Detalhe da pesquisa
1.
Structure and dynamics of G protein-coupled receptor-bound ghrelin reveal the critical role of the octanoyl chain.
Proc Natl Acad Sci U S A
; 116(35): 17525-17530, 2019 08 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31416915
2.
Biotinylated non-ionic amphipols for GPCR ligands screening.
Methods
; 180: 69-78, 2020 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32505829
3.
GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation.
Proc Natl Acad Sci U S A
; 115(17): 4501-4506, 2018 04 24.
Artigo
Inglês
| MEDLINE | ID: mdl-29632174
4.
Illuminating the Energy Landscape of GPCRs: The Key Contribution of Solution-State NMR Associated with Escherichia coli as an Expression Host.
Biochemistry
; 57(16): 2297-2307, 2018 04 24.
Artigo
Inglês
| MEDLINE | ID: mdl-29607648
5.
Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex.
Proc Natl Acad Sci U S A
; 112(5): 1601-6, 2015 Feb 03.
Artigo
Inglês
| MEDLINE | ID: mdl-25605885
6.
Fluorescence Study of Imidazoquinoxalines.
J Fluoresc
; 27(5): 1607-1611, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28470378
7.
Detergent-free Isolation of Functional G Protein-Coupled Receptors into Nanometric Lipid Particles.
Biochemistry
; 55(1): 38-48, 2016 Jan 12.
Artigo
Inglês
| MEDLINE | ID: mdl-26701065
8.
Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling.
J Biol Chem
; 290(45): 27021-27039, 2015 Nov 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26363071
9.
Functional Modulation of a G Protein-Coupled Receptor Conformational Landscape in a Lipid Bilayer.
J Am Chem Soc
; 138(35): 11170-5, 2016 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27489943
10.
New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center.
Bioorg Med Chem Lett
; 26(10): 2408-2412, 2016 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27072910
11.
Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor.
Proc Natl Acad Sci U S A
; 109(21): 8304-9, 2012 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-22573814
12.
Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy.
Proc Natl Acad Sci U S A
; 109(17): 6733-8, 2012 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-22493271
13.
Heterodimerization with Its splice variant blocks the ghrelin receptor 1a in a non-signaling conformation: a study with a purified heterodimer assembled into lipid discs.
J Biol Chem
; 288(34): 24656-65, 2013 Aug 23.
Artigo
Inglês
| MEDLINE | ID: mdl-23839942
14.
Amphipols in G protein-coupled receptor pharmacology: what are they good for?
J Membr Biol
; 247(9-10): 853-60, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-24801284
15.
High constitutive activity is an intrinsic feature of ghrelin receptor protein: a study with a functional monomeric GHS-R1a receptor reconstituted in lipid discs.
J Biol Chem
; 287(6): 3630-41, 2012 Feb 03.
Artigo
Inglês
| MEDLINE | ID: mdl-22117076
16.
How ligands and signalling proteins affect G-protein-coupled receptors' conformational landscape.
Biochem Soc Trans
; 41(1): 144-7, 2013 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23356274
17.
Non-ionic cholesterol-based additives for the stabilization of membrane proteins.
Biochimie
; 205: 27-39, 2023 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-36586567
18.
Sodium is a negative allosteric regulator of the ghrelin receptor.
Cell Rep
; 42(4): 112320, 2023 04 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37027306
19.
MT1 Melatonin Receptor Reconstitution in Nanodiscs.
Methods Mol Biol
; 2550: 171-178, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36180690
20.
Exploration of the dynamic interplay between lipids and membrane proteins by hydrostatic pressure.
Nat Commun
; 13(1): 1780, 2022 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35365643