Detalhe da pesquisa
1.
Deficiency of the metabolic enzyme SCHAD in pancreatic ß-cells promotes amino acid-sensitive hypoglycemia.
J Biol Chem
; 299(8): 104986, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37392854
2.
Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway.
Diabetologia
; 63(3): 577-587, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31897526
3.
Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics.
J Proteome Res
; 14(8): 3111-3122, 2015 Aug 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26151086
4.
Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.
Am J Physiol Endocrinol Metab
; 307(10): E906-18, 2014 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25249504
5.
SUCNR1 regulates insulin secretion and glucose elevates the succinate response in people with prediabetes.
J Clin Invest
; 2024 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38713514
6.
NREP contributes to development of NAFLD by regulating one-carbon metabolism in primary human hepatocytes.
Cell Chem Biol
; 30(9): 1144-1155.e4, 2023 09 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37354909
7.
m 6 A mRNA Methylation Regulates Early Pancreatic ß-Cell Differentiation.
bioRxiv
; 2023 Aug 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37577492
8.
Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses.
Elife
; 122023 Sep 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37732504
9.
m 6 A mRNA Methylation in Brown Adipose Tissue Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling Axis.
bioRxiv
; 2023 May 26.
Artigo
Inglês
| MEDLINE | ID: mdl-37292780
10.
Excess pancreatic elastase alters acinar-ß cell communication by impairing the mechano-signaling and the PAR2 pathways.
Cell Metab
; 35(7): 1242-1260.e9, 2023 07 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37339634
11.
Redox Regulation of m 6 A Methyltransferase METTL3 in Human ß-cells Controls the Innate Immune Response in Type 1 Diabetes.
bioRxiv
; 2023 Feb 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36824909
12.
E2F1 transcription factor mediates a link between fat and islets to promote ß cell proliferation in response to acute insulin resistance.
Cell Rep
; 41(1): 111436, 2022 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36198264
13.
Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.
Nat Commun
; 13(1): 7323, 2022 11 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36443308
14.
Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b.
Sci Transl Med
; 14(637): eabh3831, 2022 03 23.
Artigo
Inglês
| MEDLINE | ID: mdl-35320000
15.
Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice.
J Clin Invest
; 130(5): 2391-2407, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32250344
16.
"Omics" and "epi-omics" underlying the ß-cell adaptation to insulin resistance.
Mol Metab
; 27S: S42-S48, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31500830
17.
Human duct cells contribute to ß cell compensation in insulin resistance.
JCI Insight
; 4(8)2019 04 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30996131
18.
RADAR: differential analysis of MeRIP-seq data with a random effect model.
Genome Biol
; 20(1): 294, 2019 12 23.
Artigo
Inglês
| MEDLINE | ID: mdl-31870409
19.
Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes.
Diabetes
; 68(5): 1084-1093, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30833467
20.
m6A mRNA Methylation Regulates Human ß-Cell Biology in Physiological States and in Type 2 Diabetes.
Nat Metab
; 1(8): 765-774, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31867565