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1.
J Biol Regul Homeost Agents ; 33(5 Suppl. 1): 53-58. Special Issue: Focus on Pediatric Nephrology, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31630714

RESUMO

Nocturnal enuresis (NE) was defined by the World Health Organization (ICD-10) and the American Psychiatric Association (DSM-5) as bed-wetting in children aged >5 years. In cases of mental retardation, the developmental age may be equivalent to 5 years. In this review, we focus on the current knowledge about the etiology of enuresis and the most recent therapeutical options. Both non-pharmacological and pharmacological therapies are included, although the relative effectiveness of each remains uncertain. To date, motivational, alarm and drug therapies are the mainstay of treatment. Alarm therapy remains the first-line treatment modality for NE, while desmopressin is the most commonly used medical treatment.


Assuntos
Rim/patologia , Enurese Noturna/diagnóstico , Enurese Noturna/terapia , Desamino Arginina Vasopressina/uso terapêutico , Humanos , Recém-Nascido
3.
Chem Commun (Camb) ; (33): 3927-9, 2008 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-18726037

RESUMO

N-Benzyloxyethyl cyclic alpha-peptoids of various size were prepared and their conformational features were investigated by means of computational, spectroscopic, and X-ray crystallographic studies.


Assuntos
Peptídeos Cíclicos/química , Cristalografia por Raios X , Modelos Moleculares , Ressonância Magnética Nuclear Biomolecular , Peptídeos Cíclicos/síntese química , Conformação Proteica
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