RESUMO
One hundred fifty-three lung lavage procedures were performed on 81 cystic fibrosis patients during the years 1963 to 1976. Local analgesia was used in 24 lavages done via a rigid bronchoscope and in a group of 73 lavages directed by a fiberoptic bronchoscope. No abnormalities in cardiac rate or rhythm were observed with the lavages directed by fiberoptic bronchoscope. Fifty-six lavages were performed under general anesthesia with 20 cardiac abnormalities being noted among this group. Subjective improvement was noted in 96% of the 56 patients who had lavage under general anesthesia. Objective improvement was apparent in 45% of the 24 patients who had lavage with the rigid bronchoscope and 64% of the 36 patients who had lavage by fiberoptic bronchoscopy. It is concluded that patients with cystic fibrosis of varying stages of disability can more safety (and with good improvement) have bronchial washouts with the fiber-optic bronchoscope than with either of the other two techniques.
Assuntos
Fibrose Cística/terapia , Irrigação Terapêutica/métodos , Adolescente , Adulto , Anestesia Geral , Anestesia Local , Gasometria , Broncoscopia/efeitos adversos , Broncoscopia/métodos , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Irrigação Terapêutica/efeitos adversos , Capacidade VitalRESUMO
The water-soluble benzodiazepine, midazolam, was administered epidurally over the lumbar enlargement 18 times to 9 patients with spasticity due to severe spinal cord injury. Doses of 1.25-3.75 mg produced a rapid decrease of spasticity which lasted 1 h. After the maximal reduction of spasticity, the patients became drowsy. While the results suggest a direct action of midazolam on the spinal cord to reduce spasticity, the effect does not contribute to its usefulness as a therapeutic tool.
Assuntos
Midazolam/uso terapêutico , Espasticidade Muscular/tratamento farmacológico , Adulto , Relação Dose-Resposta a Droga , Humanos , Injeções Epidurais , Masculino , Midazolam/administração & dosagem , Espasticidade Muscular/etiologia , Traumatismos da Medula Espinal/complicaçõesRESUMO
The American Academy of Pediatrics proposes the following guidelines for the pediatric perioperative anesthesia environment. Essential components are identified that make the perioperative environment satisfactory for the anesthesia care of infants and children. Such an environment promotes the safety and wellbeing of infants and children by reducing the risk for adverse events.