Detalhe da pesquisa
1.
Identification of SARS-CoV-2 PLpro and 3CLpro human proteome substrates using substrate phage display coupled with protein network analysis.
J Biol Chem
; 299(6): 104831, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37201587
2.
Novel Engineered SARS-CoV-2 HR1 Trimer Exhibits Improved Potency and Broad-Spectrum Activity against SARS-CoV-2 and Its Variants.
J Virol
; 96(13): e0068122, 2022 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-35735997
3.
SNAC-tag for sequence-specific chemical protein cleavage.
Nat Methods
; 16(4): 319-322, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30923372
4.
A disease-associated mutation in fibrillin-1 differentially regulates integrin-mediated cell adhesion.
J Biol Chem
; 294(48): 18232-18243, 2019 11 29.
Artigo
Inglês
| MEDLINE | ID: mdl-31640988
5.
Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates.
J Am Chem Soc
; 142(51): 21310-21321, 2020 12 23.
Artigo
Inglês
| MEDLINE | ID: mdl-33301681
6.
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures.
Proc Natl Acad Sci U S A
; 114(41): 10852-10857, 2017 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28973862
7.
Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET.
Proc Natl Acad Sci U S A
; 114(10): E1857-E1865, 2017 03 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28202723
8.
Reinvestigation of the biological activity of d-allo-ShK protein.
J Biol Chem
; 292(30): 12599-12605, 2017 07 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28596383
9.
Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin.
Angew Chem Int Ed Engl
; 56(12): 3324-3328, 2017 03 13.
Artigo
Inglês
| MEDLINE | ID: mdl-28194851
10.
Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
Angew Chem Int Ed Engl
; 55(30): 8639-42, 2016 07 18.
Artigo
Inglês
| MEDLINE | ID: mdl-27244051
11.
Total chemical synthesis of biologically active fluorescent dye-labeled Ts1 toxin.
Angew Chem Int Ed Engl
; 53(34): 8970-4, 2014 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24989851
12.
An enhanced broad-spectrum peptide inhibits Omicron variants in vivo.
Cell Rep Med
; 5(2): 101418, 2024 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38340726
13.
Native chemical ligation at Asx-Cys, Glx-Cys: chemical synthesis and high-resolution X-ray structure of ShK toxin by racemic protein crystallography.
J Am Chem Soc
; 135(32): 11911-9, 2013 Aug 14.
Artigo
Inglês
| MEDLINE | ID: mdl-23919482
14.
A high-throughput fully automatic biosensing platform for efficient COVID-19 detection.
Biosens Bioelectron
; 220: 114861, 2023 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36347077
15.
Copper assisted sequence-specific chemical protein conjugation at a single backbone amide.
Nat Commun
; 14(1): 8063, 2023 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38052794
16.
Precise control of embolic stroke with magnetized red blood cells in mice.
Commun Biol
; 5(1): 136, 2022 02 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35173272
17.
Nav channel binder containing a specific conjugation-site based on a low toxicity ß-scorpion toxin.
Sci Rep
; 7(1): 16329, 2017 11 27.
Artigo
Inglês
| MEDLINE | ID: mdl-29180755
18.
Enhanced trimeric ACE2 exhibits potent prophylactic and therapeutic efficacy against the SARS-CoV-2 Delta and Omicron variants in vivo.
Cell Res
; 32(6): 589-592, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35418217
19.
Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions.
Nat Commun
; 8(1): 2240, 2017 12 21.
Artigo
Inglês
| MEDLINE | ID: mdl-29269770
20.
Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection.
Cell Res
; 31(1): 98-100, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33177651