Detalhe da pesquisa
1.
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches.
Cell
; 185(2): 379-396.e38, 2022 01 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35021063
2.
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Nature
; 615(7953): 678-686, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36922586
3.
A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Nature
; 598(7881): 504-509, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34616043
4.
A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate.
Nature
; 590(7845): 320-325, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33260195
5.
Animal models for COVID-19.
Nature
; 586(7830): 509-515, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32967005
6.
YF17D-based vaccines - standing on the shoulders of a giant.
Eur J Immunol
; 54(5): e2250133, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38571392
7.
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity.
Proc Natl Acad Sci U S A
; 117(43): 26955-26965, 2020 10 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33037151
8.
Publisher Correction: A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Nature
; 599(7883): E2, 2021 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-34671169
9.
Viral engagement with host receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid.
PLoS Pathog
; 15(5): e1007760, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31071193
10.
Identification of host factors binding to dengue and Zika virus subgenomic RNA by efficient yeast three-hybrid screens of the human ORFeome.
RNA Biol
; 18(5): 732-744, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33459164
11.
The Development of RNA-KISS, a Mammalian Three-Hybrid Method to Detect RNA-Protein Interactions in Living Mammalian Cells.
J Proteome Res
; 19(7): 2529-2538, 2020 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32216351
12.
Efficient control of Japanese encephalitis virus in the central nervous system of infected pigs occurs in the absence of a pronounced inflammatory immune response.
J Neuroinflammation
; 17(1): 315, 2020 Oct 23.
Artigo
Inglês
| MEDLINE | ID: mdl-33097065
13.
Towards rabies elimination in the Asia-Pacific region: From theory to practice.
Biologicals
; 64: 83-95, 2020 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-32089431
14.
Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication.
J Hepatol
; 64(3): 565-73, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26626494
15.
Hepatitis E virus mutations associated with ribavirin treatment failure result in altered viral fitness and ribavirin sensitivity.
J Hepatol
; 65(3): 499-508, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27174035
16.
Flaviviral NS4b, chameleon and jack-in-the-box roles in viral replication and pathogenesis, and a molecular target for antiviral intervention.
Rev Med Virol
; 25(4): 205-23, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25828437
17.
A mutation in the hepatitis E virus RNA polymerase promotes its replication and associates with ribavirin treatment failure in organ transplant recipients.
Gastroenterology
; 147(5): 1008-11.e7; quiz e15-6, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25181691
18.
Ribavirin inhibits in vitro hepatitis E virus replication through depletion of cellular GTP pools and is moderately synergistic with alpha interferon.
Antimicrob Agents Chemother
; 58(1): 267-73, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24145541
19.
Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral.
J Antimicrob Chemother
; 69(10): 2770-84, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-24951535
20.
Zika genomics urgently need standardized and curated reference sequences.
PLoS Pathog
; 13(9): e1006528, 2017 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28880955