Detalhe da pesquisa
1.
Design of protein-binding proteins from the target structure alone.
Nature
; 605(7910): 551-560, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35332283
2.
Bacterial structural genomics target enabled by a recently discovered potent fungal acetyl-CoA synthetase inhibitor.
Acta Crystallogr F Struct Biol Commun
; 79(Pt 6): 137-143, 2023 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37223974
3.
Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus.
mBio
; 13(3): e0104922, 2022 06 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35604094
4.
Structural Characterization of the Reaction and Substrate Specificity Mechanisms of Pathogenic Fungal Acetyl-CoA Synthetases.
ACS Chem Biol
; 16(8): 1587-1599, 2021 08 20.
Artigo
Inglês
| MEDLINE | ID: mdl-34369755