Detalhe da pesquisa
1.
Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells.
Cell Biol Toxicol
; 39(4): 1773-1793, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36586010
2.
SAR exploration of the non-imidazole histamine H3 receptor ligand ZEL-H16 reveals potent inverse agonism.
Arch Pharm (Weinheim)
; 356(1): e2200451, 2023 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-36310109
3.
Fragment Screening Yields a Small-Molecule Stabilizer of 14-3-3 Dimers That Modulates Client Protein Interactions.
Chembiochem
; 23(17): e202200178, 2022 09 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35767695
4.
A Photoswitchable Agonist for the Histamine H3 Receptor, a Prototypic Family A G-Protein-Coupled Receptor.
Angew Chem Int Ed Engl
; 58(14): 4531-4535, 2019 03 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30735597
5.
Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology.
J Am Chem Soc
; 140(12): 4232-4243, 2018 03 28.
Artigo
Inglês
| MEDLINE | ID: mdl-29470065
6.
Photoswitching the Efficacy of a Small-Molecule Ligand for a Peptidergic GPCR: from Antagonism to Agonism.
Angew Chem Int Ed Engl
; 57(36): 11608-11612, 2018 09 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29926530
7.
Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.
Proc Natl Acad Sci U S A
; 110(22): 8894-9, 2013 May 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23676274
8.
Structural and Molecular Determinants for Isoform Bias at Human Histamine H3 Receptor Isoforms.
ACS Chem Neurosci
; 14(4): 645-656, 2023 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36702158
9.
Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms.
PLoS Negl Trop Dis
; 17(8): e0011564, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37590328
10.
Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3.
ACS Chem Biol
; 17(11): 2972-2978, 2022 11 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36255265
11.
Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability.
Sci Rep
; 11(1): 11575, 2021 06 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34078926
12.
4-(3-Aminoazetidin-1-yl)pyrimidin-2-amines as High-Affinity Non-imidazole Histamine H3 Receptor Agonists with in Vivo Central Nervous System Activity.
J Med Chem
; 62(23): 10848-10866, 2019 12 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31675226