Detalhe da pesquisa
1.
Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase.
Bioorg Med Chem
; 28(17): 115645, 2020 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32773091
2.
Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase.
Bioorg Med Chem
; 28(15): 115580, 2020 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32631562
3.
Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors.
Molecules
; 25(20)2020 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-33081246
4.
The in-vitro effect of famotidine on sars-cov-2 proteases and virus replication.
Sci Rep
; 11(1): 5433, 2021 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33686143
5.
Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
ACS Chem Biol
; 15(2): 407-415, 2020 02 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31869198
6.
Synthesis and Biological Evaluation of Lipophilic Nucleoside Analogues as Inhibitors of Aminoacyl-tRNA Synthetases.
Antibiotics (Basel)
; 8(4)2019 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31600972
7.
Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases.
Eur J Med Chem
; 173: 154-166, 2019 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30995568
8.
Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily.
Eur J Med Chem
; 174: 252-264, 2019 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31048140
9.
Family-wide analysis of aminoacyl-sulfamoyl-3-deazaadenosine analogues as inhibitors of aminoacyl-tRNA synthetases.
Eur J Med Chem
; 148: 384-396, 2018 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-29477072