Mechanical comparison of straight and pre-bent interlocking nails used for the stabilization of a tibial gap fracture model.

OBJECTIVE: To compare the mechanical behavior of straight (STRT) and pre-bent (BENT) I-Loc angle-stable interlocking nails (AS-ILN) used for stabilization of canine mid-diaphyseal tibial fractures. STUDY DESIGN: In vitro experimental study. SAMPLE POPULATION: Tibial gap fracture models (n = 5/group). METHODS: Tibial models simulating a comminuted mid-diaphyseal fracture were stabilized with either a STRT or BENT I-Loc AS-ILN. Bent nails were contoured to match the 10° tibial recurvatum of a mid-size dog. Constructs were subjected to cyclic eccentric compressive loads followed by ramp load until failure. Construct compliance, maximum compressive load and resistive torque, yield load and angular deformation at 450 N were statistically compared using t-tests (p < .05). Failure modes were described. RESULTS: Compliance was 45% lower in BENT than STRT groups (p < .0001). Constructs in the BENT group sustained ~20% and 34% greater maximum and yield loads, respectively, than STRT constructs. Maximum resistive torques were similar between groups (p = .16). At 450 N, sagittal plane angular deformation increased from 0° to 4° in procurvatum (STRT group) and decreased from 10° to 8° in recurvatum (BENT group-p < .0001). Construct yield failure occurred at the nail isthmus in both groups. CONCLUSION: These results demonstrated that, in a tibial gap fracture model, pre-bending I-Loc AS-ILNs provided mechanical advantages by increasing their ability to resist bending resulting from eccentric compressive loads. CLINICAL SIGNIFICANCE: Pre-bending may reduce the occurrence of tibial nail yield failure. Surgeons should therefore consider pre-bending tibial I-Loc nails to match the bone anatomical recurvatum prior to implantation.

Prospective evaluation of the surgical stabilization and outcome of canine tibial plateau fractures in three cases.

OBJECTIVE: To report the surgical approaches and stabilization of lateral and medial tibial plateau fractures (TPF), as well as the long-term outcome following repair. STUDY DESIGN: Prospective series of three client-owned dogs. ANIMALS: Three dogs. METHODS: For the two lateral TPF cases (Unger type 41-B1), the surgical approach included separation of the lateral collateral ligament and long digital extensor tendon. The lateral meniscus was elevated to allow visualization of the tibial surface and assess fracture reduction. The first case was repaired using two 2.0 mm lag screws (with washers). The second case sustained a lateral TPF, fibular fracture and concurrent tubercle of Gerdy fracture. Both tibial fractures were stabilized using two 2.0 mm lag screws with washers and two 0.9 mm Kirschner wires (K-wires). A third case, diagnosed with an Unger type 41-B2 medial TPF, was treated using 0.9 mm K-wires and 22-gauge tension band. RESULTS: There were no major complications noted. One minor complication occurred (screw yield two weeks postoperatively). By 8 weeks, all patients reached clinical union with good limb function. Owners were contacted 9-36 months postoperatively. LOAD scores and examinations were performed for two of three patients; the third patient was not contactable after relocating out of state. Both cases with completed questionnaires had a LOAD score of 5/52. CONCLUSION: Tibial plateau fractures are rare in canine patients. While challenging, they can be successfully managed using a combination of lag screws, K-wires, and tension band. CLINICAL SIGNIFICANCE: Surgical stabilization of TPF is feasible and may reduce the risk of meniscal injury.

A comparison of the motor effects and analgesic efficacy following lumbar plexus block combined with sciatic nerve block or epidural in dogs undergoing tibial plateau leveling osteotomy.

OBJECTIVE: To compare motor effects and analgesic efficacy following an ultrasound-guided lateral approach to lumbar plexus blockade at L7 and sciatic nerve blockade (LPSNB) against epidural injection in dogs undergoing tibial plateau leveling osteotomy (TPLO). STUDY DESIGN: Prospective, randomized, blinded clinical trial. ANIMALS: A total of 27 healthy adult dogs undergoing unilateral TPLO surgery. METHODS: Dogs were allocated to either LPSNB (bupivacaine 2 mg kg-1, 0.75%) or epidural (morphine PF 0.1 mg kg-1 and bupivacaine 0.5 mg kg-1, 0.75%). Other aspects of clinical management were identical, including anesthetic drug protocol, area of presurgical clipping and bladder care. Time to perform the block, response to surgical stimuli, pain scores, rescue analgesia, time to stand and walk, motor score and time to first urination were recorded. One evaluator, unaware of treatment status, performed all evaluations. Student's t-test or Mann-Whitney U test was used to compare continuous variables between groups, and Fisher's exact test for categorical variables. RESULTS: Median (range) times to stand and walk were shorter for LPSNB [60 (40-120) minutes and 90 (60-150) minutes, respectively, p = 0.003] than for epidural [150 (120-240) minutes and 180 (120-360) minutes, respectively, p = 0.006]. Four dogs required rescue intraoperatively (three in epidural group, one in LPSNB group, p = 0.438). Pain scores over the 24 hour evaluation period were similar, and not significantly different, for each group. Time to spontaneous urination [LPSNB, 330 (240-360) minutes; epidural, 300 (120-1440) minutes, p = 1.0] did not differ between groups. CONCLUSIONS AND CLINICAL RELEVANCE: An ultrasound-guided lateral paravertebral approach to the lumbar plexus within the psoas compartment at L7, combined with sciatic nerve blockade, allows faster return to normal motor function, with similar pain control and impact on urination when compared with epidural in dogs after TPLO surgery.

Accuracy of anatomic 3-dimensionally printed canine humeral models.

OBJECTIVE: To evaluate the accuracy of various three-dimensional print (3DP) technologies using morphometric measurements. STUDY DESIGN: Experimental. SAMPLE POPULATION: Cadaveric canine humeri and size-matched 3DP models. METHODS: Fiduciary radiopaque markers were affixed to canine humeri of three different sizes (4, 13, 29 kg) at predetermined anatomical landmarks. 3DP models were created using one of three printers; desktop printers Form 3L and Ultimaker 5S, and industrial printer Objet Connex (n = 5/group/printer). Marker based morphometric dimensions between cadavers and 3DP models were statistically compared using 2-factor repeated measures ANOVA followed by Tukey's post-hoc test (p < .05). RESULTS: Bone size and printer type both significantly affected 3DP accuracy, with size having the larger effect (p < .0001 and p < .02, respectively). Regardless of printing technology, model size was smaller than native bone in most cases. At the humeral condylar level, the best accuracy was seen in the medium-sized humerus with the Ultimaker printer ([0.09 mm], p < .03). Accuracy was reduced in the proximal humerus in all groups. CONCLUSION: Desktop printers were overall more accurate than the industrial printer. Although significant differences were identified between models of different sizes, the submillimetric magnitude of these differences is unlikely to be clinically relevant. CLINICAL SIGNIFICANCE: While preoperative planning using 3DP models is becoming mainstream, accurate representation of the actual bone is critical. This study demonstrates that common desktop printers are suitable for this purpose.

Clinical application of the small I-Loc interlocking nail in 30 feline fractures: A prospective study.

OBJECTIVE: To describe medium-term functional outcome after nail osteosynthesis in feline traumatology and report clinically relevant recommendations for I-Loc angle-stable interlocking nail use in cats. STUDY DESIGN: Prospective clinical study. SAMPLE POPULATION: Client-owned cats (n = 29). METHODS: Consecutive cases with femoral, tibial, or humeral fractures were included. Outcome measures included fracture and surgical procedure description, limb alignment, nail size vs body weight (BW), percentage of nail medullary canal (MC) fill, time to limb function at clinical union (CU), and complications. Descriptive statistics were reported and compared with historical data. RESULTS: Bone distribution was 53.3% femora, 30% tibiae, and 16.7% humeri. There were six epimetaphyseal and 24 diaphyseal fractures. Overall, 67% of fractures were comminuted. Open reduction and minimally invasive techniques were used in 73% and 27% of cases, respectively. Seventeen I-Loc 3 (cat mean BW 4.4 ± 2.2 kg) and 13 I-Loc 4 (cat mean BW 5.2 ± 1.2 kg) nails were placed with mean MC fill of ≤50%. Average time to CU was 7.2 weeks. At CU, lameness had resolved or was mild in every cat, and all cats ultimately regained full limb function. No major complications were encountered. CONCLUSION: Because of improved CU times, excellent functional outcomes, and low complication rate, our results provide evidence that I-Loc nails are safe and effective for feline traumatology. CLINICAL SIGNIFICANCE: The I-Loc may be advantageous for fixation of epimetaphyseal fractures. Because of feline bone specific dimensional constraints, I-Loc 3 is likely appropriate for all feline humeri and most tibiae, while I-Loc 4 is well sized for feline femora.

Reconstruction of the cranial cruciate ligament using a semitendinosus autograft in a lapine model.

OBJECTIVE: To clarify and improve a cranial cruciate ligament (CrCL) deficient stifle stabilization technique using a semitendinosus tendon (ST) autograft fixed with an interference fit screw (IFS) in a closed-joint trauma lapine osteoarthritis (OA) model. STUDY DESIGN: Experimental OA model. ANIMALS: Forty-one Flemish Giant rabbits. METHODS: Following arthrotomy of traumatized lapine stifles, the ST insertion on the tibial plateau was exposed and the ST was transected near its origin. The graft was passed through tibial and femoral tunnels, manually tensioned and then secured in place with a custom IFS and periosteal sutures. Drawer was manually assessed during and immediately after surgery intraoperatively. Upon euthanasia, joint laxity was measured at 2, 10, or 22 weeks postoperatively and compared to that of the contralateral, intact stifles and stifles with a surgically transected CrCL. RESULTS: Minimal postoperative drawer was present in 34% of the rabbits and potentially correlated with meniscal injury and subsequent meniscectomy. CrCL reconstruction significantly reduced joint laxity to a level (3.6 ± 1.6 mm) similar to that (2.7 ± 0.8 mm) in contralateral intact stifles. CONCLUSION: Surgical replacement of a traumatically injured CrCL using a ST autograft fixed with an IFS replicated a common human surgical technique and effectively restored joint stability in the short, medium, and long terms of the study. CLINICAL SIGNIFICANCE: The study provides researchers a useful, clinically relevant, post-traumatic CrCL deficient rabbit model for the study of OA and investigations of interventions to mitigate or prevent long-term joint degeneration.

Mechanical comparison of two small interlocking nails in torsion using a feline bone surrogate.

OBJECTIVE: To compare the torsional behavior of two small angle-stable interlocking nails (I-Loc and Targon) with that of locking compression plates (LCP). To evaluate the effect of implant removal on the torsional strength of feline bone surrogates. STUDY DESIGN: Experimental. SAMPLE POPULATION: Fracture gap constructs and intact explanted bone surrogates. METHODS: Fracture gap constructs were stabilized with one of six implants (I-Loc 3 and 4, Targon 2.5 and 3.0, LCP 2.0 and 2.4) and then cyclically tested in torsion (n = 4/group). To simulate implant removal, intact surrogates with implant-specific pilot holes were then twisted to failure (n = 4/group). Torsional compliance (TC; °/Nm), angular deformation (AD; °), and failure torque (FT ; Nm) were statistically compared (P < .05). RESULTS: The I-Loc 4 had the smallest TC and AD of all constructs (P < .05). The largest TC (P < .05) was seen with the LCP 2.0. The Targon 2.5 had the largest AD (P < .05) secondary to locking interface slippage. Targon surrogates FT were the lowest of all groups (P < .05). Conversely, there was no difference between the FT of the I-Loc, LCP, and intact surrogates (P > .05). CONCLUSION: We showed that I-Loc nails provided greater torsional stability than size-matched Targon nails and LCPs. Conversely, Targon 2.5 locking interface slippage may jeopardize that construct's stability. Furthermore, the significantly reduced bone surrogate torsional strength provided evidence that the large Targon bolt holes increased the risk of postexplantation iatrogenic fracture. CLINICAL SIGNIFICANCE: Our results provide evidence to conclude that the small I-Loc nails may be valid alternatives to other osteosynthesis options for feline fracture repair.

Minimally invasive percutaneous medial plate rod osteosynthesis for treatment of bicondylar humeral fractures in dogs: Surgical technique and case report.

OBJECTIVE: To describe a minimally invasive surgical technique for the treatment of comminuted humeral bicondylar (also known as T-Y) fractures in dogs and report outcome in 3 cases. STUDY DESIGN: Surgical technique description and case report. ANIMALS: Three consecutive dogs with traumatic comminuted humeral T-Y fractures. METHODS: Dogs that presented with a traumatic humeral T-Y fracture were prospectively included. The condylar component of the fractures was reduced first by using a combination of percutaneous forceps and K-wires. A transcondylar screw was applied, and epicondylar pins were preplaced medially and laterally. The metaphyseal component of the fracture was then reduced and stabilized with the pins. Finally, a bone plate was applied percutaneously along the medial humeral surface. Intraoperative fluoroscopy was used throughout surgery in all cases. Postoperative alignment in the frontal and sagittal planes was compared to the contralateral limbs. Time to clinical union, clinical outcome, and complications were recorded. RESULTS: Three dogs were included. Body weight ranged from 5.9 to 40 kg. Incomplete ossification of the humeral condyle was identified as the primary pathology leading to the fracture in 2 cases. All cases experienced uncomplicated healing with good to excellent functional recovery. CONCLUSION: The reported technique was associated with good outcomes without complications in 3 cases. CLINICAL SIGNIFICANCE: This study provides evidence that minimally invasive plate osteosynthesis represents an alternative to open reduction and internal fixation in the treatment of comminuted humeral T-Y fractures.

Tibial fracture repair with angle-stable interlocking nailing in 2 calves.

OBJECTIVE: To report tibial fracture repairs with I-Loc angle-stable interlocking nails (AS-ILN) in 2 calves. STUDY DESIGN: Clinical case reports. ANIMALS: One 5-day-old Holstein calf and one 3-month-old beefalo calf. METHODS: In a 50-kg Holstein calf, a proximal juxtametaphyseal comminuted tibial fracture with tibial tuberosity slab fracture was repaired with an 8-160-mm I-Loc nail and 2 cortical lag screws. In an 89-kg beefalo calf, a long oblique middiaphyseal tibial fracture was repaired with an 8-185-mm I-Loc nail and 5 double loop cerclage wires. In each case, an I-Loc AS-ILN was selected because unique biomechanical challenges precluded treatment with traditional osteosynthesis methods, such as external coaptation or plate fixation. RESULTS: No complications were diagnosed, and clinical union was documented 4 weeks after surgery in both cases. Axial growth continued in both calves, with no evidence of angular limb deformity at 7- and 6-month follow-up. CONCLUSION: This is the first report describing the use of the I-Loc nail in a bovine species. This application led to uncomplicated healing of tibial fractures and continued growth in both young calves described here. CLINICAL SIGNIFICANCE: Interlocking nailing may provide an effective and safe alternative for osteosynthesis of tibial fractures in young calves. Insertion of the AS-ILN across the center of the proximal tibial physis of a rapidly growing calf does not seem to alter its growth potential.

Characterization of the torsional structural properties of feline femurs and surrogate bone models for mechanical testing of orthopedic implants.

OBJECTIVE: To characterize the torsional structural properties of the feline femur and design a bone model surrogate for mechanical testing of feline orthopedic implants. STUDY DESIGN: Experimental. SAMPLE POPULATION: Paired feline femurs (n = 30) and bone models (8 materials, n = 4/group). METHODS: Femurs were cyclically tested nondestructively in torsion and then loaded to failure. A generic femoral model was then designed from native femur dimensions and tested similarly by using 1 of 8 materials that were 3-dimensionally printed or machined. Outcome measures consisting of torsional compliance, angular deformation (AD), and torque to failure were compared by using Student's t test (P < .05). Failure modes are reported as descriptive statistics. RESULTS: Torsional compliance (1.6 ± 0.3°/Nm, 2.0 ± 0.1°/Nm), AD (3.1 ± 0.6°, 3.8 ± 0.2°) and torque to failure (7.8 ±1.2 Nm, 8.1 ± 1.3 Nm) did not differ between feline femurs and short-fiber epoxy (SFE) models. Conversely, most printed materials displayed excessive TC and failed by plastic deformation (AD > 15-fold that of native femurs) rather than by fracture. Feline bone and SFE both failed by spiral fractures. CONCLUSION: None of the outcome measures differed between the 4th generation SFE model and cadaveric femurs, but differences were identified between feline bone and printed materials. CLINICAL IMPACT: Machined SFE can be used to create a surrogate bone model with torsional structural properties similar to those of feline femurs. In contrast, common printable materials appear unsuitable to produce a realistic feline bone surrogate.

Minimally invasive percutaneous medial plate-rod osteosynthesis for treatment of humeral shaft fractures in dog and cats: Surgical technique and prospective evaluation.

OBJECTIVE: To describe and prospectively report outcomes associated with a novel minimally invasive percutaneous osteosynthesis (MIPO) technique for the treatment of humeral fractures in dogs and cats. STUDY DESIGN: Prospective clinical case series. ANIMALS: Eleven dogs and 4 cats with traumatic nonarticular humeral fractures. METHODS: Dogs and cats that presented with traumatic humeral fractures were enrolled in the study. After closed reduction, the fracture was stabilized by using a plate-rod combination applied via remote medial incisions. Postoperative alignment in the frontal and sagittal planes was statistically compared with the contralateral limbs. Time to clinical union and complications were also recorded. RESULTS: Eleven dogs and 4 cats were included in this study. Body weight ranged from 4.5 to 33.6 kg in dogs and from 2.2 to 3.6 kg in cats. A veterinary cuttable plate (6/11 dogs and 3/4 cats) or locking compression plate was used in a plate-rod configuration (11/11 dogs and 2/4 cats) or alone (2/4 cats). Rod-to-medullary-cavity ratio was 30%. Plate-span ratio was 5.8 (range, 2-13.5). No significant differences were found in frontal or sagittal plane alignment. Healing time in cases that completed on-time follow-up (12/15) was 36 ± 14 days (range, 20-69). No major complications were recorded. CONCLUSION: The reported technique was associated with good outcomes in a large variety of fracture configurations and animal sizes, with no complications. CLINICAL SIGNIFICANCE: This report provides evidence that MIPO is a compelling alternative to open reduction and internal fixation in the treatment of various humeral fractures.

Minimally invasive lag screw fixation of sacroiliac luxation/fracture using a dedicated novel instrument system: Apparatus and technique description.

OBJECTIVE: To describe a novel Sacroiliac Luxation Instrument System (SILIS™) and its application in minimally invasive osteosynthesis (MIO) of sacroiliac luxations/fractures (SIL/F). The SILIS was designed to provide stable SIL/F reduction and accurate sacral screw placement while reducing personnel exposure to ionizing radiation during intraoperative fluoroscopy. STUDY DESIGN: Descriptive, proof of concept cadaveric study. METHODS: A right SIL and a left SIL/F were created on a Labrador Retriever that had died of natural causes. Bilateral sacroiliac lag screw fixation was performed under fluoroscopic guidance with the SILIS, which consists of dedicated reduction and fixation instruments rigidly linked to table-bound 6-axis arms. RESULTS: Throughout surgery, the SILIS facilitated and maintained stable reduction and allowed accurate placement of a custom designed drill guide over the sacral body without the surgeon's manual holding of any reduction or fixation instruments. The surgical team was therefore able to step away from the C-arm when acquiring fluoroscopic images, thus reducing exposure to radiation. Dorsoventral and craniocaudal screw deviation from an ideal trajectory ranged from 0.9° to 3.8°. Both screws were fully located within the sacral body. CONCLUSION: The SILIS addresses limitations associated with MIO of SIL/F, including maintenance of reduction throughout surgery along with reliable and accurate sacral screw placement. Distance from the X-ray source is the most effective protection against radiation. Use of the SILIS allows the surgical team to move away from the C-arm during fluoroscopy, thereby reducing personnel exposure to dangerous direct and back-scattered ionizing radiation.

Effect of Intramedullary Rod Diameter on a String of Pearls Plate-Rod Construct in Mediolateral Bending: An In Vitro Mechanical Study.

OBJECTIVE: To evaluate the effect of intramedullary rod (IMR) diameter on the mechanical behavior of string of pearls (SOP) plate-rod constructs. STUDY DESIGN: In vitro mechanical study. SAMPLE POPULATION: Synthetic bone models (n = 24). METHODS: Locking 3.5 mm SOP plates were fixed to a tibial bone model with a 50 mm fracture gap. Four experimental groups (n = 4) were tested: monocortical SOP construct alone and monocortical SOP constructs augmented with a 2.4, 3.2, or 4.0 mm IMR corresponding to 24, 32, or 40% filling of the medullary cavity diameter (SOP-24, SOP-32, SOP-40). Control groups (n = 4) were stabilized with either a bicortical SOP plate (SOP-B) or a 3.5 mm limited contact dynamic compression plate (LC-DCP) with a 4.0 mm IMR filling 40% of the medullary cavity diameter (LC-DCP-40). Specimens were tested in mediolateral bending. Construct compliance (CC) and angular deformation (AD) were compared between construct types (P < .05). RESULTS: CC and AD incrementally decreased with increasing IMR diameter (P < .001). There were no statistical differences between SOP-24 and SOP-B (P = .806) or between SOP-32 and LC-DCP-40 (P = .773), which was also the least compliant of all constructs (P < .001). AD followed an identical pattern of significance. CONCLUSIONS: Biological osteosynthesis often relies on more compliant bridging constructs to promote beneficial micromotion at the fracture. Our study suggests use of a smaller diameter IMR (SOP-32) is comparable to a conventional plate-rod construct (LC-DCP-40). Should greater compliance be desired, an even smaller diameter IMR (SOP-24) may prove beneficial while as stable as an accepted bicortical construct (SOP-B).

Effect of screw type and distribution on the torsional stability of 3.5 mm string of pearls locking plate constructs.

OBJECTIVE: To evaluate the effects of screw type (mono- [M] versus bicortical [B]), number, and position on torsional stability of String of Pearls (SOP) locking plate constructs. STUDY DESIGN: In vitro mechanical study. METHODS: SOP plates (n = 32) were applied to bone models and divided into 8 groups named according to screw type (M or B) and position in each fragment relative to the fracture gap starting at the outermost plate hole. Positive and negative controls were MMM and BBB, respectively. Specimens were non-destructively tested in torsion. Compliance and angular deformation were statistically compared (P < .002). RESULTS: The MMM construct was most compliant (P < .001). Compliance decreased in groups with a single bicortical screw (P < .001). Compared to the MMM group, torsional compliance decreased in constructs where a single monocortical screw was replaced with a bicortical screw (P < .001). Compared with a centrally positioned bicortical screw, constructs with a bicortical screw in either outer- or innermost position were 15% and 23% less compliant, respectively (P < .001). Addition of a second bicortical screw/fragment further decreased compliance (P < .001). No significant difference was found between groups with 2 bicortical screws. The BBB construct was least compliant (P < .001). Group responses for angular deformation followed the same pattern of significance recorded for compliance. CONCLUSIONS: A minimum of 1 bicortical screw/fragment should be used to increase torsional stability of 3.5 mm SOP constructs. Positioning this screw at the inner- or outermost positions relative to the fracture is preferred, with the innermost position providing the greatest improvement in stability. Should further torsional stability be desired, increasing the number of bicortical screws is recommended. Clinically, these results may assist with preoperative planning of various fracture patterns.

Less invasive unilateral arytenoid lateralization: a modified technique for treatment of idiopathic laryngeal paralysis in dogs: technique description and outcome.

OBJECTIVE: To (1) describe a modification of conventional unilateral cricoarytenoid lateralization (UCAL), called less-invasive unilateral cricoarytenoid lateralization (LI-UCAL) for treatment of idiopathic laryngeal paralysis (LP); (2) report clinical outcome of LI-UCAL; and (3) describe the effect of early discharge after surgery. STUDY DESIGN: Retrospective clinical study. ANIMALS: Dogs (n = 22). METHODS: Medical records (January 2009 to October 2011) of dogs diagnosed with idiopathic LP that had LI-UCAL were reviewed. Signalment, clinical signs, laboratory tests, imaging, concurrent medical conditions, information from the anesthesia record, and hospitalization time were documented. Follow-up was obtained by direct examination, questionnaire, and review of medical records from referring veterinarians. RESULTS: Dogs included in the study had variable degrees and duration of respiratory distress before surgery. Median surgery time was 32 minutes. Median hospitalization was 6 hours, and median follow-up was 427 days. Long-term respiratory function, as reported by owners at last follow-up, improved in 95.5% of dogs after surgery; exercise tolerance improved by 90%. Major complications included death secondary to aspiration pneumonia (9%), aspiration pneumonia from which dogs recovered within 3 days after administration of antimicrobials (9%), and development of right-sided laryngeal collapse that required right sided LI-UCAL (4.5%). At long-term follow-up, 95.5% of owners were satisfied with the surgical outcome. CONCLUSION: LI-UCAL is a feasible surgical technique and resulted in improvement of clinical signs related to LP. Calm recoveries without adverse effects such as respiratory distress were associated with early discharge. LI-UCAL could be considered an alternative to conventional UCAL.

In vivo biomechanical evaluation of a novel angle-stable interlocking nail design in a canine tibial fracture model.

OBJECTIVE: To compare clinical outcome and callus biomechanical properties of a novel angle stable interlocking nail (AS-ILN) and a 6 mm bolted standard ILN (ILN6b) in a canine tibial fracture model. STUDY DESIGN: Experimental in vivo study. ANIMALS: Purpose-bred hounds (n = 11). METHODS: A 5 mm mid-diaphyseal tibial ostectomy was stabilized with an AS-ILN (n = 6) or an ILN6b (n = 5). Orthopedic examinations and radiographs were performed every other week until clinical union (18 weeks). Paired tibiae were tested in torsion until failure. Callus torsional strength and toughness were statistically compared and failure mode described. Total and cortical callus volumes were computed and statistically compared from CT slices of the original ostectomy gap. Statistical significance was set at P < .05 RESULTS: From 4 to 8 weeks, lameness was less pronounced in AS-ILN than ILN6b dogs (P < .05). Clinical union was reached in all AS-ILN dogs by 10 weeks and in 3/5 ILN6b dogs at 18 weeks. Callus mechanical properties were significantly greater in AS-ILN than ILN6b specimens by 77% (failure torque) and 166% (toughness). Failure occurred by acute spiral (control and AS-ILN) or progressive transverse fractures (ILN6b). Cortical callus volume was 111% greater in AS-ILN than ILN6b specimens (P < .05). CONCLUSIONS: Earlier functional recovery, callus strength and remodeling suggest that the AS-ILN provides a postoperative biomechanical environment more conducive to bone healing than a comparable standard ILN.

Effect of screw insertion torque on mechanical properties of four locking systems.

OBJECTIVE: To evaluate the effect of screw insertion torque on the mechanical properties of four 3.5 mm locking systems: New Generation Devices (NGD), Securos (PAX), Synthes (SYN), and Veterinary Orthopedic Implants (VOI). STUDY DESIGN: In vitro mechanical study. METHODS: Screws were inserted at 1.5 Nm, 2.5 Nm, and 3.5 Nm torques, using dedicated drill guides and a calibrated torque screwdriver. Locking mechanisms were tested under shear loading conditions using a custom-design probe. Tests were conducted under displacement control until failure. Load to failure and interface stiffness were compared between and within groups using a two-factor ANOVA (P < .05). Failure modes were described. RESULTS: The SYN group had significantly greater mechanical properties compared to all other groups at any given insertion torque. Insertion torque had a significant effect on the PAX group, increasing the load to failure by 126% when increasing the insertion torque from 1.5 Nm to 3.5 Nm. Insertion torque had no significant effect on the mechanical properties of the VOI group and limited effect on the NGD and SYN groups. Single failure mode, by screw head decoupling or screw shaft fracture, occurred in the SYN and VOI groups, respectively. In contrast, NGD and PAX systems failed through a combination of screw decoupling and/or bending. CONCLUSIONS: Regardless of insertion torque, the SYN locking mechanism showed the highest failure loads, interfacial stiffness as well as consistent failure mode. These findings highlight the dependability of this system. When using the PAX system an insertion torque of at least 2.5 Nm should be recommended.

Post-sterilization Dimensional Accuracy of Methacrylate Monomer Biocompatible Three-Dimensionally Printed Mock Surgical Guides.

OBJECTIVES: The aim of this study was to evaluate the post-sterilization dimensional accuracy of a standardized drilling guide, three-dimensionally printed using biocompatible methacrylate monomers. STUDY DESIGN: A mock surgical guide was designed and printed in five resins (n = 5/material) using a commercially available desktop stereolithography printer. Pre- and post-sterilization dimensions were measured for each sterilization method (steam, ethylene oxide, hydrogen peroxide gas), then statistically compared; p-value less than or equal 0.05 was considered significant. RESULTS: While all resins produced highly accurate replicas of the designed guide, the amber and black resins were unaffected by any sterilization method (p ≥ 0.9). For other materials, ethylene oxide produced the largest dimensional changes. However, mean post-sterilization dimensional changes for all materials and sterilization methods remained less than or equal to 0.05mm CONCLUSION: This study demonstrated that post-sterilization dimensional change of evaluated biomaterials was minimal, and less than previously reported. Additionally, amber and black resins may be preferred to reduce post-sterilization dimensional change, as they were unaffected by any sterilization method. Given the results of this study, surgeons should feel confident using the Form 3B printer to create patient surgical guides. Furthermore, bioresins may provide safer alternatives for patients compared with other three-dimensional printed materials.

Mechanical assessment of two hybrid plate designs for pancarpal canine arthrodesis under cyclic loading.

Pancarpal canine arthrodesis (PCA) sets immobilization of all three carpal joints via dorsal plating to result in bony fusion. Whereas the first version of the plate uses a round hole (RH) for the radiocarpal (RC) screw region, its modification into an oval hole (OH) in a later version improves versatility in surgical application. The aim of this study was to mechanically investigate the fatigue life of the PCA plate types implementing these two features-PCA-RH and PCA-OH. Ten PCA-RH and 20 PCA-OH stainless steel (316LVM) plates were assigned to three study groups (n = 10). All plates were pre-bent at 20° and fixed to a canine forelimb model with simulated radius, RC bone and third metacarpal bone. The OH plates were fixed with an RC screw inserted either most proximal (OH-P) or most distal (OH-D). All specimens were cyclically tested at 8 Hz under 320 N loading until failure. Fatigue life outcome measures were cycles to failure and failure mode. Cycles to failure were higher for RH plate fixation (695,264 ± 344,023) versus both OH-P (447,900 ± 176,208) and OH-D (391,822 ± 165,116) plate configurations, being significantly different between RH and OH-D, p = 0.03. No significant difference was detected between OH-P and OH-D configurations, p = 0.09. Despite potential surgical advantages, the shorter fatigue life of the PCA-OH plate design may mitigate its benefits compared to the plate design with a round radiocarpal screw hole. Moreover, the failure risk of plates with an oval hole is increased regardless from the screw position in this hole. Based on these findings, the PCA plate with the current oval radiocarpal screw hole configuration cannot be recommended for clinical use.