Detalhe da pesquisa
1.
Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice.
PLoS Pathog
; 18(5): e1010498, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35587469
2.
Capillary electrokinetic chromatography for chiral separation of potential SARS-CoV-2 3CL protease inhibitors.
Electrophoresis
; 2024 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38225719
3.
Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis.
Angew Chem Int Ed Engl
; 61(39): e202203560, 2022 09 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35904863
4.
FastTargetPred: a program enabling the fast prediction of putative protein targets for input chemical databases.
Bioinformatics
; 36(14): 4225-4226, 2020 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32399567
5.
Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry.
Molecules
; 26(19)2021 Oct 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34641626
6.
NMR Spectroscopy of the Main Protease of SARS-CoV-2 and Fragment-Based Screening Identify Three Protein Hotspots and an Antiviral Fragment.
Angew Chem Int Ed Engl
; 60(48): 25428-25435, 2021 11 22.
Artigo
Inglês
| MEDLINE | ID: mdl-34570415
7.
Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study.
Lancet
; 391(10115): 59-69, 2018 01 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29107324
8.
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.
Acta Neuropathol
; 138(4): 631-652, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31065832
9.
Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis.
Bioorg Med Chem
; 26(4): 945-956, 2018 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28818461
10.
Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.
Acta Neuropathol
; 133(6): 955-966, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27933404
11.
Identification of novel TACE inhibitors compatible with topical application.
Bioorg Med Chem Lett
; 27(8): 1848-1853, 2017 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28274635
12.
Characterization of monoclonal antibodies by a fast and easy liquid chromatography-mass spectrometry time-of-flight analysis on culture supernatant.
Anal Biochem
; 491: 52-4, 2015 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26302360
13.
Unconventional surface plasmon resonance signals reveal quantitative inhibition of transcriptional repressor EthR by synthetic ligands.
Anal Biochem
; 452: 54-66, 2014 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24561027
14.
Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands.
Nucleic Acids Res
; 40(7): 3018-30, 2012 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-22156370
15.
Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae.
EMBO Mol Med
; 16(1): 93-111, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38177534
16.
Structural and docking studies of potent ethionamide boosters.
Acta Crystallogr C
; 69(Pt 11): 1243-50, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24192167
17.
Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers' Lactamization.
Pharmaceuticals (Basel)
; 16(3)2023 Mar 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36986512
18.
Migration study of phthalates from non-food plastic containers used in food preservation.
Heliyon
; 9(9): e20002, 2023 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-37809712
19.
Exploring the Antitubercular Activity of Anthranilic Acid Derivatives: From MabA (FabG1) Inhibition to Intrabacterial Acidification.
Pharmaceuticals (Basel)
; 16(3)2023 Feb 22.
Artigo
Inglês
| MEDLINE | ID: mdl-36986435
20.
High-Throughput Quantitative Screening of Glucose-Stimulated Insulin Secretion and Insulin Content Using Automated MALDI-TOF Mass Spectrometry.
Cells
; 12(6)2023 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36980190