ALS).
Muscle Nerve
; 67(6): 456-463, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36929648
12.
Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis.
Muscle Nerve
; 67(5): 378-386, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36840949
13.
Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial.
J Neurol Neurosurg Psychiatry
; 2022 May 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35577511
14.
Survival analyses from the CENTAUR trial in amyotrophic lateral sclerosis: Evaluating the impact of treatment crossover on outcomes.
Muscle Nerve
; 66(2): 136-141, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35508892
15.
Phase 2B randomized controlled trial of NP001 in amyotrophic lateral sclerosis: Pre-specified and post hoc analyses.
Muscle Nerve
; 66(1): 39-49, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35098554
16.
A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis.
Muscle Nerve
; 65(3): 291-302, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34890069
17.
An expanded access protocol of RT001 in amyotrophic lateral sclerosis-Initial experience with a lipid peroxidation inhibitor.
Muscle Nerve
; 66(4): 421-425, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35765222
18.
Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis.
N Engl J Med
; 379(9): 846-855, 2018 08 30.
Artigo
Inglês
| MEDLINE | ID: mdl-30157388
19.
Gold Coast diagnostic criteria: Implications for ALS diagnosis and clinical trial enrollment.
Muscle Nerve
; 64(5): 532-537, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34378224
20.
Tocilizumab is safe and tolerable and reduces C-reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients.
Muscle Nerve
; 64(3): 309-320, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34075589